IL41855A - Methods and apparatuses for correcting coincidence count inaccuracies in a particle analyzer - Google Patents
Methods and apparatuses for correcting coincidence count inaccuracies in a particle analyzerInfo
- Publication number
- IL41855A IL41855A IL41855A IL4185573A IL41855A IL 41855 A IL41855 A IL 41855A IL 41855 A IL41855 A IL 41855A IL 4185573 A IL4185573 A IL 4185573A IL 41855 A IL41855 A IL 41855A
- Authority
- IL
- Israel
- Prior art keywords
- pulse
- train
- sensing zone
- particle
- count
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims description 189
- 238000000034 method Methods 0.000 title claims description 52
- 239000012895 dilution Substances 0.000 claims description 31
- 238000010790 dilution Methods 0.000 claims description 31
- 238000012937 correction Methods 0.000 claims description 22
- 238000012360 testing method Methods 0.000 claims description 14
- 230000003287 optical effect Effects 0.000 claims description 13
- 238000009826 distribution Methods 0.000 claims description 11
- 230000003111 delayed effect Effects 0.000 claims description 7
- 230000008859 change Effects 0.000 claims description 6
- 239000012898 sample dilution Substances 0.000 claims description 3
- 230000002463 transducing effect Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 description 58
- 239000000725 suspension Substances 0.000 description 10
- 238000004458 analytical method Methods 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 238000006467 substitution reaction Methods 0.000 description 6
- 238000012545 processing Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000005286 illumination Methods 0.000 description 4
- 238000004364 calculation method Methods 0.000 description 3
- 238000003113 dilution method Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000009795 derivation Methods 0.000 description 2
- 239000012470 diluted sample Substances 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002226 simultaneous effect Effects 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- FEPMHVLSLDOMQC-UHFFFAOYSA-N virginiamycin-S1 Natural products CC1OC(=O)C(C=2C=CC=CC=2)NC(=O)C2CC(=O)CCN2C(=O)C(CC=2C=CC=CC=2)N(C)C(=O)C2CCCN2C(=O)C(CC)NC(=O)C1NC(=O)C1=NC=CC=C1O FEPMHVLSLDOMQC-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N15/131—Details
- G01N15/132—Circuits
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
- G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1493—Particle size
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23807972A | 1972-03-27 | 1972-03-27 | |
| US05/292,421 US3949197A (en) | 1972-09-26 | 1972-09-26 | Methods and apparatuses for correcting coincidence count errors in a particle analyzer having a sensing zone through which the particles flow |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41855A0 IL41855A0 (en) | 1973-05-31 |
| IL41855A true IL41855A (en) | 1977-05-31 |
Family
ID=26931325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41855A IL41855A (en) | 1972-03-27 | 1973-03-23 | Methods and apparatuses for correcting coincidence count inaccuracies in a particle analyzer |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5625611B2 (xx) |
| AR (1) | AR204610A1 (xx) |
| BE (1) | BE797228A (xx) |
| CH (1) | CH592303A5 (xx) |
| DE (1) | DE2314578C2 (xx) |
| FR (1) | FR2186135A5 (xx) |
| GB (1) | GB1423021A (xx) |
| IL (1) | IL41855A (xx) |
| IT (1) | IT1032020B (xx) |
| NL (1) | NL7304071A (xx) |
| SE (1) | SE391583B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2630780A1 (de) * | 1975-07-09 | 1977-01-27 | Coulter Electronics | Korrektureinrichtung fuer koinzidenzfehler in teilchenuntersuchungsgeraeten |
| JPS5338101A (en) * | 1976-09-20 | 1978-04-07 | Shimizu Construction Co Ltd | Method of excavating inside of steel pipe pile |
| JPS5918511B2 (ja) * | 1981-04-13 | 1984-04-27 | 三井不動産建設株式会社 | 共振を利用した切削方法 |
| US6744245B2 (en) * | 2001-07-27 | 2004-06-01 | Coulter International Corp. | Particle count correction method and apparatus |
| CN114486689B (zh) * | 2022-04-15 | 2022-07-05 | 南京颐兰贝生物科技有限责任公司 | 一种血细胞脉冲计数误差校正方法及校正装置 |
-
1973
- 1973-01-01 AR AR247202A patent/AR204610A1/es active
- 1973-03-23 NL NL7304071A patent/NL7304071A/xx not_active Application Discontinuation
- 1973-03-23 CH CH423873A patent/CH592303A5/xx not_active IP Right Cessation
- 1973-03-23 SE SE7304123A patent/SE391583B/xx unknown
- 1973-03-23 GB GB1424273A patent/GB1423021A/en not_active Expired
- 1973-03-23 BE BE797228A patent/BE797228A/xx unknown
- 1973-03-23 JP JP3341173A patent/JPS5625611B2/ja not_active Expired
- 1973-03-23 IL IL41855A patent/IL41855A/en unknown
- 1973-03-23 FR FR7310505A patent/FR2186135A5/fr not_active Expired
- 1973-03-23 IT IT43995/73A patent/IT1032020B/it active
- 1973-03-23 DE DE2314578A patent/DE2314578C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH592303A5 (xx) | 1977-10-31 |
| DE2314578A1 (de) | 1973-10-11 |
| AU5373673A (en) | 1974-09-26 |
| JPS499282A (xx) | 1974-01-26 |
| GB1423021A (en) | 1976-01-28 |
| JPS5625611B2 (xx) | 1981-06-13 |
| AR204610A1 (es) | 1976-02-20 |
| DE2314578C2 (de) | 1983-07-14 |
| BE797228A (fr) | 1973-07-16 |
| SE391583B (sv) | 1977-02-21 |
| IT1032020B (it) | 1979-05-30 |
| FR2186135A5 (xx) | 1974-01-04 |
| NL7304071A (xx) | 1973-10-01 |
| IL41855A0 (en) | 1973-05-31 |
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