IL41598A - Antibiotic at-125(l-(alphas,5s)-alpha-amino 3-chloro-2-isoxazoline-5-acetic acid)and a process for its preparation - Google Patents

Antibiotic at-125(l-(alphas,5s)-alpha-amino 3-chloro-2-isoxazoline-5-acetic acid)and a process for its preparation

Info

Publication number
IL41598A
IL41598A IL41598A IL4159873A IL41598A IL 41598 A IL41598 A IL 41598A IL 41598 A IL41598 A IL 41598A IL 4159873 A IL4159873 A IL 4159873A IL 41598 A IL41598 A IL 41598A
Authority
IL
Israel
Prior art keywords
antibiotic
medium
process according
compound
resin
Prior art date
Application number
IL41598A
Other languages
English (en)
Other versions
IL41598A0 (en
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL41598A0 publication Critical patent/IL41598A0/xx
Publication of IL41598A publication Critical patent/IL41598A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00—Antibiotics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL41598A 1972-03-13 1973-02-21 Antibiotic at-125(l-(alphas,5s)-alpha-amino 3-chloro-2-isoxazoline-5-acetic acid)and a process for its preparation IL41598A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23434772A 1972-03-13 1972-03-13
US00329001A US3856807A (en) 1972-03-13 1973-02-02 L-({60 s,5s)-{60 -amino-3-chloro-2-isoxazoline-5-acetic acid

Publications (2)

Publication Number Publication Date
IL41598A0 IL41598A0 (en) 1973-04-30
IL41598A true IL41598A (en) 1975-11-25

Family

ID=26927835

Family Applications (1)

Application Number Title Priority Date Filing Date
IL41598A IL41598A (en) 1972-03-13 1973-02-21 Antibiotic at-125(l-(alphas,5s)-alpha-amino 3-chloro-2-isoxazoline-5-acetic acid)and a process for its preparation

Country Status (13)

Country Link
US (1) US3856807A (xx)
JP (1) JPS5629997B2 (xx)
AR (1) AR198077A1 (xx)
AU (1) AU467524B2 (xx)
CA (1) CA984321A (xx)
CH (1) CH581698A5 (xx)
DK (1) DK132095C (xx)
FR (1) FR2183680B1 (xx)
GB (1) GB1382772A (xx)
IL (1) IL41598A (xx)
NL (1) NL7303331A (xx)
PH (1) PH9723A (xx)
SE (1) SE388434B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944562A (en) * 1974-04-17 1976-03-16 The Upjohn Company αS, 4S, 5R α-Amino-3-chloro-4-hydroxy-2-isoxazoline-5-acetic acid
US4232164A (en) * 1978-05-15 1980-11-04 The Upjohn Company Purification of AT-125
US4275214A (en) * 1978-05-15 1981-06-23 The Upjohn Company Substituted alkoxy carbonyl-3-oxo-α-phthalimido-5-isoxozolidineacetic acids
AU526380B2 (en) * 1978-05-15 1983-01-06 Upjohn Company, The 2-isoxazoline-5-acetic acid derivatives
US4225720A (en) * 1978-05-15 1980-09-30 The Upjohn Company Purification of AT-125
US4298744A (en) * 1978-05-15 1981-11-03 The Upjohn Company Method for preparing (αS,5S)-α-amino-3-chloro-2-isoxazoline-5-acetic acid (AT-125) and analogs thereof
USRE31578E (en) * 1978-05-15 1984-05-01 The Upjohn Company α(Substituted) amino-3-substituted-2-isoxazoline-5-acetic acids (esters)
US4256898A (en) * 1978-05-15 1981-03-17 The Upjohn Company α(substituted) Amino-3-substituted-2-isoxazoline-5-acetic acids (esters)
US4692538A (en) * 1982-04-14 1987-09-08 Bristol-Myers Company Trichloroethanimidic acid esters
WO2014186435A2 (en) 2013-05-14 2014-11-20 University Of Georgia Research Foundation, Inc. Compositions and methods for reducing neointima formation
JP2023504286A (ja) 2019-12-04 2023-02-02 アシュバッタ セラピューティクス， インコーポレイテッド 薬物送達のためのデンドリマー組成物および方法
JP2023504287A (ja) 2019-12-04 2023-02-02 アシュバッタ セラピューティクス， インコーポレイテッド 三分岐ｎ－アセチルガラクトサミン修飾ヒドロキシルポリアミドアミンデンドリマーおよびその使用方法

Also Published As

Publication number Publication date
GB1382772A (en) 1975-02-05
SE388434B (sv) 1976-10-04
AR198077A1 (es) 1974-05-31
CH581698A5 (xx) 1976-11-15
FR2183680B1 (xx) 1976-10-22
DK132095C (da) 1976-03-15
JPS5629997B2 (xx) 1981-07-11
IL41598A0 (en) 1973-04-30
PH9723A (en) 1976-02-27
US3856807A (en) 1974-12-24
CA984321A (en) 1976-02-24
NL7303331A (xx) 1973-09-17
AU5247773A (en) 1974-08-22
FR2183680A1 (xx) 1973-12-21
DK132095B (da) 1975-10-20
JPS4899391A (xx) 1973-12-15
AU467524B2 (en) 1975-12-04

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