IL41562A - History of morphine, their manufacture and the pharmaceutical preparations containing them - Google Patents

History of morphine, their manufacture and the pharmaceutical preparations containing them

Info

Publication number
IL41562A
IL41562A IL41562A IL4156273A IL41562A IL 41562 A IL41562 A IL 41562A IL 41562 A IL41562 A IL 41562A IL 4156273 A IL4156273 A IL 4156273A IL 41562 A IL41562 A IL 41562A
Authority
IL
Israel
Prior art keywords
hydroxy
acid addition
addition salts
cyclopropylmethylmorphinan
methoxy
Prior art date
Application number
IL41562A
Other languages
English (en)
Hebrew (he)
Other versions
IL41562A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL41562A0 publication Critical patent/IL41562A0/xx
Publication of IL41562A publication Critical patent/IL41562A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL41562A 1972-03-10 1973-02-16 History of morphine, their manufacture and the pharmaceutical preparations containing them IL41562A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23371572A 1972-03-10 1972-03-10
US00299478A US3810899A (en) 1972-03-10 1972-10-20 2-hydroxy-n-substituted-morphinan derivatives

Publications (2)

Publication Number Publication Date
IL41562A0 IL41562A0 (en) 1973-04-30
IL41562A true IL41562A (en) 1977-04-29

Family

ID=26927165

Family Applications (1)

Application Number Title Priority Date Filing Date
IL41562A IL41562A (en) 1972-03-10 1973-02-16 History of morphine, their manufacture and the pharmaceutical preparations containing them

Country Status (11)

Country Link
US (1) US3810899A (et)
AU (1) AU475007B2 (et)
CA (1) CA1014954A (et)
CH (2) CH586205A5 (et)
DK (1) DK138988B (et)
FR (1) FR2181800B1 (et)
GB (1) GB1402502A (et)
IL (1) IL41562A (et)
NL (1) NL7303050A (et)
PH (1) PH11649A (et)
SE (1) SE403908B (et)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
US4410700A (en) * 1980-07-03 1983-10-18 The United States Of America As Represented By The Department Of Health And Human Services Preparation of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines by optical resolution
US4496762A (en) * 1983-03-29 1985-01-29 Eastman Kodak Company Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide
US5905153A (en) * 1996-10-02 1999-05-18 Roche Vitamins Inc. Process for preparing (9α,13α,14α)-1-(3-methoxy-morphinan-17-yl)alkanones
US5849917A (en) * 1996-10-02 1998-12-15 Roche Vitamins Inc. Process for the preparation of isoquinoline compounds
ATE438649T1 (de) * 2006-04-21 2009-08-15 Zach System Spa Verfahren zur herstellung von dorzolamid

Also Published As

Publication number Publication date
AU475007B2 (en) 1976-08-12
DK138988B (da) 1978-11-27
FR2181800A1 (et) 1973-12-07
AU5222773A (en) 1974-08-15
DK138988C (et) 1979-05-07
PH11649A (en) 1978-05-08
CA1014954A (en) 1977-08-02
FR2181800B1 (et) 1976-05-14
CH586205A5 (et) 1977-03-31
IL41562A0 (en) 1973-04-30
GB1402502A (en) 1975-08-13
US3810899A (en) 1974-05-14
CH591449A5 (et) 1977-09-15
SE403908B (sv) 1978-09-11
NL7303050A (et) 1973-09-12

Similar Documents

Publication Publication Date Title
DK156719B (da) Analogifremgangsmaade til fremstilling af 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphanforbindelser eller syreadditionssalte deraf
DK141624B (da) Analogifremgangsmåde til fremstilling af morphinanderivater.
US3639407A (en) Novel 1 2 3 4 5 6-hexahydro-6-phenyl-2 6-methano-3-benzazocines
HU176479B (en) Process for preparing new n-/methoxymethyl-furyl-methyl/-6,7-benzomorphans and -morphians further acid addition snlts thereof
US3336316A (en) Benzocyclopentaindolizines and dibenzindolizines
IL41562A (en) History of morphine, their manufacture and the pharmaceutical preparations containing them
US3914233A (en) 4-Hydroxy-N-substituted morphinan derivatives
US3378561A (en) 1-beta-arylthioethyltetrahydro-isoquinolines
US3914232A (en) 2-And 4-acryloxy-N-substituted-morphinan derivatives
US2959594A (en) Iso-benzmorphan derivatives
GB2054581A (en) alpha -Phenyl-2-pyrrolidinemethanol derivatives
US3452086A (en) Substituted tartranilic acid resolving agents
US4194044A (en) Process for preparing 3-phenoxy morphinans
US4247697A (en) 3-Phenoxy morphinans and their derivatives
US4139534A (en) Process for the preparation of 14-hydroxymorphinan derivatives
US4058531A (en) Process for the preparation of 14-hydroxymorphinan derivatives
US4243808A (en) 4-Pyridinamine derivatives
Lewis et al. Novel analgesics and molecular rearrangements in the morphine-thebaine group. 28. Derivatives of 6, 14-endo-etheno-7-Oxo-6, 7, 8, 14-tetrahydrothebaine and 6, 14-endo-etheno-6, 7, 8, 14-tetrahydrothebaine
US3914234A (en) 2-Lower alkoxy-N-substituted-morphinan derivatives
US4163853A (en) 1-(P-phenoxy)benzyl-1,2,3,4,5,6,7,8-octahydroisoquinolines
US4013667A (en) 2,2-Diaryl-3-(1-azabicyclo[2.2.2]oct-2-yl)propionamides and intermediates thereto
US3553223A (en) Acid catalyzed cyclization of tetrahydropyridines containing an electron withdrawing group on the nitrogen
US3796715A (en) 8-alkoxy-3,4-dihydroisoquinolines
DE2311881A1 (de) Morphinanderivate
US3576812A (en) 1,5-methano-3-benzazocine derivatives