IL41083A - 6-(phenoxyacetoxy-c3-6-alkanoyl)amino-penicillanic acid derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents
6-(phenoxyacetoxy-c3-6-alkanoyl)amino-penicillanic acid derivatives,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL41083A IL41083A IL41083A IL4108372A IL41083A IL 41083 A IL41083 A IL 41083A IL 41083 A IL41083 A IL 41083A IL 4108372 A IL4108372 A IL 4108372A IL 41083 A IL41083 A IL 41083A
- Authority
- IL
- Israel
- Prior art keywords
- salts
- acid
- formula
- group
- stands
- Prior art date
Links
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical class [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 title claims abstract 4
- 238000004519 manufacturing process Methods 0.000 title claims 5
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims abstract 26
- 239000002253 acid Substances 0.000 claims abstract 12
- 125000000217 alkyl group Chemical group 0.000 claims abstract 11
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 4
- 125000005843 halogen group Chemical group 0.000 claims abstract 4
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims 22
- 150000001875 compounds Chemical class 0.000 claims 11
- 239000000126 substance Substances 0.000 claims 11
- 150000004677 hydrates Chemical class 0.000 claims 9
- -1 methoxy, nitro, dimethylamino Chemical group 0.000 claims 7
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 4
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims 4
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 claims 4
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 239000011734 sodium Substances 0.000 claims 4
- 229910052708 sodium Inorganic materials 0.000 claims 4
- 229910052801 chlorine Inorganic materials 0.000 claims 3
- 125000001309 chloro group Chemical group Cl* 0.000 claims 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 3
- 125000002252 acyl group Chemical group 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 2
- ACAZKHULUUVWCY-UHFFFAOYSA-N 6beta-hexanoylamino-penicillanic acid Natural products S1C(C)(C)C(C(O)=O)N2C(=O)C(NC(=O)CCCCC)C21 ACAZKHULUUVWCY-UHFFFAOYSA-N 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 claims 1
- UHNHTTIUNATJKL-UHFFFAOYSA-N n-methylmethanesulfonamide Chemical group CNS(C)(=O)=O UHNHTTIUNATJKL-UHFFFAOYSA-N 0.000 claims 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical class OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 claims 1
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25C—HAND-HELD NAILING OR STAPLING TOOLS; MANUALLY OPERATED PORTABLE STAPLING TOOLS
- B25C5/00—Manually operated portable stapling tools; Hand-held power-operated stapling tools; Staple feeding devices therefor
- B25C5/02—Manually operated portable stapling tools; Hand-held power-operated stapling tools; Staple feeding devices therefor with provision for bending the ends of the staples on to the work
- B25C5/0221—Stapling tools of the table model type, i.e. tools supported by a table or the work during operation
- B25C5/0257—Stapling tools of the table model type, i.e. tools supported by a table or the work during operation without an anvil, e.g. using staples of particular shape bent during the stapling operation without the use of external clinching means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25C—HAND-HELD NAILING OR STAPLING TOOLS; MANUALLY OPERATED PORTABLE STAPLING TOOLS
- B25C5/00—Manually operated portable stapling tools; Hand-held power-operated stapling tools; Staple feeding devices therefor
- B25C5/06—Manually operated portable stapling tools; Hand-held power-operated stapling tools; Staple feeding devices therefor without provision for bending the ends of the staples on to the work
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/58—Preparation of carboxylic acid halides
- C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH43472A CH565183A5 (enrdf_load_stackoverflow) | 1971-09-09 | 1972-01-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41083A0 IL41083A0 (en) | 1973-02-28 |
| IL41083A true IL41083A (en) | 1976-02-29 |
Family
ID=4186930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41083A IL41083A (en) | 1972-01-12 | 1972-12-14 | 6-(phenoxyacetoxy-c3-6-alkanoyl)amino-penicillanic acid derivatives,their manufacture and pharmaceutical compositions containing them |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4880587A (enrdf_load_stackoverflow) |
| BE (1) | BE793885A (enrdf_load_stackoverflow) |
| IL (1) | IL41083A (enrdf_load_stackoverflow) |
| ZA (1) | ZA728771B (enrdf_load_stackoverflow) |
-
0
- BE BE793885D patent/BE793885A/xx unknown
-
1972
- 1972-12-12 ZA ZA728771A patent/ZA728771B/xx unknown
- 1972-12-14 IL IL41083A patent/IL41083A/en unknown
-
1973
- 1973-01-10 JP JP48005356A patent/JPS4880587A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA728771B (en) | 1973-08-29 |
| IL41083A0 (en) | 1973-02-28 |
| BE793885A (en) | 1973-07-11 |
| JPS4880587A (enrdf_load_stackoverflow) | 1973-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8102140A1 (es) | Un procedimiento para la preparacion de compuestos de cefem y cefam | |
| HUT40101A (en) | Process for producing quinolin-carboxylic acid derivatives and pharmaceutical compositions containing them as active agents | |
| US3821198A (en) | Derivatives of 6-amino penicillanic acid | |
| IL41083A (en) | 6-(phenoxyacetoxy-c3-6-alkanoyl)amino-penicillanic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
| GB1256750A (enrdf_load_stackoverflow) | ||
| GB1246051A (en) | Improvements in or relating to isoquinoline derivatives | |
| GB1384035A (en) | Amino alkyl esters of 2-anilino nicotinic acid and their preparation | |
| GB1385831A (en) | Acylamino-cephem-carboxylic acids and process for their preparation | |
| ATE3769T1 (de) | 1-imidazol-2-yliden-3-thienyl-harnstoffderivate verfahren zu deren herstellung und pharmazeutische zusammensetzungen. | |
| US3880842A (en) | Cephalosporin derivatives | |
| US3812110A (en) | 7-(1,4-cyclohexadienyl-acylamino)cephalosporins | |
| GB1374406A (en) | 1-substituted-2- 4,-cinnamyl piperazin-1,-yl methyl- benzimidazoles their process of preparation and their therapeutic application | |
| GB1113802A (en) | Improvements in or relating to substituted quinolines and the manufacture thereof | |
| US3886140A (en) | Penicillin derivatives | |
| GB1377610A (en) | 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof | |
| GB1082943A (en) | Derivatives of 7-aminocephalosporanic acid | |
| GB1420728A (en) | Cephalosporins | |
| GB1369888A (en) | Substituted amidines | |
| GB1401490A (en) | Bronchodilatory and/or bronchial spasm reducing compositions | |
| GB742672A (en) | Improvements in and relating to analgesic preparations | |
| GB1271709A (en) | Dithiocarbamic acid esters and process for their manufacture | |
| GB1308832A (en) | Pyridazine derivatives | |
| IE36699L (en) | Boron compounds | |
| GB796359A (en) | A new salt of phenoxymethyl penicillin and methods for its production | |
| GB1089012A (en) | Improvements in or relating to the production of derivatives of nitrofuran |