IL40785A - Pharmaceutical compositions comprising 2-p-chlorophenoxy-2-methyl-propionic acid and tocopherol - Google Patents
Pharmaceutical compositions comprising 2-p-chlorophenoxy-2-methyl-propionic acid and tocopherolInfo
- Publication number
- IL40785A IL40785A IL40785A IL4078572A IL40785A IL 40785 A IL40785 A IL 40785A IL 40785 A IL40785 A IL 40785A IL 4078572 A IL4078572 A IL 4078572A IL 40785 A IL40785 A IL 40785A
- Authority
- IL
- Israel
- Prior art keywords
- composition
- tocopherol
- chlorophenoxy
- ester
- pharmaceutically acceptable
- Prior art date
Links
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title claims abstract 6
- 229960001295 tocopherol Drugs 0.000 title claims abstract 6
- 239000011732 tocopherol Substances 0.000 title claims abstract 6
- 229930003799 tocopherol Natural products 0.000 title claims abstract 4
- 235000010384 tocopherol Nutrition 0.000 title claims abstract 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title claims abstract 4
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical compound OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 title claims abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 3
- 239000000203 mixture Substances 0.000 claims abstract 12
- 150000002148 esters Chemical class 0.000 claims abstract 6
- 230000000694 effects Effects 0.000 claims abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical compound CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 claims 1
- 159000000007 calcium salts Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 239000007903 gelatin capsule Substances 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000001384 succinic acid Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229940111131 antiinflammatory and antirheumatic product propionic acid derivative Drugs 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- -1 nicotinoyloxy groups Chemical group 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 150000005599 propionic acid derivatives Chemical class 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- 229940045997 vitamin a Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5839871A GB1382587A (en) | 1971-12-16 | 1971-12-16 | Pharmaceutical compositions comprising 2-rho-chlorophenoxy-2- methylpropionic acid or a derivative and a tocopherol possessing vitamin e activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40785A0 IL40785A0 (en) | 1973-02-28 |
| IL40785A true IL40785A (en) | 1976-02-29 |
Family
ID=10481514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40785A IL40785A (en) | 1971-12-16 | 1972-11-09 | Pharmaceutical compositions comprising 2-p-chlorophenoxy-2-methyl-propionic acid and tocopherol |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4867420A (enExample) |
| AU (1) | AU470387B2 (enExample) |
| BE (1) | BE792855A (enExample) |
| CA (1) | CA981579A (enExample) |
| DE (1) | DE2261504A1 (enExample) |
| FR (1) | FR2163736B1 (enExample) |
| GB (1) | GB1382587A (enExample) |
| IE (1) | IE36820B1 (enExample) |
| IL (1) | IL40785A (enExample) |
| NL (1) | NL7216837A (enExample) |
| ZA (1) | ZA727855B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2730231B1 (fr) * | 1995-02-02 | 1997-04-04 | Fournier Sca Lab | Association de fenofibrate et de vitamine e, utilisation en therapeutique |
-
0
- BE BE792855D patent/BE792855A/xx unknown
-
1971
- 1971-12-16 GB GB5839871A patent/GB1382587A/en not_active Expired
-
1972
- 1972-11-02 IE IE1489/72A patent/IE36820B1/xx unknown
- 1972-11-06 ZA ZA727855A patent/ZA727855B/xx unknown
- 1972-11-09 IL IL40785A patent/IL40785A/en unknown
- 1972-11-10 AU AU48736/72A patent/AU470387B2/en not_active Expired
- 1972-11-16 CA CA156,665A patent/CA981579A/en not_active Expired
- 1972-12-12 NL NL7216837A patent/NL7216837A/xx not_active Application Discontinuation
- 1972-12-15 FR FR7244922A patent/FR2163736B1/fr not_active Expired
- 1972-12-15 DE DE19722261504 patent/DE2261504A1/de active Pending
- 1972-12-15 JP JP47126036A patent/JPS4867420A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL40785A0 (en) | 1973-02-28 |
| FR2163736B1 (enExample) | 1976-03-05 |
| DE2261504A1 (de) | 1973-06-28 |
| JPS4867420A (enExample) | 1973-09-14 |
| AU4873672A (en) | 1974-05-16 |
| GB1382587A (en) | 1975-02-05 |
| FR2163736A1 (enExample) | 1973-07-27 |
| IE36820B1 (en) | 1977-03-02 |
| CA981579A (en) | 1976-01-13 |
| IE36820L (en) | 1973-06-16 |
| ZA727855B (en) | 1973-08-29 |
| AU470387B2 (en) | 1976-03-11 |
| BE792855A (fr) | 1973-06-15 |
| NL7216837A (enExample) | 1973-06-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1389814A (en) | Cysteine derivatives and production thereof | |
| EP0295637B1 (en) | Lipid regulating compositions | |
| IL37026A (en) | Pharmaceutical preparations containing vitamin a derivatives | |
| US4233316A (en) | Analgesic potentiation | |
| HUT49614A (en) | Process for producing cefalosporin derivatives and pharmaceutical compositions comprising these compounds | |
| US4233317A (en) | Analgesic potentiation | |
| ES427079A1 (es) | Un metodo de preparacion de fenotiazidas sustituidas por fluor en la posicion 7. | |
| PT85871B (en) | Process for the preparation of orally administrable pharmaceutical compositions which contain chenodeoxycholic acid or deoxycholic acid or a salt of either of these acids any of wich may be used alone or is combination with a synergist | |
| AP460A (en) | Naphthyl derivative for treatment method. | |
| US4233314A (en) | Analgesic potentiation | |
| GB1291864A (en) | Mono thiachromone-2-carboxylic acids | |
| IL40785A (en) | Pharmaceutical compositions comprising 2-p-chlorophenoxy-2-methyl-propionic acid and tocopherol | |
| EP0127297B1 (en) | Vitamin composition with enhanced bioavailability and method of administering same | |
| US3917832A (en) | Compositions comprising d-thyroxine and d-triiodothyronine | |
| US4590183A (en) | Gastric cytoprotection with sodium thiosulfate in oral administration of aspirin | |
| KR930012018A (ko) | 약제학적 조성물 | |
| GB1411701A (en) | Compositions containing compounds of the eburnane structure | |
| GB1456324A (en) | Cycloalkyl phenoxy carboxylic acid derivatives processes for producing them and compositions containing them | |
| US2910403A (en) | Anti hypertensive compositions comprising 2-methyl-5, 8-dimethoxychromone and acetamides | |
| GB955627A (en) | Therapeutic composition comprising antibiotics | |
| US4585764A (en) | Gastric cytoprotection with 3,3'-thiobis[propanoic acid] in oral administration of aspirin | |
| KR840006810A (ko) | 세팔로스포린 에스테르의 제조방법 | |
| IE34275L (en) | Alpha-hydrazino acids | |
| GB1280244A (en) | Serum triglyceride-lowering compositions | |
| JPS6123796B2 (enExample) |