IL39078A - Pharmaceutical compositions containing 16-lower alkyl or 16,16-diloweralkyl prostaglandins of the a and e types - Google Patents
Pharmaceutical compositions containing 16-lower alkyl or 16,16-diloweralkyl prostaglandins of the a and e typesInfo
- Publication number
- IL39078A IL39078A IL39078A IL3907872A IL39078A IL 39078 A IL39078 A IL 39078A IL 39078 A IL39078 A IL 39078A IL 3907872 A IL3907872 A IL 3907872A IL 39078 A IL39078 A IL 39078A
- Authority
- IL
- Israel
- Prior art keywords
- pge2
- pgei
- preparation
- methyl
- pga2
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 title claims 3
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 229960002986 dinoprostone Drugs 0.000 claims abstract 8
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 238000007910 systemic administration Methods 0.000 claims abstract 2
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 claims 7
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 claims 6
- -1 PGAX Chemical compound 0.000 claims 5
- 101100310593 Candida albicans (strain SC5314 / ATCC MYA-2876) SOD4 gene Proteins 0.000 claims 4
- MYHXHCUNDDAEOZ-UHFFFAOYSA-N Prostaglandin A&2% Natural products CCCCCC(O)C=CC1C=CC(=O)C1CC=CCCCC(O)=O MYHXHCUNDDAEOZ-UHFFFAOYSA-N 0.000 claims 4
- 101100190148 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) PGA2 gene Proteins 0.000 claims 4
- MYHXHCUNDDAEOZ-FOSBLDSVSA-N prostaglandin A2 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1C=CC(=O)[C@@H]1C\C=C/CCCC(O)=O MYHXHCUNDDAEOZ-FOSBLDSVSA-N 0.000 claims 4
- 150000002148 esters Chemical class 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 230000001262 anti-secretory effect Effects 0.000 claims 1
- 230000000767 anti-ulcer Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 150000004702 methyl esters Chemical class 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- QAOBBBBDJSWHMU-WMBBNPMCSA-N 16,16-dimethylprostaglandin E2 Chemical compound CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O QAOBBBBDJSWHMU-WMBBNPMCSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19189971A | 1971-10-22 | 1971-10-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL39078A0 IL39078A0 (en) | 1972-05-30 |
| IL39078A true IL39078A (en) | 1976-08-31 |
Family
ID=22707366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL39078A IL39078A (en) | 1971-10-22 | 1972-03-26 | Pharmaceutical compositions containing 16-lower alkyl or 16,16-diloweralkyl prostaglandins of the a and e types |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE781978A (fr) |
| DE (1) | DE2216717C2 (fr) |
| IL (1) | IL39078A (fr) |
| NL (1) | NL7204870A (fr) |
| PH (1) | PH9797A (fr) |
| ZA (1) | ZA721937B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966962A (en) * | 1975-03-27 | 1976-06-29 | The Upjohn Company | Triacetin solutions of PGE-type compounds |
| US4310543A (en) * | 1980-10-09 | 1982-01-12 | Hoffmann-La Roche Inc. | Prostaglandin compositions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1584563A (fr) * | 1967-06-26 | 1969-12-26 |
-
1972
- 1972-03-21 ZA ZA721937A patent/ZA721937B/xx unknown
- 1972-03-26 IL IL39078A patent/IL39078A/en unknown
- 1972-04-03 PH PH13410A patent/PH9797A/en unknown
- 1972-04-07 DE DE2216717A patent/DE2216717C2/de not_active Expired
- 1972-04-12 BE BE781978A patent/BE781978A/fr not_active IP Right Cessation
- 1972-04-12 NL NL7204870A patent/NL7204870A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2216717C2 (de) | 1984-05-17 |
| ZA721937B (en) | 1972-12-27 |
| PH9797A (en) | 1976-03-17 |
| IL39078A0 (en) | 1972-05-30 |
| NL7204870A (fr) | 1973-04-25 |
| BE781978A (fr) | 1972-10-12 |
| DE2216717A1 (de) | 1973-04-26 |
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