IL38378A0 - Steroids of the androstane series and their preparation - Google Patents

Steroids of the androstane series and their preparation

Info

Publication number
IL38378A0
IL38378A0 IL7138378A IL3837871A IL38378A0 IL 38378 A0 IL38378 A0 IL 38378A0 IL 7138378 A IL7138378 A IL 7138378A IL 3837871 A IL3837871 A IL 3837871A IL 38378 A0 IL38378 A0 IL 38378A0
Authority
IL
Israel
Prior art keywords
steroids
preparation
androstane series
androstane
series
Prior art date
Application number
IL7138378A
Other versions
IL38378A (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IL38378A0 publication Critical patent/IL38378A0/en
Publication of IL38378A publication Critical patent/IL38378A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
IL7138378A 1970-12-17 1971-12-16 3 -hydroxy-androstane-17 -carboxylic acid 17 -carboxaldehyde and 17 -carboxamide derivatives and their preparation IL38378A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB6007070 1970-12-17
GB6006470A GB1380246A (en) 1970-12-17 1970-12-17 3alpha-hydroxy-androstanes and esters thereof

Publications (2)

Publication Number Publication Date
IL38378A0 true IL38378A0 (en) 1972-02-29
IL38378A IL38378A (en) 1979-01-31

Family

ID=26267810

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7138378A IL38378A (en) 1970-12-17 1971-12-16 3 -hydroxy-androstane-17 -carboxylic acid 17 -carboxaldehyde and 17 -carboxamide derivatives and their preparation

Country Status (7)

Country Link
AU (1) AU473307B2 (en)
BE (1) BE776791A (en)
DE (1) DE2162595A1 (en)
FR (1) FR2118123B1 (en)
GB (1) GB1380246A (en)
IL (1) IL38378A (en)
NL (1) NL7117256A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434919A (en) * 1972-06-15 1976-05-12 Glaxo Lab Ltd 3alpha-hydroxy androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
ES2738526T3 (en) 2011-10-14 2020-01-23 Sage Therapeutics Inc Compounds 19-norpregnano 3,3-disubstituted, compositions and uses thereof
RS60420B1 (en) 2013-04-17 2020-07-31 Sage Therapeutics Inc 19-nor neuroactive steroids for methods of treatment
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
AU2014256229B2 (en) 2013-04-17 2018-10-04 Sage Therapeutics, Inc. 19-nor C3,3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
PL3021852T3 (en) 2013-07-19 2021-07-05 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JP6466942B2 (en) 2013-08-23 2019-02-06 セージ セラピューティクス, インコーポレイテッド Neuroactive steroids, compositions and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
HUE051488T2 (en) 2014-10-16 2021-03-01 Sage Therapeutics Inc Preparations and methods for treating central nervous system disorders
WO2016061527A1 (en) 2014-10-16 2016-04-21 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
US10774108B2 (en) 2014-11-27 2020-09-15 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
PL3250210T3 (en) 2015-01-26 2021-07-26 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
JP6875996B2 (en) 2015-02-20 2021-05-26 セージ セラピューティクス, インコーポレイテッド Neurostimulatory steroids, compositions, and their use
JP7049313B2 (en) * 2016-07-11 2022-04-06 セージ セラピューティクス, インコーポレイテッド C17, C20, and C21 substitution neurostimulatory steroids and how to use them
ES2992037T3 (en) 2016-07-11 2024-12-05 Sage Therapeutics Inc C7, C12 and C16 substituted neuroactive steroids and their methods of use
AR114044A1 (en) * 2017-12-22 2020-07-15 Sage Therapeutics Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISORDERS IN THE CENTRAL NERVOUS SYSTEM
ES2991092T3 (en) * 2017-12-22 2024-12-02 Sage Therapeutics Inc 19-homo,3-alpha-hydroxy-steroid-20-one compounds for the treatment of CNS disorders
CR20240234A (en) 2019-05-31 2024-07-09 Sage Therapeutics Inc NEUROACTIVE STEROIDS AND THEIR COMPOSITIONS (Divisional 2021-629)

Also Published As

Publication number Publication date
AU3695871A (en) 1973-06-21
BE776791A (en) 1972-06-16
GB1380246A (en) 1975-01-08
IL38378A (en) 1979-01-31
NL7117256A (en) 1972-06-20
AU473307B2 (en) 1976-06-17
DE2162595A1 (en) 1972-07-06
FR2118123B1 (en) 1975-11-28
FR2118123A1 (en) 1972-07-28

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