AU3695871A - Anaesthetic androstanes - Google Patents

Anaesthetic androstanes

Info

Publication number
AU3695871A
AU3695871A AU36958/71A AU3695871A AU3695871A AU 3695871 A AU3695871 A AU 3695871A AU 36958/71 A AU36958/71 A AU 36958/71A AU 3695871 A AU3695871 A AU 3695871A AU 3695871 A AU3695871 A AU 3695871A
Authority
AU
Australia
Prior art keywords
androstanes
anaesthetic
anaesthetic androstanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU36958/71A
Other versions
AU473307B2 (en
Inventor
Hanley Phillipps Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of AU3695871A publication Critical patent/AU3695871A/en
Application granted granted Critical
Publication of AU473307B2 publication Critical patent/AU473307B2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
AU36958/71A 1970-12-17 1971-12-16 Anaesthetic androstanes Expired AU473307B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB6006470A GB1380246A (en) 1970-12-17 1970-12-17 3alpha-hydroxy-androstanes and esters thereof
GB6007070 1970-12-17

Publications (2)

Publication Number Publication Date
AU3695871A true AU3695871A (en) 1973-06-21
AU473307B2 AU473307B2 (en) 1976-06-17

Family

ID=26267810

Family Applications (1)

Application Number Title Priority Date Filing Date
AU36958/71A Expired AU473307B2 (en) 1970-12-17 1971-12-16 Anaesthetic androstanes

Country Status (7)

Country Link
AU (1) AU473307B2 (en)
BE (1) BE776791A (en)
DE (1) DE2162595A1 (en)
FR (1) FR2118123B1 (en)
GB (1) GB1380246A (en)
IL (1) IL38378A (en)
NL (1) NL7117256A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434919A (en) * 1972-06-15 1976-05-12 Glaxo Lab Ltd 3alpha-hydroxy androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
EP3572417A3 (en) 2011-10-14 2020-03-25 Sage Therapeutics, Inc. 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
RU2700264C2 (en) 2013-04-17 2019-09-16 Сейдж Терапьютикс, Инк. 19-nor neuroactive steroids and methods of using them
KR102239541B1 (en) 2013-04-17 2021-04-14 세이지 테라퓨틱스, 인크. 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
EP3868382A1 (en) 2013-07-19 2021-08-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
LT3488852T (en) 2013-08-23 2021-02-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
BR112017007902B1 (en) 2014-10-16 2023-12-05 Sage Therapeutics, Inc COMPOUND AND ITS SALT, PHARMACEUTICAL COMPOSITION AND USE OF SAID COMPOUND AND ITS SALT IN THE MANUFACTURE OF A MEDICINE FOR THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM
LT3206493T (en) 2014-10-16 2020-08-25 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
SI3224269T1 (en) * 2014-11-27 2020-10-30 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
ES2857082T3 (en) 2015-01-26 2021-09-28 Sage Therapeutics Inc Compositions and methods for the treatment of CNS disorders
JP6875996B2 (en) 2015-02-20 2021-05-26 セージ セラピューティクス， インコーポレイテッド Neurostimulatory steroids, compositions, and their use
DK3481844T3 (en) 2016-07-11 2024-07-22 Sage Therapeutics Inc C7, C12 and C16 substituted neuroactive steroids and their methods of use
MA45599A (en) * 2016-07-11 2019-05-15 Sage Therapeutics Inc NEUROACTIVE STEROIDS SUBSTITUTED FOR C17, C20 AND C21 AND THEIR USE PROCEDURES
CN118772223A (en) * 2017-12-22 2024-10-15 萨奇治疗股份有限公司 Compositions and methods for treating central nervous system disorders
BR112020012712A8 (en) * 2017-12-22 2022-03-03 Sage Therapeutics Inc Compound or pharmaceutically acceptable salt thereof, pharmaceutical composition and uses of said compound for the treatment of CNS disorders
WO2020243488A1 (en) 2019-05-31 2020-12-03 Sage Therapeutics, Inc. Neuroactive steroids and compositions thereof

Also Published As

Publication number Publication date
FR2118123A1 (en) 1972-07-28
IL38378A (en) 1979-01-31
IL38378A0 (en) 1972-02-29
AU473307B2 (en) 1976-06-17
DE2162595A1 (en) 1972-07-06
GB1380246A (en) 1975-01-08
NL7117256A (en) 1972-06-20
FR2118123B1 (en) 1975-11-28
BE776791A (en) 1972-06-16

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