IL35336A - Syringe for injection of freshly mixed liquid-powder - Google Patents
Syringe for injection of freshly mixed liquid-powderInfo
- Publication number
- IL35336A IL35336A IL35336A IL3533670A IL35336A IL 35336 A IL35336 A IL 35336A IL 35336 A IL35336 A IL 35336A IL 3533670 A IL3533670 A IL 3533670A IL 35336 A IL35336 A IL 35336A
- Authority
- IL
- Israel
- Prior art keywords
- tubular member
- syringe assembly
- assembly according
- inner tubular
- holder
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00593—Hand tools of the syringe type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
Syringe for injection of freshly mixed Liquid-Powder
3-npD Π331ΠΡ.Π|73Κ IDTiyn *?W Π τπ^ yi-tD
S P E C I F I C A T I O .
This invention 2*elates to a device for injection of solutions or dispersions of a solid medicant in a liquid carrier and more particularly to a hypodermic syringe adapted to contain dry solids separate and apart from. the carrier liquids until, immediately prior to administration, the liquid is caused to flow into the compartment containing the solid material for injection of the solution or mixture formed thereof.
To the present, it has been the practice to make use of stock solutions housed within a container of relatively large capacity, and from which increments can be removed, for administration by a suitable syringe. This procedure is deemed to be unsatisfactory by reason of the fact that most solutions of the type described are of insufficient stability to militate against change before the stock solution or mixture has been used up. With a liquid composition of short "shelf life", utility may become dissipated before complete utilization.
The most effective means for maintaining shelf life over extended periods of time is to maintain complete separation between the liquid carrier and the solid' medicant until immediately prior to use. Maintenance of solid-liquid separation until use presents other problems with respect to ejecting and administering the solution or dispersion containing the necessary concentration of ingredients and under the most sanitary conditions. The usual practice is to introduce the solids into the liquid for solution or disper
procedure requires the use of at least three separate containers and their maintenance under sterile conditions, as well as accurate measurement of the ingredients .
It is an object of this invention to provide a single device in which accurately measured amounts of solid medicant and liquid carrier can be maintained in a completely separated relation.; in which the measured amounts of liquid carrier and solid medicant can be brought together immediately prior to injection; and in which the freshly formed mixture can be injected, all while maintaining the ingredients in a sealed and sanitary state, without exposure to the outside atmosphere and in which the entire operation for admixture or solution and administration can be carried out with one hand.
It is another object to provide a disposable syringe adapted to house the liquid and solids in separately sealed compartments and in which the mixture of liquid and solids can be effected entirely within the confines of the syringe to provide a freshly prepared solution or dispersion of the measured amounts of the ingredients and from which the freshly prepared solution or dispersion can be injected in the manner desired for use.
Other objects and advantages of this Invention will hereinafter appear and for purposes of illustration, but not of limitation, an embodiment of the invention is shown in the accompanying drawings in which:
Fig. 1 is a sectional elevational view of a syringe embodying the features of this invention with the elements illustrated in osition rior to use
syringe shown in Pig. 1 with the syringe partially actuated to effect displacement of the liquid carrier from the liqui compartment to the solid compartment for solution or admixture therewithj
Pig. 3 is a sectional elevational view of the syringe shown in Figs. 1 and 2 with the syringe in fully actuated position to effect displacement of the freshly prepared solution from the solids compartment for injection
Fig. 4 is a top plan view of the floating piston seal embodied in the liquid chamber; and
Fig. 5 is a sectional view taken alon the line '5-5 of Fig. 4.
With reference to the drawings, the syringe embodying the features of this invention comprises an outer casing 1 in the form of an elongate tubular member, formed of glass, plastics or the like, having a bore 2 extending continuously therethrough from an open rearward end 3 to a forward open-ended neck portion 4. The forward open end is adapted to be sealed by means of a sealing disc member 5 dimensioned to be greater than the opening at the forward end and to abut the outwardly extending annular lip 6 on th end of the neck portion. The rearward end of the tubular . member is formed with an outwardly extending flange 3a whic serves as a finger grip.
The hypodermic needle 7 is mounted in a needle hub 8, in the form of a cylindrical member, having an outwardly extending flange portion 9 at its rearward end and a threaded portion 10 in the peripheral surface at the forwar
member 5 in sealing relation onto the open end of the casin 1 and to mount the needle hub 8 for axial displacement in the direction toward and away from the casing 1 with the rearward end 11 of the needle 7 in endwise alignment with the sealing disc member 5 and forwardly thereof, when in normal retracted position, and to pierce the_ disc member an extend into the interior of the casing 1 when in operated position. Such means is illustrated as comprising a cup-shaped member 12 having a rearward end portion 13 which is crimped about the outx^ardly extending lip 6 with the sealin disc 5 thereon securely to position the disc in sealing re-lationship across the open end of the casing. The body portion of the cup-shaped member, having a diameter less than the flanged portion 9> extends forwardly for a distanc and then is formed with an inwardly turned portion 14 at it forward end to define an opening 15 corresponding to the cross-sectional dimension of the needle hub 8 to enable relative sliding movement therein. The needle hub 8 and the supported needle 7 are continuously urged towards operated position by means of a tension spring, in the form of a coi spring 16, which surrounds the needle hub, with one end abutting the shelf lk while the other end abuts the annular flange 9 on the rearward end of the needle hub 8.
The needle hub is held in its normal retracted position v/ith the rearward end 11 of the needle 7 within th cup immediately in advance of the sealing disc 5» as by means of a needle cover 17 having a cupped rearward end portion 18 dimensioned to correspond wit the cross-section
dimensioned to receive the end- portion of the needle 7 extending forwardly beyond the needle hub in protection thereof. The internal wall of the cup portion 18 is formed with a threaded portion 18 for threaded engagement -with the forward end portion of the needle hub whereby the needle cover is threaded onto the threaded end of the needle hub by an amount to bring the flanged portion 19 into engagement with the cap 12 whereby the needle hub is retained in retracted position with the rearward end of the needle adjacent the front. all of the sealing disc and with the tension spring 16 in tensioned relation such that, when the cover is 'removed, the needle hub is released for axial displacement. Thus the tensioned coil spring 16 becomes effective to displace the needle hub in the rearward direction automatically to project the end of the needle 7 through the sealing disc 5 and into the interior of the casing 1.
A second tubular member 20 of glass,, plastic or the like material is dimensioned to have an outer wall to wall dimension which is less than the inner wall to wall dimension of the tubular member 1 to enable the former to be telescoped through the interior of the outer tubular member 1. The second tubular member is similarly formed with a passage 21 extending from the open rearward end 22 through a neck portion 23 of smaller cross-section at the forward end. The forward neck end portion of the second tubular member is fitted with a rubber stopper 24 including an outer ribbed portion 25 fitted in gripping relationship about the neck and extending laterally beyond the walls of the second tubular member for a distance to effect sealing engagement
the second tubular member is capable of the function of a piston movable axially relative the outer tubular member 1 thereby to provide a piston and cylinder arrangement between the two tubular members.
The rubber stopper 2 has a disc portion 26 which normally spans the forward end of the passage to seal the tubular member. It is further formed -with one or more openings 27 in the lateral portions beyond the passage to enable flow of liquid from the second tubular member into the first when the sealing disc 26 is flexed for displacement from sealing engagement with the flanged lip 29 of the second tubular member. Again, the rearward end portion of the second tubular member is formed with an outwardly extending flanged portion 28 for use as a finger grip, as. will hereinafter be described. The rearward end. of the passage 21 is sealed with a rubber plu 30 mounted for axial displacement through the passage 21 as a piston within the cylinder defined by the second tubular member. Means, such as a threaded stud 31* is provided on the rearward end of the plug type piston for connection of an actuator 32 for displacement of the piston relative the cylinder. In the illustrated modification, the actuator 32 is in the form of a third elongate tubular member dimensioned to have a cross-section less than the cross-section of the passage 21
through the second tubular member and formed at one end with an internally threaded. female portion 33 for threaded engagement onto the threaded plug 31. The rearward end of the actuator is formed with an outwardly- -extending' flanged portion 3 , for use as a finger grip.
.second tubular member to achieve a floating seal between the fluid contained, in the second tubular member and the dry particulate material adapted to be contained in the first casing for admixture with the fluid. For this purpose, there is provided a piston seal in the form of a rubber or rubber-like member 4o having a sealing rib 4l or sealing ribs 4l and 42 dimensioned to correspond with the cross- sectional dimension of the bore of the tubular member slid- ably to engage the inner wall thereof in sealing relation. The sealing ribs represent a continuation of a sealing body ■y ortion 3 having a slit 44 which extends through the central portion thereof and which is normally closed but which can be distorted to open position to enable passage of fluid when the piston 30 is displaced forwardly to pressurize the fluid in the tubular member.
In the specific embodiment illustrated, the sealing member is formed of parallel, spaced sealing ribs 4l and 42 connected by a tubular section 45 of smaller dimension with a crosswise extending deformable member 3 midway between the ends of the tubular member with the slit 44
. formed in the center thereof.
In the assembled relation, illustrated in Pig. 1, fluid 35 is housed in sealing relationship within the second tubular member with the floating sealing disc 40 in the forward end portion thereof while the dry medicant 36 is housed in sealing relationship within the first tubular member 1. The loaded device can be shipped and stored for extended periods of time without deterioration of the ingredients and
-
floating disc kO operates to maintain complete separation between the two chambers whereby the dry medicant material is not exposed to the fluid or moisture of the liquid contained in the second tubular member.
In use, the device is held with the two middle fingers under the flanged member 28 of the second tubular member and the actuator 32 is pressed by the thumb to effec displacement of the plug 3 through the cylindrical passage 21. This operates to place the liquid 35 under pressure which first distorts the member 3 to open the slit H in the piston seal to enable the liquid to flow to the resili-ent closure disc 26 to cause flexure sufficient to unseat the disc and establish communication bet\^een the chambers 21 and 2 through the openings 27 to enable flow of fluid under pressure from the chamber 21 in the second tubular member into the chamber 2 of the first tubular member for admixture with the dry medicant 36. This, intermediate portion is illustrated in Fig. 2. The liquid takes the medicant into solution or suspension, with shaking when necessary, to provide a freshly prepared fluid system ready for administration by injection.
Thereafter or before, the needle cover 1? is removed to expose the needle 7 and to free the tension spring 16 which operates automatically to effect rearward displacement of the needle hub and needle whereby the rearward end portion 11 of the needle is projected through the sealing disc 5 into communication with the chamber 2 containing the mixture of fluid and medicant in the freshly
and without exposure of the freshly prepared solution o suspension by inserting the needle into the vessel or
tissue. For this purpose, the outer casing may be grasped with one hand with the middle fingers beneath the flanged portion 3a. The needle is inserted and the thumb is pressed down onto the actuator which, at the end of its travel in the second tubular member, causes displacement of the second tubular member for movement as a piston through the cylindrical passage 2 of the first tubular member thereby forcibly, to displace the freshly prepared fluid system from the interior of the first tubular member through the needle and into the tissue.
It will be Understood that changes may be made in. the details of construction, arrangement and operation without departing from the spirit of the invention, especially as defined in the following, claims .
Claims (15)
1. A syringe assembly comprising inner and oute tubular members with the inner member having an outer wall-to-wall dimension less than the inner wall-to-wall dimension of the outer tubular member to enable the inner tubular member to be telescoped for relative axial movement within the outer tubular member, a rupturable closure sealing the forward end of the outer tubular member, a flexible closure seated on the forward end of the inner tubular member with sealable passages through said flexible closure to define passages therethrough communicating with the interior of the tubular member when the flexible closure is unseated in response to internal pressure, a piston ring portion on the forward end of the inner tubular member in sliding engagement with the inner walls of the outer tubular member, a piston plug dimensioned slidably to be received within the inner tubular member and means for actuating the piston plug axially relative the inner tubular member, a sealing ring of flexible material within said inner tubular member between said piston plug and sealing closure and dimensioned slidably to engage the inner walls of said inner tubular member in sealing relationship with slit through a central portion thereof which is closed in normal position and open when in distorted position, a hypodermic needle, a holder on the forward end portion o the outer tubular member supporting the needle for movemen between extended and retracted positions with the rearward end of the needle terminating a short distance in advance of the rupturable closure when in extended position to ί
2. A syringe assembly according to claim 1 in which the passage through the flexible closure on the forward end of the inner tubular member is in endwise alignment with end portions of the inner tubular member for abutment to effect a sealin relation therewith when in seated position.
3· A syringe assembly according to the preceding claims 1 and 2 in which the needle automatically moves to retracted position in response to removal of the needle cover comprising means constantly urging the holder towards retracted position and means for operative engagement between the cover and holder to retain the holder in extended position when the cover is in position of use and to release the holder for movement to retracted position in response to release by the cover upon removal.
. A syringe assembly according to the preceding claims in which the inner tubular member is adapted to contain a liquid carrier and in which the outer tubular member is adapted to contain a dry material to be taken up by the liquid carrier when the latter is forced from the inner tubular member into the outer tubular member in response to movement of the piston plug axially in the inner tubular member.
5. A syringe assembly according to the preceding claims in which the piston ring portion on the forward end of the/inner tubular member comprises ring members of rubber- like material in sealing engagement with the outer walls of the inner tubular member and extending into sealing engagement with the inner walls of the outer tubular
6. A syringe assembly according to the precedin claims in which the piston ring portion and flexible closure are of a unitary construction mounted onto the forward end portion of the inner tubular member and in which the means in the flexible sealing closure comprises openings extending through the sealing member in a position offset outwardly from axial alignment with the passage through the inner tubular member.
7- A syringe assembly according to the precedin claims in .which the piston plug within the inner tubular member is formed of rubber-like material having circular ribs dimensioned to extend into sealing engagement with th inner walls of the inner tubular member.
8. A syringe assembly according to the precedin claims which includes means on the rearward end of the piston plug for attachment of an actuator and which includes an elongate actuator' dimensioned to exceed the length of travel of the piston plug through the inner tubular member.
9· A syringe assembly according to claim 8 in which the actuato comprises an elongate rod dimensioned t be received in telescoping relation within the inner tubular member and with means for attachment of the actuator to the piston plug.
10.. A syringe assembly according to the precedin claims which includes flanged members extending radially outwardly from the rearward end portions of the inner and outer tubular members for use as finger grips.
11. A syringe assembly according to the preceding •claims in which the sealing ring comprises a disc member having a central body portion and rim portions of greater thickness than the central body portion.
12. A syringe assembly according to the preceding claims in which the sealing ring comprises a pair of axially spaced rim portions} a tubular portion joining inner areas of said rim portions and a disc portion spanning the tubular portion with the slit therein.
13. A syringe assembly according to the preceding claims which includes a tubular cap member secured at its ^rearward end to the forward end portion of the outer tubular member and having an inturned flanged portion at its forward end with a central opening dimensioned to enable axial displacement of the holder therethrough.
1 . A syringe assembly according to claim 13 in which the needle cover is formed with an outwardly extending flanged portion at its rearward end dimensioned to extend beyond the inturned portion of the cap which provides a stop for the cover in position of use.
15. A syringe assembly according to claim 13 in which the needle holder has an outv/ardly extending flanged portion at its rearward end and in which the means constantly urging the needle holder to retracted position comprises a coil spring between said holder flange and said inturned cap portion. 1β. A syringe assembly according to claim 1 in which the means for operative engagement betvjeen the cover and holder comprises a screw-threaded portion on the outer wall in the forward end of the holder for threaded engagement with a screw-threaded portion on the inner wall of the cover. COH P.0. Box 1169, i d - vi Attorneys for Applicant
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86437669A | 1969-10-07 | 1969-10-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL35336A0 IL35336A0 (en) | 1970-11-30 |
IL35336A true IL35336A (en) | 1973-08-29 |
Family
ID=25343135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL35336A IL35336A (en) | 1969-10-07 | 1970-09-22 | Syringe for injection of freshly mixed liquid-powder |
Country Status (15)
Country | Link |
---|---|
US (1) | US3682174A (en) |
JP (1) | JPS5113954B1 (en) |
BE (1) | BE757195A (en) |
CA (1) | CA955135A (en) |
CH (1) | CH513655A (en) |
DE (1) | DE2046145A1 (en) |
DK (1) | DK128766B (en) |
ES (1) | ES384283A1 (en) |
FR (1) | FR2065031A5 (en) |
GB (1) | GB1285415A (en) |
IL (1) | IL35336A (en) |
NL (1) | NL7014499A (en) |
NO (1) | NO130298B (en) |
SE (1) | SE379637B (en) |
ZA (1) | ZA706371B (en) |
Cited By (1)
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CN102940922A (en) * | 2012-10-30 | 2013-02-27 | 无锡耐思生物科技有限公司 | Mixing pre-filled and sealed injector |
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US3779371A (en) * | 1972-03-13 | 1973-12-18 | W Rovinski | Package of separated materials to be mixed |
US3885710A (en) * | 1973-03-20 | 1975-05-27 | Cohen Milton | Mixing dispenser with a selectively retractable seal to permit intermixing of the ingredients |
US3831816A (en) * | 1973-06-29 | 1974-08-27 | R Pauliukonis | Chemical syringe |
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GB2471304B (en) * | 2009-06-24 | 2013-12-11 | Oval Medical Technologies Ltd | A pre-filled syringe or autoinjector |
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US11471479B2 (en) | 2014-10-01 | 2022-10-18 | Eagle Biologics, Inc. | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
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Family Cites Families (7)
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US2577780A (en) * | 1950-05-09 | 1951-12-11 | Compule Corp | Crowned cupped resilient plug for cylindrical passages |
US2869543A (en) * | 1957-08-23 | 1959-01-20 | Iowa Cooperative Ass | Injector |
US3091240A (en) * | 1958-12-29 | 1963-05-28 | Robert K Mcconnaughey | Hypodermic syringe and ventable closure means |
US3076456A (en) * | 1960-03-07 | 1963-02-05 | Elsie B Hunt | Hypodermic syringe |
US3303846A (en) * | 1963-10-08 | 1967-02-14 | Functional Container Corp | Mixing syringe having separate compartments for incompatible medicaments |
US3401693A (en) * | 1965-10-19 | 1968-09-17 | Milton J. Cohen | Needle-hub assembly for hypodermic syringe |
US3424155A (en) * | 1968-01-24 | 1969-01-28 | Stanley J Sarnoff | Burstable diaphragm seal |
-
0
- BE BE757195D patent/BE757195A/en unknown
-
1969
- 1969-10-07 US US864376A patent/US3682174A/en not_active Expired - Lifetime
-
1970
- 1970-09-15 CA CA093,199A patent/CA955135A/en not_active Expired
- 1970-09-18 DE DE19702046145 patent/DE2046145A1/en active Pending
- 1970-09-18 ZA ZA706371A patent/ZA706371B/en unknown
- 1970-09-22 IL IL35336A patent/IL35336A/en unknown
- 1970-10-02 NL NL7014499A patent/NL7014499A/xx not_active Application Discontinuation
- 1970-10-02 GB GB47025/70A patent/GB1285415A/en not_active Expired
- 1970-10-05 FR FR7035944A patent/FR2065031A5/fr not_active Expired
- 1970-10-05 NO NO03751/70*[A patent/NO130298B/no unknown
- 1970-10-06 DK DK507370AA patent/DK128766B/en unknown
- 1970-10-06 SE SE7013521A patent/SE379637B/xx unknown
- 1970-10-06 ES ES384283A patent/ES384283A1/en not_active Expired
- 1970-10-07 JP JP45088196A patent/JPS5113954B1/ja active Pending
- 1970-10-07 CH CH1491970A patent/CH513655A/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102940922A (en) * | 2012-10-30 | 2013-02-27 | 无锡耐思生物科技有限公司 | Mixing pre-filled and sealed injector |
Also Published As
Publication number | Publication date |
---|---|
GB1285415A (en) | 1972-08-16 |
US3682174A (en) | 1972-08-08 |
ZA706371B (en) | 1971-06-30 |
NO130298B (en) | 1974-08-12 |
BE757195A (en) | 1971-03-16 |
ES384283A1 (en) | 1973-02-16 |
DE2046145A1 (en) | 1971-04-15 |
CA955135A (en) | 1974-09-24 |
CH513655A (en) | 1971-10-15 |
IL35336A0 (en) | 1970-11-30 |
FR2065031A5 (en) | 1971-07-23 |
NL7014499A (en) | 1971-04-13 |
SE379637B (en) | 1975-10-20 |
JPS5113954B1 (en) | 1976-05-06 |
DK128766B (en) | 1974-07-01 |
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