IL330385A - תצמיד נוגדן-פוליפפטיד ושימוש רוקחי בו - Google Patents

תצמיד נוגדן-פוליפפטיד ושימוש רוקחי בו

Info

Publication number
IL330385A
IL330385A IL330385A IL33038526A IL330385A IL 330385 A IL330385 A IL 330385A IL 330385 A IL330385 A IL 330385A IL 33038526 A IL33038526 A IL 33038526A IL 330385 A IL330385 A IL 330385A
Authority
IL
Israel
Prior art keywords
antibody
pharmaceutical use
polypeptide conjugate
conjugate
polypeptide
Prior art date
Application number
IL330385A
Other languages
English (en)
Original Assignee
Jiangsu Hengrui Pharmaceuticals Co Ltd
Shanghai hengrui pharmaceutical co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Pharmaceuticals Co Ltd, Shanghai hengrui pharmaceutical co ltd filed Critical Jiangsu Hengrui Pharmaceuticals Co Ltd
Publication of IL330385A publication Critical patent/IL330385A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
IL330385A 2023-12-29 2024-12-27 תצמיד נוגדן-פוליפפטיד ושימוש רוקחי בו IL330385A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202311853381 2023-12-29
PCT/CN2024/143340 WO2025140617A1 (zh) 2023-12-29 2024-12-27 抗体-多肽偶联物及其医药用途

Publications (1)

Publication Number Publication Date
IL330385A true IL330385A (he) 2026-08-01

Family

ID=96216874

Family Applications (1)

Application Number Title Priority Date Filing Date
IL330385A IL330385A (he) 2023-12-29 2024-12-27 תצמיד נוגדן-פוליפפטיד ושימוש רוקחי בו

Country Status (6)

Country Link
CN (1) CN122341393A (he)
AU (1) AU2024413886A1 (he)
CO (1) CO2026010363A2 (he)
IL (1) IL330385A (he)
TW (1) TW202535467A (he)
WO (1) WO2025140617A1 (he)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220153853A1 (en) 2018-12-21 2022-05-19 Jiangsu Hengrui Medicine Co., Ltd. Bispecific protein
CN114853908B (zh) * 2019-05-16 2024-06-07 浙江道尔生物科技有限公司 一种治疗代谢疾病的融合蛋白
US12054551B2 (en) 2020-07-02 2024-08-06 Sanofi FGFR1/KLB targeting agonistic antigen-binding proteins and conjugates thereof with GLP-1R agonistic peptides
JP2023542295A (ja) * 2020-09-14 2023-10-06 リジェネロン ファーマシューティカルズ,インク. Glp1ペプチド模倣薬を含む抗体薬物複合体及びその使用
CA3211180A1 (en) * 2021-02-22 2022-08-25 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Disaccharide linker, disaccharide-small molecule drug conjugate and sugar chain fixed-point antibody-drug conjugate, and preparation method therefor and use thereof
EP4392137A1 (en) * 2021-08-27 2024-07-03 Versanis Bio, Inc. Combination therapies
WO2023046071A1 (zh) 2021-09-23 2023-03-30 江苏恒瑞医药股份有限公司 抗klb抗体及用途
EP4410307A4 (en) * 2021-09-30 2026-05-06 Jiangsu Hengrui Pharmaceuticals Co Ltd PYRROLO BENZODIAZEPINE DERIVATIVE AND CONJUGATE, PROCESS FOR THEIR PREPARATION AND USE

Also Published As

Publication number Publication date
AU2024413886A1 (en) 2026-07-09
WO2025140617A1 (zh) 2025-07-03
TW202535467A (zh) 2025-09-16
CN122341393A (zh) 2026-07-03
CO2026010363A2 (es) 2026-07-31