IL330154A - תרכובת בעלת טבעת מאוחה, תכשיר רוקחי המכיל אותה, ושימוש בה - Google Patents

תרכובת בעלת טבעת מאוחה, תכשיר רוקחי המכיל אותה, ושימוש בה

Info

Publication number
IL330154A
IL330154A IL330154A IL33015426A IL330154A IL 330154 A IL330154 A IL 330154A IL 330154 A IL330154 A IL 330154A IL 33015426 A IL33015426 A IL 33015426A IL 330154 A IL330154 A IL 330154A
Authority
IL
Israel
Prior art keywords
same
pharmaceutical composition
fused ring
ring compound
compound
Prior art date
Application number
IL330154A
Other languages
English (en)
Inventor
Jiyue Zheng
Guiping Zhang
Jiapeng Li
Kuifeng Wang
Shuilong Tong
Tao Liu
Feihong Ji
Original Assignee
Suzhou Genhouse Bio Co Ltd
Jiyue Zheng
Guiping Zhang
Jiapeng Li
Kuifeng Wang
Shuilong Tong
Tao Liu
Feihong Ji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Genhouse Bio Co Ltd, Jiyue Zheng, Guiping Zhang, Jiapeng Li, Kuifeng Wang, Shuilong Tong, Tao Liu, Feihong Ji filed Critical Suzhou Genhouse Bio Co Ltd
Publication of IL330154A publication Critical patent/IL330154A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL330154A 2023-12-21 2024-12-19 תרכובת בעלת טבעת מאוחה, תכשיר רוקחי המכיל אותה, ושימוש בה IL330154A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202311774491 2023-12-21
PCT/CN2024/140567 WO2025130971A1 (zh) 2023-12-21 2024-12-19 稠环化合物、包含其的药物组合物及其用途

Publications (1)

Publication Number Publication Date
IL330154A true IL330154A (he) 2026-08-01

Family

ID=96136465

Family Applications (1)

Application Number Title Priority Date Filing Date
IL330154A IL330154A (he) 2023-12-21 2024-12-19 תרכובת בעלת טבעת מאוחה, תכשיר רוקחי המכיל אותה, ושימוש בה

Country Status (4)

Country Link
CN (1) CN122477208A (he)
AU (1) AU2024406366A1 (he)
IL (1) IL330154A (he)
WO (1) WO2025130971A1 (he)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4692088A1 (en) * 2023-03-24 2026-02-11 Shanghai Jeyou Pharmaceutical Co., Ltd. Compound acting as wrn helicase inhibitor
WO2025223396A1 (en) * 2024-04-22 2025-10-30 3H Pharmaceuticals Co., Ltd. Fused tricyclic compounds and methods of use thereof
WO2025247335A1 (en) * 2024-05-30 2025-12-04 Allorion Therapeutics Inc Compounds and use thereof as wrn inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5079818B2 (ja) 2006-12-22 2012-11-21 メルク・シャープ・アンド・ドーム・コーポレーション Ｈｃｖおよび関連するウイルス疾患の治療または予防のための４，５−環インドール誘導体
AR125966A1 (es) * 2021-05-26 2023-08-30 Novartis Ag Nuevos compuestos bicíclicos y sus usos
WO2023062575A1 (en) * 2021-10-14 2023-04-20 Ideaya Biosciences, Inc. Cyclic vinyl sulfone compounds as wrn inhibitors
WO2024153244A1 (zh) * 2023-01-20 2024-07-25 南京再明医药有限公司 含氮类化合物
EP4692088A1 (en) * 2023-03-24 2026-02-11 Shanghai Jeyou Pharmaceutical Co., Ltd. Compound acting as wrn helicase inhibitor
AU2024286830A1 (en) * 2023-06-08 2025-12-04 Nimbus Wadjet, Inc. Wrn inhibitors
UY40816A (es) * 2023-07-07 2025-01-15 Nimbus Wadjet Inc Inhibidores de triazolo wrn
WO2025021148A1 (zh) * 2023-07-27 2025-01-30 贝达药业股份有限公司 Wrn抑制剂及其药物组合物和应用

Also Published As

Publication number Publication date
AU2024406366A1 (en) 2026-07-09
WO2025130971A1 (zh) 2025-06-26
CN122477208A (zh) 2026-07-28