IL326819A - מעכבי גורם משלים b ושימושיהם - Google Patents

מעכבי גורם משלים b ושימושיהם

Info

Publication number
IL326819A
IL326819A IL326819A IL32681926A IL326819A IL 326819 A IL326819 A IL 326819A IL 326819 A IL326819 A IL 326819A IL 32681926 A IL32681926 A IL 32681926A IL 326819 A IL326819 A IL 326819A
Authority
IL
Israel
Prior art keywords
inhibitors
complement factor
complement
factor
Prior art date
Application number
IL326819A
Other languages
English (en)
Inventor
Lara C Czabaniuk
Nina Gommermann
Konstanze Hurth
Sebastien Jacquier
Nancy Labbe-Giguere
Kaila Ashley Margrey
Adeline Schoen
Martin Sendzik
Anna Vulpetti
Original Assignee
Novartis Ag
Lara C Czabaniuk
Nina Gommermann
Konstanze Hurth
Sebastien Jacquier
Labbe Giguere Nancy
Kaila Ashley Margrey
Adeline Schoen
Martin Sendzik
Anna Vulpetti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Lara C Czabaniuk, Nina Gommermann, Konstanze Hurth, Sebastien Jacquier, Labbe Giguere Nancy, Kaila Ashley Margrey, Adeline Schoen, Martin Sendzik, Anna Vulpetti filed Critical Novartis Ag
Publication of IL326819A publication Critical patent/IL326819A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL326819A 2023-09-29 2024-09-26 מעכבי גורם משלים b ושימושיהם IL326819A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363586620P 2023-09-29 2023-09-29
PCT/IB2024/059431 WO2025068951A1 (en) 2023-09-29 2024-09-26 Complement factor b inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
IL326819A true IL326819A (he) 2026-04-01

Family

ID=93284092

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326819A IL326819A (he) 2023-09-29 2024-09-26 מעכבי גורם משלים b ושימושיהם

Country Status (6)

Country Link
CN (1) CN121925409A (he)
AR (1) AR133953A1 (he)
AU (1) AU2024351332A1 (he)
IL (1) IL326819A (he)
TW (1) TW202515541A (he)
WO (1) WO2025068951A1 (he)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026008072A1 (zh) * 2024-07-05 2026-01-08 南京正大天晴制药有限公司 补体因子b抑制剂在制备治疗或预防pnh药物中的用途
WO2026008074A1 (zh) * 2024-07-05 2026-01-08 南京正大天晴制药有限公司 补体因子b抑制剂的晶型、其制备方法及用途
WO2026008073A1 (zh) * 2024-07-05 2026-01-08 南京正大天晴制药有限公司 补体因子b抑制剂的剂量组合物
WO2026069246A1 (en) * 2024-09-30 2026-04-02 Novartis Ag Complement factor b inhibitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004078163A2 (en) 2003-02-28 2004-09-16 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
JO3425B1 (ar) 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
EP4650351A1 (en) * 2023-01-09 2025-11-19 Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. Inhibitor of complement factor b

Also Published As

Publication number Publication date
WO2025068951A1 (en) 2025-04-03
AR133953A1 (es) 2025-11-19
TW202515541A (zh) 2025-04-16
AU2024351332A1 (en) 2026-03-05
CN121925409A (zh) 2026-04-24

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