IL326708A - חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן - Google Patents
חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטןInfo
- Publication number
- IL326708A IL326708A IL326708A IL32670826A IL326708A IL 326708 A IL326708 A IL 326708A IL 326708 A IL326708 A IL 326708A IL 32670826 A IL32670826 A IL 32670826A IL 326708 A IL326708 A IL 326708A
- Authority
- IL
- Israel
- Prior art keywords
- thetreatment
- halouracil
- cancer
- nucleic acids
- stranded nucleic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363578033P | 2023-08-22 | 2023-08-22 | |
| PCT/US2024/043317 WO2025043036A2 (en) | 2023-08-22 | 2024-08-22 | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL326708A true IL326708A (he) | 2026-04-01 |
Family
ID=94732764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL326708A IL326708A (he) | 2023-08-22 | 2024-08-22 | חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן |
Country Status (6)
| Country | Link |
|---|---|
| KR (1) | KR20260058839A (he) |
| CN (1) | CN121794381A (he) |
| AU (1) | AU2024329501A1 (he) |
| IL (1) | IL326708A (he) |
| MX (1) | MX2026002118A (he) |
| WO (1) | WO2025043036A2 (he) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2462144C (en) * | 2001-09-28 | 2016-09-20 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Micro-rna molecules |
| WO2010036962A1 (en) * | 2008-09-25 | 2010-04-01 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene |
| KR102502248B1 (ko) * | 2016-11-01 | 2023-02-21 | 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 | 5-할로우라실-변형 마이크로rna 및 암 치료시 그 용도 |
| CN110960683B (zh) * | 2018-09-30 | 2022-05-20 | 百药智达(北京)纳米生物技术有限公司 | 含甲氨蝶呤的药物、其制备方法、药物组合物及其应用 |
| KR20210139237A (ko) * | 2019-03-14 | 2021-11-22 | 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 | 변형된 마이크로rna 및 암 치료에 있어서의 이의 용도 |
-
2024
- 2024-08-22 IL IL326708A patent/IL326708A/he unknown
- 2024-08-22 KR KR1020267008218A patent/KR20260058839A/ko active Pending
- 2024-08-22 AU AU2024329501A patent/AU2024329501A1/en active Pending
- 2024-08-22 CN CN202480057567.4A patent/CN121794381A/zh active Pending
- 2024-08-22 WO PCT/US2024/043317 patent/WO2025043036A2/en active Pending
-
2026
- 2026-02-20 MX MX2026002118A patent/MX2026002118A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20260058839A (ko) | 2026-04-29 |
| MX2026002118A (es) | 2026-04-01 |
| CN121794381A (zh) | 2026-04-03 |
| WO2025043036A2 (en) | 2025-02-27 |
| AU2024329501A1 (en) | 2026-03-05 |
| WO2025043036A3 (en) | 2025-03-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL321227A (he) | ציאנין מומסים במים ושימוש בהן בשיטות ריצוף חומצות גרעין | |
| IL317798A (he) | חלקיקים המכילים rna דו-גדילי ושימושם בחקלאות | |
| AU2003243151A8 (en) | Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer | |
| IL317109A (he) | ננוחלקיקים ליפידים למתן של חומצות גרעין ושיטות לשימוש בהם | |
| IL286334B1 (he) | מיקרו רנ" אים שעברו שינוי והשימוש בהם בטיפול בסרטן | |
| IL299783A (he) | טרנספוזיציה ממוקדת ספציפית לרצף, בחירה ומיון של חומצות גרעין | |
| EP4419687A4 (en) | Conditionally activated nucleic acid constructions and their uses for the treatment of neurological diseases | |
| CA3302092A1 (en) | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer | |
| EP4143336A4 (en) | PSEUDOCOMPLEMENTARY BASES IN GENOTYPING AND NUCLEIC ACID SEQUENCING | |
| IL314724A (he) | דנדרימרים משופרים של דנ" א ושיטות לשימוש בהם | |
| IL314316A (he) | תרכובות והשימוש בהן בטיפול בסרטן | |
| IL327476A (he) | אוליגונוקליוטידים משונים ושיטות לשימוש בהם | |
| IL320559A (he) | שילוב אינטגרציה בתיווך טרנספוזון ואינטגרציה ממוקדת של חומצות גרעין לתאים מארחים | |
| IL319688A (he) | הרכבי sirna ושיטות המכוונות לחומצות גרעין אלפא-סינוקלאין | |
| IL313773A (he) | שימוש באוליגונוקלאוטיד nlrp3 למניעה ו/או טיפול של מחלות דלקתיות | |
| CA3269906A1 (en) | Nucleic acid regulatory elements for gene expression in the muscle and methods of use | |
| CA3269026A1 (en) | Therapeutic nucleic acids and methods of use thereof | |
| HK40086501A (en) | Modified short-interfering rna compositions and their use in the treatment of cancer | |
| ZA202301773B (en) | Snp marker of gp gene and its application in macrobrachium rosenbergii | |
| IL272389A (he) | ערכות המכילות נוגדנים ל–pd–l1 ושימושיהם בתראפיה | |
| CA3277473A1 (en) | Amidinourea derivatives and their use in the treatment of cancer | |
| WO2009050730A3 (en) | Rnai mediated knockdown of numa for cancer therapy | |
| GB202510787D0 (en) | Small activating nucleic acid molecules and uses thereof | |
| CA3308373A1 (en) | Modified oligonucleotides and methods of use thereof | |
| HK40110469A (en) | Methods of placing locked nucleic acids in small interfering rna strands |