IL326708A - חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן - Google Patents

חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן

Info

Publication number
IL326708A
IL326708A IL326708A IL32670826A IL326708A IL 326708 A IL326708 A IL 326708A IL 326708 A IL326708 A IL 326708A IL 32670826 A IL32670826 A IL 32670826A IL 326708 A IL326708 A IL 326708A
Authority
IL
Israel
Prior art keywords
thetreatment
halouracil
cancer
nucleic acids
stranded nucleic
Prior art date
Application number
IL326708A
Other languages
English (en)
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Publication of IL326708A publication Critical patent/IL326708A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
IL326708A 2023-08-22 2024-08-22 חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן IL326708A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363578033P 2023-08-22 2023-08-22
PCT/US2024/043317 WO2025043036A2 (en) 2023-08-22 2024-08-22 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer

Publications (1)

Publication Number Publication Date
IL326708A true IL326708A (he) 2026-04-01

Family

ID=94732764

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326708A IL326708A (he) 2023-08-22 2024-08-22 חומצות גרעין דו-גדיליות מותאמות-5-הלואורציל ושימוש בהן בטיפול בסרטן

Country Status (6)

Country Link
KR (1) KR20260058839A (he)
CN (1) CN121794381A (he)
AU (1) AU2024329501A1 (he)
IL (1) IL326708A (he)
MX (1) MX2026002118A (he)
WO (1) WO2025043036A2 (he)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2462144C (en) * 2001-09-28 2016-09-20 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Micro-rna molecules
WO2010036962A1 (en) * 2008-09-25 2010-04-01 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
KR102502248B1 (ko) * 2016-11-01 2023-02-21 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 5-할로우라실-변형 마이크로rna 및 암 치료시 그 용도
CN110960683B (zh) * 2018-09-30 2022-05-20 百药智达(北京)纳米生物技术有限公司 含甲氨蝶呤的药物、其制备方法、药物组合物及其应用
KR20210139237A (ko) * 2019-03-14 2021-11-22 더 리서치 파운데이션 포 더 스테이트 유니버시티 오브 뉴욕 변형된 마이크로rna 및 암 치료에 있어서의 이의 용도

Also Published As

Publication number Publication date
KR20260058839A (ko) 2026-04-29
MX2026002118A (es) 2026-04-01
CN121794381A (zh) 2026-04-03
WO2025043036A2 (en) 2025-02-27
AU2024329501A1 (en) 2026-03-05
WO2025043036A3 (en) 2025-03-27

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