IL326708A - 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer - Google Patents
5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancerInfo
- Publication number
- IL326708A IL326708A IL326708A IL32670826A IL326708A IL 326708 A IL326708 A IL 326708A IL 326708 A IL326708 A IL 326708A IL 32670826 A IL32670826 A IL 32670826A IL 326708 A IL326708 A IL 326708A
- Authority
- IL
- Israel
- Prior art keywords
- thetreatment
- halouracil
- cancer
- nucleic acids
- stranded nucleic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363578033P | 2023-08-22 | 2023-08-22 | |
| PCT/US2024/043317 WO2025043036A2 (en) | 2023-08-22 | 2024-08-22 | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL326708A true IL326708A (en) | 2026-04-01 |
Family
ID=94732764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL326708A IL326708A (en) | 2023-08-22 | 2024-08-22 | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN121794381A (en) |
| AU (1) | AU2024329501A1 (en) |
| IL (1) | IL326708A (en) |
| WO (1) | WO2025043036A2 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2390331B1 (en) * | 2001-09-28 | 2018-04-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | MicroRNA molecules |
| CA2739170A1 (en) * | 2008-09-25 | 2010-04-01 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene |
| JP7130639B2 (en) * | 2016-11-01 | 2022-09-05 | ザ・リサーチ・ファウンデーション・フォー・ザ・ステイト・ユニヴァーシティ・オブ・ニューヨーク | 5-Halouracil-Modified MicroRNAs and Their Use in Treating Cancer |
| CN110960683B (en) * | 2018-09-30 | 2022-05-20 | 百药智达（北京）纳米生物技术有限公司 | Medicine containing methotrexate, preparation method thereof, pharmaceutical composition and application thereof |
| EP3937980A4 (en) * | 2019-03-14 | 2023-08-02 | The Research Foundation for The State University of New York | Modified micrornas and their use in the treatment of cancer |
-
2024
- 2024-08-22 IL IL326708A patent/IL326708A/en unknown
- 2024-08-22 WO PCT/US2024/043317 patent/WO2025043036A2/en active Pending
- 2024-08-22 CN CN202480057567.4A patent/CN121794381A/en active Pending
- 2024-08-22 AU AU2024329501A patent/AU2024329501A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025043036A3 (en) | 2025-03-27 |
| AU2024329501A1 (en) | 2026-03-05 |
| CN121794381A (en) | 2026-04-03 |
| WO2025043036A2 (en) | 2025-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11202107922QA (en) | Closed-ended dna (cedna) and use in methods of reducing gene or nucleic acid therapy related immune response | |
| IL321227A (en) | Water soluble cyanine derivatives and their use in methods of sequencing of nucleic acids | |
| SI1576132T1 (en) | Nucleic acids entitled 273p4b7 and their use in detection of cancer | |
| IL283149A (en) | Inhibitors of HPK1 and their use in the treatment of cancer | |
| IL317798A (en) | Particles comprising double stranded rna and use of same in agriculture | |
| IL317109A (en) | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof | |
| IL286334B1 (en) | Modified micrornas and their use in the treatment of cancer | |
| EP1622571A4 (en) | Nucleic acids and corresponding proteins entitled 109p1d4 useful in treatment and detection of cancer | |
| EP4419687A4 (en) | State-activatable nucleic acid constructs and their uses in the treatment of neurological diseases | |
| IL326708A (en) | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer | |
| CA3302092A1 (en) | 5-halouracil-modified double-stranded nucleic acids and their use in thetreatment of cancer | |
| EP4143336A4 (en) | Pseudo-complementary bases in genotyping and nucleic acid sequencing | |
| IL314724A (en) | Enhanced dna dendrimers and methods of use thereof | |
| IL314316A (en) | Compounds and their use in treating cancer | |
| IL320559A (en) | Combined transposon-mediated integration and targeted integration of nucleic acids into host cells | |
| GB202304914D0 (en) | Nucleic acid molecule and methods | |
| IL313773A (en) | Nlrp3 oligonucleotide for use in preventing and/or treating an inflammatory disease | |
| CA3269906A1 (en) | Nucleic acid regulatory elements for gene expression in the muscle and methods of use | |
| CA3269026A1 (en) | Therapeutic nucleic acids and methods of use thereof | |
| HK40061299A (en) | Close-ended dna (cedna) and use in methods of reducing gene or nucleic acid therapy related immune response | |
| HK40086501A (en) | Modified short-interfering rna compositions and their use in the treatment of cancer | |
| IL272389A (en) | Articles of manufacture comprising anti pd-l1 antibodies and their use in therapy | |
| ZA202205568B (en) | Identification and function of pbragp1 functional gene in pear | |
| GB202510787D0 (en) | Small activating nucleic acid molecules and uses thereof | |
| Norifumi et al. | Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome |