IL326499A - נוגדנים הקושרים btn3a1 ושימושם - Google Patents

נוגדנים הקושרים btn3a1 ושימושם

Info

Publication number
IL326499A
IL326499A IL326499A IL32649926A IL326499A IL 326499 A IL326499 A IL 326499A IL 326499 A IL326499 A IL 326499A IL 32649926 A IL32649926 A IL 32649926A IL 326499 A IL326499 A IL 326499A
Authority
IL
Israel
Prior art keywords
btn3a1
antibodies binding
antibodies
binding
binding btn3a1
Prior art date
Application number
IL326499A
Other languages
English (en)
Inventor
Jun Li
Zeyu Peng
Mingjiu Chen
Original Assignee
Biosion Inc
Jun Li
Zeyu Peng
Mingjiu Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosion Inc, Jun Li, Zeyu Peng, Mingjiu Chen filed Critical Biosion Inc
Publication of IL326499A publication Critical patent/IL326499A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL326499A 2023-08-31 2024-08-30 נוגדנים הקושרים btn3a1 ושימושם IL326499A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363535618P 2023-08-31 2023-08-31
PCT/CN2024/115788 WO2025045192A1 (en) 2023-08-31 2024-08-30 Antibodies binding btn3a1 and uses thereof

Publications (1)

Publication Number Publication Date
IL326499A true IL326499A (he) 2026-04-01

Family

ID=94818171

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326499A IL326499A (he) 2023-08-31 2024-08-30 נוגדנים הקושרים btn3a1 ושימושם

Country Status (5)

Country Link
CN (1) CN121843959A (he)
AU (1) AU2024335446A1 (he)
IL (1) IL326499A (he)
MX (1) MX2026002405A (he)
WO (1) WO2025045192A1 (he)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105457024B (zh) * 2014-10-13 2021-03-16 李小彦 抗butyrophilin-3人源化抗体及其使用
JP7649744B2 (ja) * 2018-12-26 2025-03-21 イムチェック セラピューティクス エスエーエス Ｂｔｎ３ａ結合タンパク質及びその使用
US20220273713A1 (en) * 2019-06-28 2022-09-01 The University Of Melbourne Method of inhibiting or activating gamma delta t cells
EP4288074A4 (en) * 2021-02-08 2025-04-30 The Regents of University of California Regulation of butvrophilin subfamily 3 member a1 (btn3a1, cd277)

Also Published As

Publication number Publication date
WO2025045192A1 (en) 2025-03-06
MX2026002405A (es) 2026-04-01
CN121843959A (zh) 2026-04-10
AU2024335446A1 (en) 2026-01-22

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