IL326355A - Crystalline form of 5-((3r,5s)-3-amino-5-trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile - Google Patents

Crystalline form of 5-((3r,5s)-3-amino-5-trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile

Info

Publication number
IL326355A
IL326355A IL326355A IL32635526A IL326355A IL 326355 A IL326355 A IL 326355A IL 326355 A IL326355 A IL 326355A IL 32635526 A IL32635526 A IL 32635526A IL 326355 A IL326355 A IL 326355A
Authority
IL
Israel
Prior art keywords
carbonitrile
piperidin
quinoline
trifluoromethyl
amino
Prior art date
Application number
IL326355A
Other languages
Hebrew (he)
Inventor
Sylvia Schmidt
Michael Lange
Original Assignee
Merck Patent Gmbh
Sylvia Schmidt
Michael Lange
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Sylvia Schmidt, Michael Lange filed Critical Merck Patent Gmbh
Priority claimed from PCT/EP2024/072516 external-priority patent/WO2025032197A1/en
Publication of IL326355A publication Critical patent/IL326355A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
IL326355A 2023-08-09 2024-08-08 Crystalline form of 5-((3r,5s)-3-amino-5-trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile IL326355A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23190665 2023-08-09
EP23190662 2023-08-09
PCT/EP2024/072516 WO2025032197A1 (en) 2023-08-09 2024-08-08 Crystalline form of 5-((3r,5s)-3-amino-5-trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile

Publications (1)

Publication Number Publication Date
IL326355A true IL326355A (en) 2026-04-01

Family

ID=99138879

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326355A IL326355A (en) 2023-08-09 2024-08-08 Crystalline form of 5-((3r,5s)-3-amino-5-trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile

Country Status (5)

Country Link
KR (1) KR20260049624A (en)
CN (1) CN121773097A (en)
AU (1) AU2024323076A1 (en)
IL (1) IL326355A (en)
MX (1) MX2026001456A (en)

Also Published As

Publication number Publication date
MX2026001456A (en) 2026-03-02
CN121773097A (en) 2026-03-31
KR20260049624A (en) 2026-04-14
AU2024323076A1 (en) 2026-03-26

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