IL326346A - צורה גבישית a1 של 5-((55,3r)-3-אמינו-5-טריפלואורומתיל-פיפרידין-1-יל)-כינולין-8-קרבוניטריל הידרוכלוריד - Google Patents

צורה גבישית a1 של 5-((55,3r)-3-אמינו-5-טריפלואורומתיל-פיפרידין-1-יל)-כינולין-8-קרבוניטריל הידרוכלוריד

Info

Publication number
IL326346A
IL326346A IL326346A IL32634626A IL326346A IL 326346 A IL326346 A IL 326346A IL 326346 A IL326346 A IL 326346A IL 32634626 A IL32634626 A IL 32634626A IL 326346 A IL326346 A IL 326346A
Authority
IL
Israel
Prior art keywords
piperidin
quinoline
trifluoromethyl
amino
crystalline form
Prior art date
Application number
IL326346A
Other languages
English (en)
Inventor
Sylvia Schmidt
Harald Untenecker
Original Assignee
Merck Patent Gmbh
Sylvia Schmidt
Harald Untenecker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Sylvia Schmidt, Harald Untenecker filed Critical Merck Patent Gmbh
Publication of IL326346A publication Critical patent/IL326346A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
IL326346A 2023-08-09 2024-08-08 צורה גבישית a1 של 5-((55,3r)-3-אמינו-5-טריפלואורומתיל-פיפרידין-1-יל)-כינולין-8-קרבוניטריל הידרוכלוריד IL326346A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23190662 2023-08-09
PCT/EP2024/072504 WO2025032190A1 (en) 2023-08-09 2024-08-08 Crystalline form a1 of 5-((3r,55)-3-amino-5- trifluoromethyl-piperidin-1-yl)-quinoline-8-carbonitrile hcl

Publications (1)

Publication Number Publication Date
IL326346A true IL326346A (he) 2026-04-01

Family

ID=87567256

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326346A IL326346A (he) 2023-08-09 2024-08-08 צורה גבישית a1 של 5-((55,3r)-3-אמינו-5-טריפלואורומתיל-פיפרידין-1-יל)-כינולין-8-קרבוניטריל הידרוכלוריד

Country Status (5)

Country Link
KR (1) KR20260049277A (he)
CN (1) CN121843928A (he)
AU (1) AU2024321551A1 (he)
IL (1) IL326346A (he)
WO (1) WO2025032190A1 (he)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3005766A1 (en) 2015-12-17 2017-06-22 Merck Patent Gmbh Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders

Also Published As

Publication number Publication date
AU2024321551A1 (en) 2026-03-26
KR20260049277A (ko) 2026-04-13
CN121843928A (zh) 2026-04-10
WO2025032190A1 (en) 2025-02-13

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