IL326158A - חומרים המשפיעים על פעילות של תעלת אשלגן ותעלת trpv1 ושימושיהם - Google Patents

חומרים המשפיעים על פעילות של תעלת אשלגן ותעלת trpv1 ושימושיהם

Info

Publication number
IL326158A
IL326158A IL326158A IL32615826A IL326158A IL 326158 A IL326158 A IL 326158A IL 326158 A IL326158 A IL 326158A IL 32615826 A IL32615826 A IL 32615826A IL 326158 A IL326158 A IL 326158A
Authority
IL
Israel
Prior art keywords
channel
modulators
trpv1
potassium
potassium channel
Prior art date
Application number
IL326158A
Other languages
English (en)
Inventor
BELINSON Haim
Raveh Adi
Daniel Brown Alan
SILBERMAN Alon
Original Assignee
Bsense Bio Therapeutics Ltd
BELINSON Haim
Raveh Adi
Daniel Brown Alan
SILBERMAN Alon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bsense Bio Therapeutics Ltd, BELINSON Haim, Raveh Adi, Daniel Brown Alan, SILBERMAN Alon filed Critical Bsense Bio Therapeutics Ltd
Publication of IL326158A publication Critical patent/IL326158A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL326158A 2023-07-26 2024-07-26 חומרים המשפיעים על פעילות של תעלת אשלגן ותעלת trpv1 ושימושיהם IL326158A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363528958P 2023-07-26 2023-07-26
US202463652726P 2024-05-29 2024-05-29
PCT/IL2024/050743 WO2025022405A1 (en) 2023-07-26 2024-07-26 Modulators of a potassium channel and of trpv1 channel and uses thereof

Publications (1)

Publication Number Publication Date
IL326158A true IL326158A (he) 2026-03-01

Family

ID=94374457

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326158A IL326158A (he) 2023-07-26 2024-07-26 חומרים המשפיעים על פעילות של תעלת אשלגן ותעלת trpv1 ושימושיהם

Country Status (2)

Country Link
IL (1) IL326158A (he)
WO (1) WO2025022405A1 (he)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8552200B2 (en) * 2010-10-20 2013-10-08 Gruenenthal Gmbh Substituted 6-amino-nicotinamides as KCNQ2/3 modulators
RU2727179C2 (ru) * 2015-11-06 2020-07-21 Ф. Хоффманн-Ля Рош Аг Производные индолин-2-она
AU2018349376A1 (en) * 2017-10-09 2020-05-07 Ramot At Tel-Aviv University Ltd. Modulators of potassium ion and TRPV1 channels and uses thereof
EP4466261A4 (en) * 2022-01-18 2026-01-07 Bsense Bio Therapeutics Ltd Modulators of a Potassium Channel and a TRPV1 Channel and Their Uses

Also Published As

Publication number Publication date
WO2025022405A1 (en) 2025-01-30

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