IL325432A - מתן טיפוליrna באמצעות חומצות גרעין בצורת טבעת - Google Patents
מתן טיפוליrna באמצעות חומצות גרעין בצורת טבעתInfo
- Publication number
- IL325432A IL325432A IL325432A IL32543225A IL325432A IL 325432 A IL325432 A IL 325432A IL 325432 A IL325432 A IL 325432A IL 32543225 A IL32543225 A IL 32543225A IL 325432 A IL325432 A IL 325432A
- Authority
- IL
- Israel
- Prior art keywords
- delivery
- ring
- nucleic acids
- shaped nucleic
- rna therapeutics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/532—Closed or circular
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363522878P | 2023-06-23 | 2023-06-23 | |
| US202363524009P | 2023-06-29 | 2023-06-29 | |
| PCT/US2024/034985 WO2024263891A2 (en) | 2023-06-23 | 2024-06-21 | Delivery of rna therapeutics using ring-shaped nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL325432A true IL325432A (he) | 2026-02-01 |
Family
ID=93936278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL325432A IL325432A (he) | 2023-06-23 | 2025-12-18 | מתן טיפוליrna באמצעות חומצות גרעין בצורת טבעת |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP4731768A2 (he) |
| JP (1) | JP2026521760A (he) |
| KR (1) | KR20260030126A (he) |
| CN (1) | CN121620594A (he) |
| AU (1) | AU2024312646A1 (he) |
| CL (1) | CL2025004036A1 (he) |
| CO (1) | CO2026000616A2 (he) |
| IL (1) | IL325432A (he) |
| JO (1) | JOP20250321A1 (he) |
| MX (1) | MX2025015413A (he) |
| WO (1) | WO2024263891A2 (he) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2675803B1 (fr) * | 1991-04-25 | 1996-09-06 | Genset Sa | Oligonucleotides fermes, antisens et sens et leurs applications. |
| KR20240082367A (ko) * | 2021-09-23 | 2024-06-10 | 아르네이 사이언시스 엘엘씨 | 치료학적 물질로서 고리형 구조의 올리고뉴클레오티드 |
-
2024
- 2024-06-21 EP EP24826715.5A patent/EP4731768A2/en active Pending
- 2024-06-21 JP JP2025574134A patent/JP2026521760A/ja active Pending
- 2024-06-21 WO PCT/US2024/034985 patent/WO2024263891A2/en not_active Ceased
- 2024-06-21 KR KR1020267002126A patent/KR20260030126A/ko active Pending
- 2024-06-21 CN CN202480051132.9A patent/CN121620594A/zh active Pending
- 2024-06-21 AU AU2024312646A patent/AU2024312646A1/en active Pending
-
2025
- 2025-12-17 MX MX2025015413A patent/MX2025015413A/es unknown
- 2025-12-18 IL IL325432A patent/IL325432A/he unknown
- 2025-12-19 CL CL2025004036A patent/CL2025004036A1/es unknown
- 2025-12-21 JO JOJO/P/2025/0321A patent/JOP20250321A1/ar unknown
-
2026
- 2026-01-22 CO CONC2026/0000616A patent/CO2026000616A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2025015413A (es) | 2026-05-04 |
| WO2024263891A3 (en) | 2025-04-03 |
| JP2026521760A (ja) | 2026-07-01 |
| JOP20250321A1 (ar) | 2025-12-21 |
| KR20260030126A (ko) | 2026-03-05 |
| CL2025004036A1 (es) | 2026-05-15 |
| AU2024312646A1 (en) | 2026-01-08 |
| CO2026000616A2 (es) | 2026-02-13 |
| EP4731768A2 (en) | 2026-04-29 |
| CN121620594A (zh) | 2026-03-06 |
| WO2024263891A2 (en) | 2024-12-26 |
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