IL325422A - תרכובת פיפרידין-2,6-דיון אוקסואיזואינדולינילית חליפית כגורם נוגד סרטן - Google Patents

תרכובת פיפרידין-2,6-דיון אוקסואיזואינדולינילית חליפית כגורם נוגד סרטן

Info

Publication number
IL325422A
IL325422A IL325422A IL32542225A IL325422A IL 325422 A IL325422 A IL 325422A IL 325422 A IL325422 A IL 325422A IL 32542225 A IL32542225 A IL 32542225A IL 325422 A IL325422 A IL 325422A
Authority
IL
Israel
Prior art keywords
oxoisoindolinyl
piperidine
substituted
anticancer agent
dione compound
Prior art date
Application number
IL325422A
Other languages
English (en)
Inventor
Godwin Kwame Kumi
Ashok Vinayak Purandare
Emily Charlotte Cherney
James Aaron Balog
Suresh Babu Vishwa Krishna Penmetsa
Satheesh Kesavan Nair
Bharat Dinkar Shimpukade
Durgarao Kantheti
Original Assignee
Bristol Myers Squibb Co
Godwin Kwame Kumi
Ashok Vinayak Purandare
Emily Charlotte Cherney
James Aaron Balog
Suresh Babu Vishwa Krishna Penmetsa
Satheesh Kesavan Nair
Bharat Dinkar Shimpukade
Durgarao Kantheti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co, Godwin Kwame Kumi, Ashok Vinayak Purandare, Emily Charlotte Cherney, James Aaron Balog, Suresh Babu Vishwa Krishna Penmetsa, Satheesh Kesavan Nair, Bharat Dinkar Shimpukade, Durgarao Kantheti filed Critical Bristol Myers Squibb Co
Publication of IL325422A publication Critical patent/IL325422A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
IL325422A 2023-06-23 2025-12-18 תרכובת פיפרידין-2,6-דיון אוקסואיזואינדולינילית חליפית כגורם נוגד סרטן IL325422A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202311042284 2023-06-23
PCT/US2024/034924 WO2024263853A1 (en) 2023-06-23 2024-06-21 Substituted oxoisoindolinyl piperidine-2,6-dione compound as anticancer agent

Publications (1)

Publication Number Publication Date
IL325422A true IL325422A (he) 2026-02-01

Family

ID=91953739

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325422A IL325422A (he) 2023-06-23 2025-12-18 תרכובת פיפרידין-2,6-דיון אוקסואיזואינדולינילית חליפית כגורם נוגד סרטן

Country Status (7)

Country Link
EP (1) EP4731308A1 (he)
KR (1) KR20260028777A (he)
CN (1) CN121646585A (he)
AU (1) AU2024314878A1 (he)
IL (1) IL325422A (he)
MX (1) MX2025014137A (he)
WO (1) WO2024263853A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025226767A1 (en) * 2024-04-24 2025-10-30 Bristol-Myers Squibb Company Substituted 3-(5-(6-aminopyridin-2-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione compounds for use in the treatment of cancer

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* Cited by examiner, † Cited by third party
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TWI309240B (en) 2004-09-17 2009-05-01 Hoffmann La Roche Anti-ox40l antibodies
AU2006230099B2 (en) 2005-03-25 2012-04-19 Gitr, Inc. GITR binding molecules and uses therefor
PL1879573T3 (pl) 2005-05-10 2013-05-31 Incyte Holdings Corp Modulatory 2,3-dioksygenazy indoloaminy i sposoby ich zastosowania
CN104356236B (zh) 2005-07-01 2020-07-03 E.R.施贵宝&圣斯有限责任公司 抗程序性死亡配体1(pd-l1)的人单克隆抗体
CA2634198C (en) 2005-12-20 2014-06-03 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
ES2444574T3 (es) 2006-09-19 2014-02-25 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de la indolamina 2,3-dioxigenasa
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
EP1987839A1 (en) 2007-04-30 2008-11-05 I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
EP2044949A1 (en) 2007-10-05 2009-04-08 Immutep Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
JP5583592B2 (ja) 2007-11-30 2014-09-03 ニューリンク ジェネティクス コーポレイション Ｉｄｏ阻害剤
AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
AU2009333580B2 (en) 2008-12-09 2016-07-07 Genentech, Inc. Anti-PD-L1 antibodies and their use to enhance T-cell function
EP2473531A4 (en) 2009-09-03 2013-05-01 Merck Sharp & Dohme Anti-gitr antibodies
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JP5998060B2 (ja) 2010-03-04 2016-09-28 マクロジェニクス，インコーポレーテッド Ｂ７−ｈ３と反応性のある抗体、その免疫学的に活性なフラグメントおよびその使用
CN102918061B (zh) 2010-03-05 2016-06-08 霍夫曼-拉罗奇有限公司 针对人csf-1r的抗体及其用途
MX378336B (es) 2010-05-04 2025-03-10 Five Prime Therapeutics Inc Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r).
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HRP20201595T1 (hr) 2011-11-28 2020-12-11 Merck Patent Gmbh Anti-pd-l1 protutijela i njihova uporaba
BR112014012624A2 (pt) 2011-12-15 2018-10-09 F Hoffmann-La Roche Ag anticorpos, composição farmacêutica, ácido nucleico, vetores de expressão, célula hospedeira, método para a produção de um anticorpo recombinante e uso do anticorpo
RU2014136332A (ru) 2012-02-06 2016-03-27 Дженентек, Инк. Композиции и способы применения ингибиторов csf1r
AR090263A1 (es) 2012-03-08 2014-10-29 Hoffmann La Roche Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
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AR091649A1 (es) 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
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Also Published As

Publication number Publication date
CN121646585A (zh) 2026-03-10
EP4731308A1 (en) 2026-04-29
KR20260028777A (ko) 2026-03-04
WO2024263853A1 (en) 2024-12-26
MX2025014137A (es) 2026-01-07
AU2024314878A1 (en) 2026-01-22

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