IL324787A - מונומרי il10 הפוכים - Google Patents

מונומרי il10 הפוכים

Info

Publication number
IL324787A
IL324787A IL324787A IL32478725A IL324787A IL 324787 A IL324787 A IL 324787A IL 324787 A IL324787 A IL 324787A IL 32478725 A IL32478725 A IL 32478725A IL 324787 A IL324787 A IL 324787A
Authority
IL
Israel
Prior art keywords
seq
amino acid
polypeptide
human
monomer
Prior art date
Application number
IL324787A
Other languages
English (en)
Inventor
Andrew Morin
Tatjana Petojevic
Mahalakshmi Ramadass
Bhargavi Jayaraman
Original Assignee
Synthekine Inc
Andrew Morin
Tatjana Petojevic
Mahalakshmi Ramadass
Bhargavi Jayaraman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthekine Inc, Andrew Morin, Tatjana Petojevic, Mahalakshmi Ramadass, Bhargavi Jayaraman filed Critical Synthekine Inc
Publication of IL324787A publication Critical patent/IL324787A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
IL324787A 2023-06-01 2024-05-31 מונומרי il10 הפוכים IL324787A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363505651P 2023-06-01 2023-06-01
PCT/US2024/032147 WO2024249957A2 (en) 2023-06-01 2024-05-31 Il10 inverted monomers

Publications (1)

Publication Number Publication Date
IL324787A true IL324787A (he) 2026-01-01

Family

ID=93658692

Family Applications (1)

Application Number Title Priority Date Filing Date
IL324787A IL324787A (he) 2023-06-01 2024-05-31 מונומרי il10 הפוכים

Country Status (5)

Country Link
KR (1) KR20260034079A (he)
CN (1) CN121666243A (he)
AU (1) AU2024280480C1 (he)
IL (1) IL324787A (he)
WO (1) WO2024249957A2 (he)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020172631A2 (en) * 2019-02-21 2020-08-27 Xencor, Inc. Untargeted and targeted il-10 fc-fusion proteins
EP3795583A1 (en) * 2019-09-19 2021-03-24 Ecole Polytechnique Federale de Lausanne (EPFL) Il10/fc fusion proteins useful as enhancers of immunotherapies
CN115362167A (zh) * 2020-02-06 2022-11-18 百时美施贵宝公司 Il-10及其用途
MX2022014239A (es) * 2020-05-12 2023-02-09 Regeneron Pharma Nuevos agonistas de il10 y metodos para su uso.
CA3195260A1 (en) * 2020-10-29 2022-05-05 Bristol-Myers Squibb Company Fusion proteins for the treatment of disease

Also Published As

Publication number Publication date
KR20260034079A (ko) 2026-03-10
CN121666243A (zh) 2026-03-13
AU2024280480C1 (en) 2026-01-29
WO2024249957A2 (en) 2024-12-05
WO2024249957A3 (en) 2025-03-13
AU2024280480A1 (en) 2025-12-04

Similar Documents

Publication Publication Date Title
US12077594B2 (en) IL2RG binding molecules and methods of use
US12440540B2 (en) IL-2 orthologs and methods of use
WO2022032006A2 (en) Il2rb binding molecules and methods of use
US12291572B2 (en) IL12 receptor synthetic cytokines and methods of use
US20230210951A1 (en) Il2 muteins
AU2022371454A1 (en) Human il-12p40 variants and uses thereof
US20250042966A1 (en) Il10 variants and uses thereof
WO2022032025A1 (en) Ifngr binding synthetic cytokines and methods of use
US12122839B2 (en) IFNGR binding synthetic cytokines and methods of use
AU2024280480C1 (en) Il10 inverted monomers
US20230391891A1 (en) Il28a receptor binding synthetic cytokines and methods of use
AU2024282178A1 (en) Fused il10 polypeptides
WO2022031964A2 (en) Ifngr1 binding molecules and methods of use
WO2022031890A1 (en) Ifngr2 binding molecules and methods of use