IL314984A - Oral PCLX-001 for the treatment of human cancer - Google Patents

Oral PCLX-001 for the treatment of human cancer

Info

Publication number
IL314984A
IL314984A IL314984A IL31498424A IL314984A IL 314984 A IL314984 A IL 314984A IL 314984 A IL314984 A IL 314984A IL 31498424 A IL31498424 A IL 31498424A IL 314984 A IL314984 A IL 314984A
Authority
IL
Israel
Prior art keywords
pclx
oral
treatment
human cancer
cancer
Prior art date
Application number
IL314984A
Other languages
English (en)
Hebrew (he)
Inventor
John Robert Mackey
Neal Maynard Davies
Original Assignee
Pacylex Pharmaceuticals Inc
John Robert Mackey
Neal Maynard Davies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacylex Pharmaceuticals Inc, John Robert Mackey, Neal Maynard Davies filed Critical Pacylex Pharmaceuticals Inc
Publication of IL314984A publication Critical patent/IL314984A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL314984A 2022-03-03 2023-03-03 Oral PCLX-001 for the treatment of human cancer IL314984A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263316153P 2022-03-03 2022-03-03
PCT/CA2023/050281 WO2023164776A1 (en) 2022-03-03 2023-03-03 Oral pclx-001 in the treatment of human cancer

Publications (1)

Publication Number Publication Date
IL314984A true IL314984A (en) 2024-10-01

Family

ID=87882761

Family Applications (1)

Application Number Title Priority Date Filing Date
IL314984A IL314984A (en) 2022-03-03 2023-03-03 Oral PCLX-001 for the treatment of human cancer

Country Status (10)

Country Link
US (1) US20250161299A1 (https=)
EP (1) EP4486344A4 (https=)
JP (1) JP2025507923A (https=)
KR (1) KR20240155234A (https=)
CN (1) CN118829428A (https=)
AU (1) AU2023228703A1 (https=)
CA (1) CA3244234A1 (https=)
IL (1) IL314984A (https=)
MX (1) MX2024010584A (https=)
WO (1) WO2023164776A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025050208A1 (en) * 2023-09-05 2025-03-13 Pacylex Pharmaceuticals Inc. Oral pclx-001 in the treatment of human cancer
CN120361006A (zh) * 2025-05-19 2025-07-25 上海交通大学医学院附属第九人民医院 Nmt1抑制剂及其在制备实体瘤治疗药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110974967B (zh) * 2012-10-30 2023-11-07 厄尔莱克斯制药公司 合成致死与癌症的治疗
JP7539760B2 (ja) * 2015-07-17 2024-08-26 パシレックス・ファーマシューティカルズ・インコーポレイテッド Ｎｍｔ２の後成的なサイレンシング
GB201820660D0 (en) * 2018-12-19 2019-01-30 Imperial Innovations Ltd Cancer treatments
MX2023004341A (es) * 2020-10-20 2023-05-24 Pacylex Pharmaceuticals Inc Uso de inhibidores de n-miristoil transferasa (nmt) en el tratamiento del cancer, trastornos autoinmunes y trastornos inflamatorios.

Also Published As

Publication number Publication date
JP2025507923A (ja) 2025-03-21
CN118829428A (zh) 2024-10-22
WO2023164776A1 (en) 2023-09-07
MX2024010584A (es) 2024-09-06
KR20240155234A (ko) 2024-10-28
AU2023228703A1 (en) 2024-09-12
CA3244234A1 (en) 2023-09-07
EP4486344A4 (en) 2026-03-04
EP4486344A1 (en) 2025-01-08
US20250161299A1 (en) 2025-05-22

Similar Documents

Publication Publication Date Title
IL314984A (en) Oral PCLX-001 for the treatment of human cancer
GB202018667D0 (en) Photodynamic therapy and diagnosis
SMT202500434T1 (it) Sotorasib per l'uso nel trattamento del cancro
GB202018015D0 (en) Composition and methods for the treatment of intestinal cancer
IL308992A (en) Cancer treatment in patients with soluble FR-alpha
PH12022551021A1 (en) Sequential anti-cd19 therapy
GB202317288D0 (en) Pyrrolopyridone derivatives useful in the treatment of cancer
GB202311340D0 (en) Cancer diagnosis and treatment
HUE068708T2 (hu) Gyógyszerkombináció és annak alkalmazása rák kezelésében
HK40096009A (en) Use of medicament in treatment of tumor disease
GB202204185D0 (en) Oral treatment
CA3277473A1 (en) Amidinourea derivatives and their use in the treatment of cancer
IL307475A (en) Oxazepine compounds and their uses in cancer treatment
GB202308150D0 (en) Photodynamic therapy and diagnosis
GB202308146D0 (en) Photodynamic therapy and diagnosis
GB202308145D0 (en) Photodynamic therapy and diagnosis
IL320482A (en) Combination therapy for cancer treatment
HK40096965A (en) Pharmaceutical combination and tumor treatment
CA3276953A1 (en) SYNTHETIC VARIANTS OF THE GANGLIOSIDE NGcGM3 AND ITS USE IN CANCER TREATMENT
GB202305541D0 (en) Novel compounds and their use in therapy
GB202305546D0 (en) Novel compounds and their use in therapy
GB202300802D0 (en) Use of a substance in the treatment of spontaneous cancer
HK40080947A (en) Compositions and methods for use in the treatment of cancer
GB202208164D0 (en) Photodynamic therapy and diagnosis
GB202208161D0 (en) Photodynamic therapy and diagnosis