IL31447A - Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series - Google Patents

Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series

Info

Publication number
IL31447A
IL31447A IL31447A IL3144769A IL31447A IL 31447 A IL31447 A IL 31447A IL 31447 A IL31447 A IL 31447A IL 3144769 A IL3144769 A IL 3144769A IL 31447 A IL31447 A IL 31447A
Authority
IL
Israel
Prior art keywords
compounds
formula
compound
dione
diene
Prior art date
Application number
IL31447A
Other languages
English (en)
Other versions
IL31447A0 (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IL31447A0 publication Critical patent/IL31447A0/xx
Publication of IL31447A publication Critical patent/IL31447A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/20—Light-tight connections for movable optical elements
    • G02B7/22—Extensible connections, e.g. bellows

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
IL31447A 1968-01-19 1969-01-19 Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series IL31447A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3100/68A GB1253831A (en) 1968-01-19 1968-01-19 9alpha,21-DIHALOPREGNANE COMPOUNDS

Publications (2)

Publication Number Publication Date
IL31447A0 IL31447A0 (en) 1969-03-27
IL31447A true IL31447A (en) 1973-11-28

Family

ID=9751941

Family Applications (1)

Application Number Title Priority Date Filing Date
IL31447A IL31447A (en) 1968-01-19 1969-01-19 Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series

Country Status (14)

Country Link
US (1) US3721687A (nl)
BE (1) BE727109A (nl)
BR (1) BR6905681D0 (nl)
CA (1) CA952900A (nl)
CH (2) CH564035A5 (nl)
DK (1) DK126500B (nl)
ES (1) ES362679A1 (nl)
FR (1) FR2000443A1 (nl)
GB (1) GB1253831A (nl)
IE (1) IE33204B1 (nl)
IL (1) IL31447A (nl)
NL (1) NL6900795A (nl)
NO (1) NO132100C (nl)
SE (1) SE350035B (nl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
US4154748A (en) * 1978-01-20 1979-05-15 The Upjohn Company Phosphate catalyzed acylation of steroidal tertiary alcohols
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
US4336200A (en) * 1980-01-31 1982-06-22 The Upjohn Company 17α-Acyloxy-5β-corticoids
EP0057401B1 (en) * 1981-02-02 1984-08-01 Schering Corporation Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them
IT1194178B (it) * 1983-03-29 1988-09-14 Ricerche Steroidi Sirs Spa Soc Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti
ES2078175B1 (es) * 1993-12-31 1996-10-16 Cusi Lab Formulacion farmaceutica conteniendo clobetasona y tobramicina y sus aplicaciones.
US20090304603A1 (en) * 2001-06-15 2009-12-10 Cuticeuticals, Inc. Topical steroid spray with botanic seed oils
US20040022741A1 (en) * 2001-06-15 2004-02-05 Crutchfield Charles E. Topical steroid spray
JP2007504123A (ja) * 2003-08-29 2007-03-01 ランバクシー ラボラトリーズ リミテッド Ｉｖ型ホスホジエステラーゼの阻害剤
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
AU2006305620A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
US20090221664A1 (en) 2005-10-19 2009-09-03 Abhijit Ray Pharmaceutical compositions of muscarinic receptor antagonists
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
WO2008035315A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
EA018670B9 (ru) * 2007-03-14 2014-01-30 Ранбакси Лабораториз Лимитед Производные пиразоло[3,4-в]пиридина в качестве ингибиторов фосфодиэстеразы
WO2008111009A1 (en) * 2007-03-14 2008-09-18 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
US8796248B2 (en) * 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN101812107B (zh) * 2010-04-20 2013-05-01 浙江仙居仙乐药业有限公司 一种合成丙酸氯倍他索的方法
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same

Also Published As

Publication number Publication date
DE1902340B2 (de) 1977-06-08
ES362679A1 (es) 1971-02-01
NO132100C (nl) 1975-09-17
DE1902340A1 (de) 1969-09-11
US3721687A (en) 1973-03-20
CA952900A (en) 1974-08-13
NL6900795A (nl) 1969-07-22
SE350035B (nl) 1972-10-16
GB1253831A (en) 1971-11-17
NO132100B (nl) 1975-06-09
BR6905681D0 (pt) 1973-02-08
IL31447A0 (en) 1969-03-27
IE33204L (en) 1969-07-19
CH564035A5 (nl) 1975-07-15
FR2000443A1 (nl) 1969-09-05
DK126500B (da) 1973-07-23
BE727109A (nl) 1969-07-22
CH564563A5 (nl) 1975-07-31
IE33204B1 (en) 1974-04-17

Similar Documents

Publication Publication Date Title
IL31447A (en) Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series
US3828080A (en) Androstane-17beta-carboxylic acids and processes for the preparation thereof
US3312590A (en) Topically active anti-inflammatory 17-mono- and 17,21-diesters of betamethasone and its 9-chloro-analogs, compositions and use thereof
US4124707A (en) 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor
JPS6360036B2 (nl)
US4172132A (en) 1,3,5(10),6,8,14-19-Nor-pregnahexaenes, their use as anti-psoriatic agents, and pharmaceutical formulations useful therefor
US4036831A (en) Trimethyl siloxane steroid intermediates
US4910192A (en) Topically active steroidal anti-inflammatory agents
US4336200A (en) 17α-Acyloxy-5β-corticoids
US5801165A (en) Antiinflammatory, immunosuppressive and antialleric 16, 17-alkylidioxy-steroids
US3312591A (en) Topical compositions of 17alpha,21-ortho esters of betamethasone having topical anti-inflammatory activity and their use
US4318853A (en) 9β,11β-Epoxy-5β-corticoids
US4024131A (en) 16-Methyl-9α-halo steroid esters, ethers and preparation thereof
US3281415A (en) Steroidal delta16-20 (alpha and beta)-hydroperoxides
EP0001864A1 (en) Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositions containing them
CA1251784A (en) Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments
US3845085A (en) Steroids of the pregnane series
US3930970A (en) Photolysis of alcohol nitrites
US4427591A (en) Reduced A ring-Δ9(11) -corticoids
US3707537A (en) 4-chloro-4,6-diene-6-halo or lower alkyl steroids
GB2089808A (en) 5 alpha - and 5 beta -androstane-17 beta - carboxylates and -thiocarboxylates
US4185101A (en) 1,3,5(10),6,8-19-Nor-pregnapentaenes, their use as anti-psoriatic agents, and pharmaceutical formulations useful therefor
US3933799A (en) 11β-Halo-9,12-unsubstituted-C19 -steroids
US3182075A (en) 17-substituted 19-norpregna-1, 3, 5(10), 6, 8-pentaen-20-ones
US3483236A (en) Method of preparing 16alpha,17alpha-dimethylpregn-20-ones