IL314458A - וריאנטים חלבון z הקושרים לימפופואיטין משתיתי תימי ושימוש רפואי שלהם - Google Patents

וריאנטים חלבון z הקושרים לימפופואיטין משתיתי תימי ושימוש רפואי שלהם

Info

Publication number
IL314458A
IL314458A IL314458A IL31445824A IL314458A IL 314458 A IL314458 A IL 314458A IL 314458 A IL314458 A IL 314458A IL 31445824 A IL31445824 A IL 31445824A IL 314458 A IL314458 A IL 314458A
Authority
IL
Israel
Prior art keywords
protein
medical use
thymic stromal
stromal lymphopoietin
variants binding
Prior art date
Application number
IL314458A
Other languages
English (en)
Original Assignee
Affibody Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affibody Ab filed Critical Affibody Ab
Publication of IL314458A publication Critical patent/IL314458A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL314458A 2022-02-08 2023-02-08 וריאנטים חלבון z הקושרים לימפופואיטין משתיתי תימי ושימוש רפואי שלהם IL314458A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22155646 2022-02-08
PCT/EP2023/053030 WO2023152144A1 (en) 2022-02-08 2023-02-08 Protein z variants binding thymic stromal lymphopoietin and their medical use

Publications (1)

Publication Number Publication Date
IL314458A true IL314458A (he) 2024-09-01

Family

ID=80682629

Family Applications (1)

Application Number Title Priority Date Filing Date
IL314458A IL314458A (he) 2022-02-08 2023-02-08 וריאנטים חלבון z הקושרים לימפופואיטין משתיתי תימי ושימוש רפואי שלהם

Country Status (10)

Country Link
EP (1) EP4476247A1 (he)
JP (1) JP2025506381A (he)
KR (1) KR20240139058A (he)
CN (1) CN118632866A (he)
AR (1) AR128475A1 (he)
AU (1) AU2023218534A1 (he)
CA (1) CA3251231A1 (he)
IL (1) IL314458A (he)
MX (1) MX2024009732A (he)
WO (1) WO2023152144A1 (he)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2546261A3 (en) 2007-07-31 2013-08-14 Affibody AB New compositions, methods and use
DK2231860T3 (da) 2007-12-19 2011-12-05 Affibody Ab Polypeptid afledt protein A og i stand til at binde PDGF
KR101884654B1 (ko) 2010-07-09 2018-08-02 애피바디 에이비 폴리펩타이드
KR102123457B1 (ko) 2012-09-25 2020-06-16 애피바디 에이비 알부민 결합 폴리펩타이드
US10669314B2 (en) 2014-06-13 2020-06-02 Affibody Ab Polypeptide
EP3738976B1 (en) * 2015-01-12 2025-07-23 Affibody AB Il-17a-binding fusion protein
ES2773504T3 (es) 2015-10-30 2020-07-13 Affibody Ab Nuevo polipéptido que tiene afinidad por PD-L1
US20220389066A1 (en) * 2019-11-05 2022-12-08 Affibody Ab Polypeptides

Also Published As

Publication number Publication date
CN118632866A (zh) 2024-09-10
KR20240139058A (ko) 2024-09-20
JP2025506381A (ja) 2025-03-11
AU2023218534A1 (en) 2024-07-11
AR128475A1 (es) 2024-05-15
MX2024009732A (es) 2024-08-19
EP4476247A1 (en) 2024-12-18
CA3251231A1 (en) 2023-08-17
WO2023152144A1 (en) 2023-08-17

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