IL31372A - Synergistic antimicrobial compositions containing an organic mercuric salt together with a phenolic compound or an anilide compounds - Google Patents
Synergistic antimicrobial compositions containing an organic mercuric salt together with a phenolic compound or an anilide compoundsInfo
- Publication number
- IL31372A IL31372A IL3137268A IL3137268A IL31372A IL 31372 A IL31372 A IL 31372A IL 3137268 A IL3137268 A IL 3137268A IL 3137268 A IL3137268 A IL 3137268A IL 31372 A IL31372 A IL 31372A
- Authority
- IL
- Israel
- Prior art keywords
- organic
- tho
- antimicrobial
- antimicrobial agent
- compositions containing
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title claims description 9
- 150000003839 salts Chemical class 0.000 title claims description 7
- 239000000203 mixture Substances 0.000 title claims 9
- 150000002989 phenols Chemical class 0.000 title description 2
- -1 anilide compounds Chemical class 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 claims 9
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical group OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 claims 3
- 229960004068 hexachlorophene Drugs 0.000 claims 3
- 229910002651 NO3 Inorganic materials 0.000 claims 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims 1
- 239000012895 dilution Substances 0.000 description 5
- 238000010790 dilution Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- 101000835996 Caenorhabditis elegans Slit homolog 1 protein Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 150000003931 anilides Chemical class 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 125000001153 fluoro group Chemical class F* 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
Synergietlc Antimicrobial an organic mercuric salt together with a phenolic compound or an anilide to the action antimicrobial whic been for this known in the that than In boat that eon hoped for ie an additive effect of tho two that a total which s than of the for A growth of in dilution of and a effective in namely that in a dilution of effect would mom that tho in a dilution than are and in actually achieved ie than tho of tho the tho two to a dilution or oven of than tho additive of a natter of caooe a total co that a of B could result in concentration actually being the it apparent that to the action thereof an of an an of an tho group and It of to of of provide in io tho antimicrobial of certain is oo td of to ac both bacteriostatic and It another of tho peccant invention to provide that can for various to tho of antiseptic and for for for for treatment o tho for Other will bo from a of the of It found that and nitrated and antimicrobial have the unexpected of greatly potentiating the of phenolic d which used in of or c ae as of difluorooalicylanllido and it cannot the potentiated the activity tho tho phenolic potentiates activity of fact that agen arc in accordance the tho of of tho combination in order to either an inhibitory action the or a action of the and lose total to achieve the for too of aad the or the of ton parte of that of to to potentiated of the of illustrated in w decreased inhibitory killing of of present to ho with the to d tho in distilled and in up at 121 for 15 to the to incubating 18 at and ed final in diluted cent on 20 550 culture to tubes of toot of transferred to of solution g of the were for 4 for dilution no it reported as inhibitory to 1 10 10 10 s Oi 10 t 3 4 1 10 Acetate 1 Parte la t for fluorine derivative of 1 1 1 10 Borate 1 Slt 1 to 10 Parte Acetate ί 4 5 X organic and the can in to the potentiated oot of It that phenolic antimicrobial or the b in of about parte inhibition of concentration about 10 of ot above por of Actual potentiation of than d Of mil by of the fact that mercuric toxic than other for t ie reason it ie that bo in ratio i about e o otnor part of t o other to in of invention to the of 100 tho tho tho alcohol and sufficient to 100 e ml lanolins 41 ac 250 Oil in 1 and sake a solution or the lis 4000 to and part 5 of others to modify departing of insufficientOCRQuality
Claims (1)
1. Claims An antimicrobial composition comprising as ooaotive an antimicrobial organic mercuric salt selected from the group consisting of phenylmercuric and morcuric nitrate and and and an antimicrobial agent selected from the group consisting of a mixture of and and a mixture of diflttorosalicylanilide and luorosalicylanilide in a ratio of about 00 parts of said antimicrobial agent por each part of said organic mercuric Composition acoording to claim 1 vherein said antimicrobial agent is hexachlorophene and said organic salt is Composition according to claim 1 wherein said antimicrobial agent is hexachlorophene and said organic morcuric salt is cu Composition according to claim 1 wherein said antimicrobial agent is hexachlorophene and said organic mercuric salt is chloromethoxypropylmercuric Composition according to claim 1 wherein said antimicrobial agent is bithinol and said organic mercuric salt is An antimicrobial composition substantially as hereinbefore described with reference to the For the Applicants Hess insufficientOCRQuality
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL3137268A IL31372A (en) | 1968-01-06 | 1968-01-06 | Synergistic antimicrobial compositions containing an organic mercuric salt together with a phenolic compound or an anilide compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL3137268A IL31372A (en) | 1968-01-06 | 1968-01-06 | Synergistic antimicrobial compositions containing an organic mercuric salt together with a phenolic compound or an anilide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL31372A true IL31372A (en) | 1972-12-29 |
Family
ID=11044767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL3137268A IL31372A (en) | 1968-01-06 | 1968-01-06 | Synergistic antimicrobial compositions containing an organic mercuric salt together with a phenolic compound or an anilide compounds |
Country Status (1)
| Country | Link |
|---|---|
| IL (1) | IL31372A (en) |
-
1968
- 1968-01-06 IL IL3137268A patent/IL31372A/en unknown
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