IL313185A - Peptide inhibitors of the interleukin-23 receptor - Google Patents
Peptide inhibitors of the interleukin-23 receptorInfo
- Publication number
- IL313185A IL313185A IL313185A IL31318524A IL313185A IL 313185 A IL313185 A IL 313185A IL 313185 A IL313185 A IL 313185A IL 31318524 A IL31318524 A IL 31318524A IL 313185 A IL313185 A IL 313185A
- Authority
- IL
- Israel
- Prior art keywords
- nal
- aminomethyl
- leu
- dab
- wqc
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21211815 | 2021-12-01 | ||
| PCT/EP2022/084077 WO2023099669A1 (en) | 2021-12-01 | 2022-12-01 | Peptide inhibitors of interleukin-23 receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL313185A true IL313185A (en) | 2024-07-01 |
Family
ID=78821013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL313185A IL313185A (en) | 2021-12-01 | 2022-12-01 | Peptide inhibitors of the interleukin-23 receptor |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20250154198A1 (https=) |
| EP (1) | EP4440592A1 (https=) |
| JP (1) | JP2024543204A (https=) |
| KR (1) | KR20240111800A (https=) |
| CN (1) | CN118354781A (https=) |
| AU (1) | AU2022402440A1 (https=) |
| CA (1) | CA3240982A1 (https=) |
| CL (1) | CL2024001598A1 (https=) |
| IL (1) | IL313185A (https=) |
| MX (1) | MX2024006556A (https=) |
| TW (1) | TW202332682A (https=) |
| WO (1) | WO2023099669A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4471048A1 (en) | 2023-06-01 | 2024-12-04 | Zealand Pharma A/S | Peptide inhibitors of interleukin-23 receptor |
| EP4471049A1 (en) * | 2023-06-01 | 2024-12-04 | Zealand Pharma A/S | Peptide inhibitors of interleukin-23 receptor |
| CN121794283A (zh) * | 2023-09-08 | 2026-04-03 | 赛诺菲 | 作为选择性il-23受体抑制剂的新型肽 |
| WO2026013260A1 (en) | 2024-07-12 | 2026-01-15 | Zealand Pharma A/S | Peptide inhibitors of interleukin-23 receptor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU723268B2 (en) | 1996-09-09 | 2000-08-24 | Zealand Pharma A/S | Improved solid-phase peptide synthesis and agent for use in such synthesis |
| US8946150B2 (en) | 2011-06-14 | 2015-02-03 | Medical Diagnostic Laboratories, LLC. | Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| MX384213B (es) | 2015-07-15 | 2025-03-14 | Protagonist Therapeutics Inc | Inhibidores peptidicos del receptor de interleucina 23 y su uso para tratar enfermedades inflamatorias. |
| WO2018022937A1 (en) | 2016-07-27 | 2018-02-01 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases |
| WO2018089693A2 (en) | 2016-11-09 | 2018-05-17 | Protagonist Therapeutics, Inc. | Methods for determining and monitoring gastrointestinal inflammation |
| WO2018136646A1 (en) | 2017-01-18 | 2018-07-26 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2020014646A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2021007433A1 (en) | 2019-07-10 | 2021-01-14 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| AU2021209086A1 (en) * | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| CA3167751A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2021146458A1 (en) | 2020-01-15 | 2021-07-22 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
-
2022
- 2022-12-01 AU AU2022402440A patent/AU2022402440A1/en active Pending
- 2022-12-01 EP EP22830694.0A patent/EP4440592A1/en active Pending
- 2022-12-01 IL IL313185A patent/IL313185A/en unknown
- 2022-12-01 JP JP2024532708A patent/JP2024543204A/ja active Pending
- 2022-12-01 US US18/715,410 patent/US20250154198A1/en active Pending
- 2022-12-01 CA CA3240982A patent/CA3240982A1/en active Pending
- 2022-12-01 WO PCT/EP2022/084077 patent/WO2023099669A1/en not_active Ceased
- 2022-12-01 KR KR1020247021622A patent/KR20240111800A/ko active Pending
- 2022-12-01 MX MX2024006556A patent/MX2024006556A/es unknown
- 2022-12-01 CN CN202280079717.2A patent/CN118354781A/zh active Pending
- 2022-12-01 TW TW111146213A patent/TW202332682A/zh unknown
-
2024
- 2024-05-28 CL CL2024001598A patent/CL2024001598A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2024001598A1 (es) | 2024-11-15 |
| MX2024006556A (es) | 2024-06-12 |
| TW202332682A (zh) | 2023-08-16 |
| WO2023099669A1 (en) | 2023-06-08 |
| CA3240982A1 (en) | 2023-06-08 |
| US20250154198A1 (en) | 2025-05-15 |
| AU2022402440A1 (en) | 2024-05-30 |
| CN118354781A (zh) | 2024-07-16 |
| KR20240111800A (ko) | 2024-07-17 |
| JP2024543204A (ja) | 2024-11-19 |
| EP4440592A1 (en) | 2024-10-09 |
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