IL311382A - Drug administration system for local delivery of therapeutic substances and their uses - Google Patents

Drug administration system for local delivery of therapeutic substances and their uses

Info

Publication number
IL311382A
IL311382A IL311382A IL31138224A IL311382A IL 311382 A IL311382 A IL 311382A IL 311382 A IL311382 A IL 311382A IL 31138224 A IL31138224 A IL 31138224A IL 311382 A IL311382 A IL 311382A
Authority
IL
Israel
Prior art keywords
delivery system
drug delivery
therapeutic agents
delivering therapeutic
locally delivering
Prior art date
Application number
IL311382A
Other languages
English (en)
Hebrew (he)
Original Assignee
Coval Biopharma Shanghai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coval Biopharma Shanghai Co Ltd filed Critical Coval Biopharma Shanghai Co Ltd
Publication of IL311382A publication Critical patent/IL311382A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL311382A 2021-09-16 2022-09-14 Drug administration system for local delivery of therapeutic substances and their uses IL311382A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2021118666 2021-09-16
PCT/CN2022/118658 WO2023040879A1 (en) 2021-09-16 2022-09-14 Drug delivery system for locally delivering therapeutic agents and uses thereof

Publications (1)

Publication Number Publication Date
IL311382A true IL311382A (en) 2024-05-01

Family

ID=85602430

Family Applications (1)

Application Number Title Priority Date Filing Date
IL311382A IL311382A (en) 2021-09-16 2022-09-14 Drug administration system for local delivery of therapeutic substances and their uses

Country Status (9)

Country Link
US (1) US20240398963A1 (cg-RX-API-DMAC7.html)
EP (1) EP4402152A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024533034A (cg-RX-API-DMAC7.html)
KR (1) KR20240056728A (cg-RX-API-DMAC7.html)
CN (1) CN118019750A (cg-RX-API-DMAC7.html)
AU (1) AU2022348759A1 (cg-RX-API-DMAC7.html)
CA (1) CA3227319A1 (cg-RX-API-DMAC7.html)
IL (1) IL311382A (cg-RX-API-DMAC7.html)
WO (1) WO2023040879A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026002095A1 (en) * 2024-06-26 2026-01-02 Coval Biopharma (Shanghai) Co., Ltd. Drug delivery system for locally controlled release of therapeutic agents and uses thereof
CN119735627B (zh) * 2024-12-25 2025-10-21 西北农林科技大学 甾体并3,4二氢吡咯吡嗪酮衍生物及其合成方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009096749A (ja) * 2007-10-16 2009-05-07 Konica Minolta Holdings Inc コレステロール誘導体、リポソーム及びx線用造影剤
SG11201609490QA (en) * 2014-05-15 2016-12-29 Agency Science Tech & Res Polymer-flavonoid conjugate and uses thereof
US10350236B2 (en) * 2015-01-09 2019-07-16 Seikagaku Corporation Chondroitin sulfate derivative and agent for treating bladder diseases
SG11202109152UA (en) * 2019-06-03 2021-12-30 Aihol Corp Hyaluronan conjugates and uses thereof
US11458204B2 (en) * 2020-06-02 2022-10-04 Aihol Corporation Method for improving substitution rate and/or substitution efficiency of hyaluronan-drug conjugates
CN117838875B (zh) * 2020-07-15 2025-01-24 上海椿安生物医药科技有限公司 用于局部递送治疗剂的药物递送系统以及其用途

Also Published As

Publication number Publication date
KR20240056728A (ko) 2024-04-30
AU2022348759A1 (en) 2024-01-25
CN118019750A (zh) 2024-05-10
CA3227319A1 (en) 2023-03-23
US20240398963A1 (en) 2024-12-05
EP4402152A1 (en) 2024-07-24
JP2024533034A (ja) 2024-09-12
WO2023040879A1 (en) 2023-03-23
EP4402152A4 (en) 2026-05-20

Similar Documents

Publication Publication Date Title
IL284733A (en) Pharmaceutical delivery compositions and uses thereof
BR112018013245A2 (pt) método e aparelho para administração óxido nítrico com drogas suplementares
IL307997A (en) Pharmaceutical compositions and intravitreal drug delivery systems for the treatment of ocular diseases
CR20210368A (es) Combinación de dextrometorfano y bupropión para el tratamiento de depresión
KR20240101682A9 (ko) 이중특이 항체-캄프토테신 약물 접합체 및 이의 약학적 용도
EP3354306A4 (en) DRUG ADMINISTRATIVE AND DRUG ADMINISTRATION UNIT
NZ750422A (en) Oral gastroretentive formulations and uses thereof
CY1119805T1 (el) Συστημα χορηγησης φαρμακων για τη χορηγηση πτωχως υδατοδιαλυτων φαρμακευτικως ενεργων ουσιων
EP3700617A4 (en) SYSTEMS AND METHODS FOR ADMINISTERING NEUROR-REGENERATIVE THERAPY
EP3962661A4 (en) DEVICES AND METHODS FOR NASAL DRUG OR AGENTS DELIVERY
JOP20240078A1 (ar) تركيبات إردافيتينيب وأنظمة الإعطاء داخل المثانة
IL285073A (en) Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same
EP4181963A4 (en) Drug delivery system for local administration of therapeutic agents and uses thereof
EP3485887A4 (en) INJECTABLE PHARMACEUTICAL COMPOSITION OF TECOVIRIMAT AND PRODUCTION METHOD THEREFOR
IL287912A (en) Pharmaceutical composition of a weak acid drug and methods of administration
EP4402152A4 (en) Drug delivery system for the local administration of therapeutic agents and its uses
TWI925870B (zh) 護理點藥物遞送設備
BR102019016950A2 (pt) forma de dosagem intrauretral de medicamento; e dispositivo
EP4146302A4 (en) DRUG DELIVERY SYSTEM FOR DELIVERY OF ANTIVIRAL AGENTS AND CONTRACEPTIVES
EP4404996A4 (en) PUMP MECHANISM FOR DRUG DELIVERY AND DRUG DELIVERY SYSTEM
BR112018009476A8 (pt) regime de dosagem de plasminogênio para cicatrização de ferimentos
EP3765122A4 (en) MEDICAL INSTRUMENT AND MEDICAL PROCEDURE FOR LOCALIZED ACTIVE SUBSTANCE RELEASE
BR112017022984A2 (pt) dispositivo para facilitar o posicionamento de um cateter para administrar um medicamento em um paciente que esteja respirando espontaneamente
EP4395726A4 (en) CLOSED SYSTEM FOR THE PREPARATION AND ADMINISTRATION OF STERILE MEDICATION
IL313742A (en) A system for administering drugs and methods for using it