IL307677A - An accelerated method for preparing bleached protein formulations - Google Patents

An accelerated method for preparing bleached protein formulations

Info

Publication number
IL307677A
IL307677A IL307677A IL30767723A IL307677A IL 307677 A IL307677 A IL 307677A IL 307677 A IL307677 A IL 307677A IL 30767723 A IL30767723 A IL 30767723A IL 307677 A IL307677 A IL 307677A
Authority
IL
Israel
Prior art keywords
formualtions
accelerated method
lyophilized protein
making lyophilized
making
Prior art date
Application number
IL307677A
Other languages
English (en)
Hebrew (he)
Inventor
Jeff Mccormick
Arnold Mcauley
Original Assignee
Amgen Inc
Jeff Mccormick
Arnold Mcauley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Jeff Mccormick, Arnold Mcauley filed Critical Amgen Inc
Publication of IL307677A publication Critical patent/IL307677A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL307677A 2021-06-01 2022-06-01 An accelerated method for preparing bleached protein formulations IL307677A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163195265P 2021-06-01 2021-06-01
PCT/US2022/031694 WO2022256359A1 (en) 2021-06-01 2022-06-01 Accelerated method of making lyophilized protein formualtions

Publications (1)

Publication Number Publication Date
IL307677A true IL307677A (en) 2023-12-01

Family

ID=82100125

Family Applications (1)

Application Number Title Priority Date Filing Date
IL307677A IL307677A (en) 2021-06-01 2022-06-01 An accelerated method for preparing bleached protein formulations

Country Status (14)

Country Link
US (1) US20240368254A1 (cg-RX-API-DMAC10.html)
EP (1) EP4346778A1 (cg-RX-API-DMAC10.html)
JP (1) JP2024521329A (cg-RX-API-DMAC10.html)
KR (1) KR20240016260A (cg-RX-API-DMAC10.html)
CN (1) CN117241787A (cg-RX-API-DMAC10.html)
AR (1) AR126044A1 (cg-RX-API-DMAC10.html)
AU (1) AU2022285665A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023024757A2 (cg-RX-API-DMAC10.html)
CA (1) CA3217210A1 (cg-RX-API-DMAC10.html)
CL (1) CL2023003443A1 (cg-RX-API-DMAC10.html)
IL (1) IL307677A (cg-RX-API-DMAC10.html)
MX (1) MX2023014034A (cg-RX-API-DMAC10.html)
TW (1) TW202313108A (cg-RX-API-DMAC10.html)
WO (1) WO2022256359A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK4553432T3 (da) 2023-11-08 2026-06-29 Bachem Holding Ag Tørrepose og tørresystem
CN122122428A (zh) 2023-11-08 2026-05-29 巴克姆股份公司 干燥袋和干燥系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
JPH02500329A (ja) 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
AU2001264946A1 (en) 2000-05-24 2001-12-03 Imclone Systems Incorporated Bispecific immunoglobulin-like antigen binding proteins and method of production
EP1786918A4 (en) 2004-07-17 2009-02-11 Imclone Systems Inc NEW BISPECIFIC ANTIBODY TETRAVALENT
CA2697922A1 (en) 2007-08-28 2009-03-12 Biogen Idec Ma Inc. Compositions that bind multiple epitopes of igf-1r
HUE059339T2 (hu) * 2017-09-15 2022-11-28 Amgen Inc Eljárás terápiás fehérje liofilizált gyógyászati kiszerelésére
EP4200333A1 (en) * 2020-08-24 2023-06-28 Amgen Inc. Pharmaceutical formulation comprising a bite, bispecific antibody, and methionine
IL299766A (en) * 2020-09-14 2023-03-01 Amgen Inc Method of making lyophilized protein formulations

Also Published As

Publication number Publication date
JP2024521329A (ja) 2024-05-31
AU2022285665A9 (en) 2023-10-26
TW202313108A (zh) 2023-04-01
EP4346778A1 (en) 2024-04-10
CL2023003443A1 (es) 2024-06-14
CN117241787A (zh) 2023-12-15
WO2022256359A1 (en) 2022-12-08
AR126044A1 (es) 2023-09-06
US20240368254A1 (en) 2024-11-07
KR20240016260A (ko) 2024-02-06
AU2022285665A1 (en) 2023-10-19
BR112023024757A2 (pt) 2024-02-15
CA3217210A1 (en) 2022-12-08
MX2023014034A (es) 2023-12-15

Similar Documents

Publication Publication Date Title
IL308873A (en) Preparations and methods for translation of an improved protein from recombinant circular mRNA
IL287418A (en) Varieties and methods of producing proteins containing them
IL286654A (en) A method for treating mastitis in cattle
GB202105776D0 (en) Engineering of antigen-binding proteins
IL292047A (en) Proteins containing various, multiple unnatural amino acids and methods for preparing and using such proteins
GB2602727B (en) Method of culture
IL317645A (en) Methods for preparing tolbrutinib
GB202303019D0 (en) Method of lyophilisation
IL320231A (en) Antigen-binding protein engineering
GB2592746B (en) Source wafer and method of preparation thereof
IL310595A (en) A standard for determining the glycan profile of proteins
IL286389A (en) A method for treating infective endocarditis
IL308847A (en) The method of recovering a freeze-dried formulation
HK40097519A (en) Method of making lyophilized protein formulations
GB202018320D0 (en) Methods of producing recombinant complement proteins
GB2590625B (en) Method of manufacturing beverage ingredients
SG11202107999PA (en) Protein-containing oral composition and method for improving flavor of protein-containing oral composition
EP4744674A1 (en) GASTRIC ACID-STABLE PROBIOTIC PREPARATION AND ITS PREPARATION PROCESS
GB202107222D0 (en) Method of treg isolation
GB202307533D0 (en) Method of treg isolation
GB202213788D0 (en) Method of lyophilisation
GB202207414D0 (en) Method of treg isolation
GB202007476D0 (en) Method of treg isolation
IL327176A (en) Method for preparing lenifenor
HK40109525A (en) Clostridium chauvoei vaccine and method of making