IL299985A - A method for treating graft-versus-Maschen disease caused by hematopoietic stem cell transplantation - Google Patents

A method for treating graft-versus-Maschen disease caused by hematopoietic stem cell transplantation

Info

Publication number
IL299985A
IL299985A IL299985A IL29998523A IL299985A IL 299985 A IL299985 A IL 299985A IL 299985 A IL299985 A IL 299985A IL 29998523 A IL29998523 A IL 29998523A IL 299985 A IL299985 A IL 299985A
Authority
IL
Israel
Prior art keywords
days
compound
group
administration
use according
Prior art date
Application number
IL299985A
Other languages
English (en)
Hebrew (he)
Inventor
Cheungling Cheng
Yanping Zhao
Hongjun Wang
Weiting Zhong
Jing Li
Jing Zhao
Weina Liu
Original Assignee
Beijing Tide Pharmaceutical Co Ltd
Cheungling Cheng
Yanping Zhao
Hongjun Wang
Weiting Zhong
Jing Li
Jing Zhao
Weina Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Tide Pharmaceutical Co Ltd, Cheungling Cheng, Yanping Zhao, Hongjun Wang, Weiting Zhong, Jing Li, Jing Zhao, Weina Liu filed Critical Beijing Tide Pharmaceutical Co Ltd
Publication of IL299985A publication Critical patent/IL299985A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/4161,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL299985A 2020-07-22 2021-07-21 A method for treating graft-versus-Maschen disease caused by hematopoietic stem cell transplantation IL299985A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010713637 2020-07-22
PCT/CN2021/107575 WO2022017412A1 (zh) 2020-07-22 2021-07-21 治疗造血干细胞移植后的移植物抗宿主病的方法

Publications (1)

Publication Number Publication Date
IL299985A true IL299985A (en) 2023-03-01

Family

ID=79728482

Family Applications (1)

Application Number Title Priority Date Filing Date
IL299985A IL299985A (en) 2020-07-22 2021-07-21 A method for treating graft-versus-Maschen disease caused by hematopoietic stem cell transplantation

Country Status (11)

Country Link
US (1) US20230285393A1 (enExample)
EP (1) EP4186508A4 (enExample)
JP (1) JP7803924B2 (enExample)
KR (1) KR20230043891A (enExample)
CN (2) CN116322670A (enExample)
AU (1) AU2021313124A1 (enExample)
BR (1) BR112023001049A2 (enExample)
CA (1) CA3186564A1 (enExample)
IL (1) IL299985A (enExample)
TW (2) TW202216691A (enExample)
WO (1) WO2022017412A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4393917A4 (en) * 2021-09-18 2025-09-10 Beijing Tide Pharmaceutical Co Ltd SOLID FORM OF A RHO-ASSOCIATED PROTEIN KINASE INHIBITOR OR SOLVATE THEREOF, METHOD OF PREPARATION AND USE THEREOF

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011009568A (es) * 2009-03-09 2011-12-06 Surface Logix Inc Inhibidores de la rho cinasa.
PL2903618T3 (pl) * 2012-10-05 2022-09-19 Kadmon Corporation, Llc Inhibitory kinazy rho
EP3504204A4 (en) * 2016-08-26 2020-05-27 Lycera Corporation INDAZOLYL-L, 2,4-THIADIAZOLAMINE AND RELATED COMPOUNDS FOR INHIBITING RHO-ASSOCIATED PROTEIN KINASES AND FOR TREATING DISEASES
JP7311228B2 (ja) 2017-06-30 2023-07-19 ベイジン タイド ファーマシューティカル カンパニー リミテッド Rho-関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用
CN110582491B (zh) * 2017-06-30 2023-09-29 北京泰德制药股份有限公司 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
KR102563325B1 (ko) 2017-06-30 2023-08-03 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 Rho-관련 단백질 키나아제 억제제, Rho-관련 단백질 키나아제 억제제를 함유하는 약학 조성물, 제조 방법 및 약학 조성물의 용도
TWI881481B (zh) * 2017-08-15 2025-04-21 美商歐米諾斯公司 用於治療和/或預防與造血幹細胞移植有關的移植物抗宿主病和/或瀰漫性肺泡出血和/或靜脈閉塞性病的方法

Also Published As

Publication number Publication date
TWI868660B (zh) 2025-01-01
TW202216691A (zh) 2022-05-01
AU2021313124A1 (en) 2023-03-09
CA3186564A1 (en) 2022-01-27
EP4186508A4 (en) 2024-10-16
EP4186508A1 (en) 2023-05-31
US20230285393A1 (en) 2023-09-14
JP7803924B2 (ja) 2026-01-21
BR112023001049A2 (pt) 2023-03-07
KR20230043891A (ko) 2023-03-31
CN116322670A (zh) 2023-06-23
JP2023535035A (ja) 2023-08-15
WO2022017412A1 (zh) 2022-01-27
TW202327609A (zh) 2023-07-16
CN121846099A (zh) 2026-04-14

Similar Documents

Publication Publication Date Title
US12582653B2 (en) Method for treating idiopathic pulmonary fibrosis
KR102906316B1 (ko) 지방간 질환 및/또는 지방간염의 치료 방법
JP7663508B2 (ja) ジアミノピリミジン化合物を使用することによって、子宮内膜症性疼痛を治療する方法
IL299985A (en) A method for treating graft-versus-Maschen disease caused by hematopoietic stem cell transplantation
EP3960179B1 (en) Method for treating cough by using diaminopyrimidine compound
HK40086216A (en) Method for treating graft versus host disease caused by hematopoietic stem cell transplantation
EP4591863A1 (en) Method for treating pneumoconiosis
HK40064686A (en) Method for treating idiopathic pulmonary fibrosis
HK40062124A (en) Method for treating cough by using diaminopyrimidine compound
HK40058942A (en) Method for treating fatty liver disease and/or steatohepatitis
HK40063173A (en) Method for treating idiopathic pulmonary fibrosis
HK40062123A (en) Method for treating endometriosis-associated pain by using diaminopyrimidine compound