IL299452B1 - Psychoactive alkaloid extraction and composition with controlled dephosphorylation - Google Patents
Psychoactive alkaloid extraction and composition with controlled dephosphorylationInfo
- Publication number
- IL299452B1 IL299452B1 IL299452A IL29945222A IL299452B1 IL 299452 B1 IL299452 B1 IL 299452B1 IL 299452 A IL299452 A IL 299452A IL 29945222 A IL29945222 A IL 29945222A IL 299452 B1 IL299452 B1 IL 299452B1
- Authority
- IL
- Israel
- Prior art keywords
- dephosphorylation
- composition
- controlled
- alkaloid extraction
- psychoactive
- Prior art date
Links
- 229930013930 alkaloid Natural products 0.000 title 1
- 150000003797 alkaloid derivatives Chemical class 0.000 title 1
- 230000030609 dephosphorylation Effects 0.000 title 1
- 238000006209 dephosphorylation reaction Methods 0.000 title 1
- 238000000605 extraction Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0215—Solid material in other stationary receptacles
- B01D11/0253—Fluidised bed of solid materials
- B01D11/0257—Fluidised bed of solid materials using mixing mechanisms, e.g. stirrers, jets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/028—Flow sheets
- B01D11/0284—Multistage extraction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0288—Applications, solvents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0292—Treatment of the solvent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063040317P | 2020-06-17 | 2020-06-17 | |
| US202063046089P | 2020-06-30 | 2020-06-30 | |
| CA3088384A CA3088384C (en) | 2020-06-17 | 2020-07-29 | Extraction of psychoactive compounds from psilocybin fungus |
| CA3089455A CA3089455C (en) | 2020-06-17 | 2020-08-07 | Methanol-based extraction of psychoactive compounds from fungus |
| CA3097246A CA3097246C (en) | 2020-10-23 | 2020-10-23 | Process for obtaining a purified psychoactive alkaloid solution |
| CA3101765A CA3101765A1 (en) | 2020-12-04 | 2020-12-04 | Psychoactive alkaloid extraction and composition with controlled dephosphorylation |
| CA3103707A CA3103707C (en) | 2020-12-18 | 2020-12-18 | Standardized psychoactive alkaloid extract composition |
| PCT/CA2021/050813 WO2021253116A1 (en) | 2020-06-17 | 2021-06-14 | Compositions comprising psychoactive compounds from psychoactive organisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL299452A IL299452A (en) | 2023-02-01 |
| IL299452B1 true IL299452B1 (en) | 2024-09-01 |
Family
ID=79022851
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL299452A IL299452B1 (en) | 2020-06-17 | 2021-06-14 | Psychoactive alkaloid extraction and composition with controlled dephosphorylation |
| IL305632A IL305632A (en) | 2020-06-17 | 2021-06-14 | Extraction of Psychoactive compounds from Psychedelic Fungus |
| IL298561A IL298561A (en) | 2020-06-17 | 2021-06-14 | Methanol-based extraction of psychoactive compounds from fungus |
| IL299451A IL299451B1 (en) | 2020-06-17 | 2021-06-14 | Predominantly phosphorylated psychoactive alkaloid extraction using alkali |
| IL299450A IL299450A (en) | 2020-06-17 | 2021-06-14 | Dephosphorylation-controlled extraction of phosphorylatable psychoactive alkaloids |
| IL299448A IL299448A (en) | 2020-06-17 | 2021-06-14 | Process for Obtaining a Purified Psychoactive Alkaloid Solution |
| IL299453A IL299453B1 (en) | 2020-06-17 | 2021-06-14 | Psychoactive alkaloid extraction and composition with inhibited dephosphorylation |
| IL299449A IL299449A (en) | 2020-06-17 | 2021-06-14 | Standardized Psychoactive Alkaloid Extract Composition |
| IL297791A IL297791A (en) | 2020-06-17 | 2021-06-14 | Compositions comprising psychoactive compounds from psychoactive organisms |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL305632A IL305632A (en) | 2020-06-17 | 2021-06-14 | Extraction of Psychoactive compounds from Psychedelic Fungus |
| IL298561A IL298561A (en) | 2020-06-17 | 2021-06-14 | Methanol-based extraction of psychoactive compounds from fungus |
| IL299451A IL299451B1 (en) | 2020-06-17 | 2021-06-14 | Predominantly phosphorylated psychoactive alkaloid extraction using alkali |
| IL299450A IL299450A (en) | 2020-06-17 | 2021-06-14 | Dephosphorylation-controlled extraction of phosphorylatable psychoactive alkaloids |
| IL299448A IL299448A (en) | 2020-06-17 | 2021-06-14 | Process for Obtaining a Purified Psychoactive Alkaloid Solution |
| IL299453A IL299453B1 (en) | 2020-06-17 | 2021-06-14 | Psychoactive alkaloid extraction and composition with inhibited dephosphorylation |
| IL299449A IL299449A (en) | 2020-06-17 | 2021-06-14 | Standardized Psychoactive Alkaloid Extract Composition |
| IL297791A IL297791A (en) | 2020-06-17 | 2021-06-14 | Compositions comprising psychoactive compounds from psychoactive organisms |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US11331357B2 (en) |
| EP (1) | EP4161546A1 (en) |
| AU (7) | AU2021290454B2 (en) |
| BR (1) | BR112022025780A2 (en) |
| IL (9) | IL299452B1 (en) |
| MX (1) | MX2022016533A (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4038192A4 (en) | 2019-10-01 | 2023-11-01 | Empyrean Neuroscience, Inc. | Genetic engineering of fungi to modulate tryptamine expression |
| CA3113240C (en) | 2020-12-28 | 2023-09-05 | Psilo Scientific Ltd. | Transmucosal psychoactive alkaloid composition and preparation thereof |
| CA3127180C (en) * | 2021-08-06 | 2024-03-05 | Psilo Scientific Ltd. | Pre-evaporation standardization of extracted psychoactive compounds |
| WO2023225186A1 (en) * | 2022-05-18 | 2023-11-23 | Chemtor, Lp | Extraction of psilocybin and psilocin |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE264023C (en) | ||||
| GB911946A (en) | 1958-02-21 | 1962-12-05 | Sandoz Ltd | Psilocybin and psilocin and processes for their preparation |
| LU36879A1 (en) | 1958-02-21 | |||
| DD264023A1 (en) * | 1987-07-17 | 1989-01-18 | Akad Wissenschaften Ddr | PROCESS FOR EXTRACTION OF INDOLALCALOIDS FROM MUSHROOM MATERIAL |
| US6596298B2 (en) | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
| EP1487838B1 (en) | 2002-02-28 | 2008-09-03 | Mallinckrodt Inc. | Method and system for separation and purification of at least one narcotic alkaloid using reverse phase preparative chromatography |
| SE0302947D0 (en) | 2003-01-24 | 2003-11-07 | Magle Ab | A composition material for transmucosal delivery |
| ES2536922T3 (en) | 2006-09-15 | 2015-05-29 | Echo Pharmaceuticals B.V. | Dosing unit for sublingual, oral or oral administration of water-insoluble pharmaceutically active substances |
| CN101292727A (en) | 2008-05-30 | 2008-10-29 | 曹晋忠 | Powder preparing method for mushroom ethyl alcohol extract |
| CN102821791B (en) | 2010-03-30 | 2015-06-17 | 磷肌酸有限公司 | Transdermal delivery patch |
| ES2898173T3 (en) | 2014-06-30 | 2022-03-04 | Syqe Medical Ltd | Devices and systems for the pulmonary administration of active ingredients |
| US20180021326A1 (en) | 2016-07-23 | 2018-01-25 | Paul Edward Stamets | Compositions and methods for enhancing neuroregeneration and cognition by combining mushroom extracts containing active ingredients psilocin or psilocybin with erinacines or hericenones enhanced with niacin |
| NL2018190B1 (en) | 2017-01-18 | 2018-07-26 | Procare Beheer B V | Psilocybin or psilocin in combination with cannabinoid |
| US20190142851A1 (en) * | 2017-11-16 | 2019-05-16 | CaaMTech, LLC | Compositions comprising a psilocybin derivative and a cannabinoid |
| US10933073B2 (en) | 2017-02-09 | 2021-03-02 | Caamtech Llc | Compositions and methods comprising a psilocybin derivative |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CN109528846A (en) * | 2018-12-27 | 2019-03-29 | 贵州理工学院 | A kind of method of Alkaloids in Plants extraction purification |
| EP4219490A1 (en) | 2019-03-07 | 2023-08-02 | Arbormentis LLC | Compositions and methods of use comprising substances with neural plasticity actions administered at non-psychedelic / psychotomimetic dosages and formulations |
| EP3959227A1 (en) | 2019-04-26 | 2022-03-02 | The University of North Carolina at Chapel Hill | Methods and compositions for dual glycan binding aav2.5 vector |
| CA3088384C (en) | 2020-06-17 | 2021-08-03 | Psilo Scientific Ltd. | Extraction of psychoactive compounds from psilocybin fungus |
| CA3097246C (en) | 2020-10-23 | 2023-03-28 | Psilo Scientific Ltd. | Process for obtaining a purified psychoactive alkaloid solution |
| WO2021003467A1 (en) | 2019-07-04 | 2021-01-07 | Sw Holdings, Inc. | Metered dosing compositions and methods of use of psychedelic compounds |
| US11208117B2 (en) | 2019-07-09 | 2021-12-28 | Refraction Ai, Inc. | Method and system for autonomous vehicle control |
| WO2021159213A1 (en) * | 2020-02-12 | 2021-08-19 | Neonmind Biosciences Inc. | Method for producing an extract of mushroom and mushroom extract made therefrom |
| US11382942B2 (en) | 2020-06-17 | 2022-07-12 | Psilo Scientific Ltd. | Extraction of psychoactive compounds from psilocybin fungus |
| US20220054402A1 (en) | 2020-11-05 | 2022-02-24 | Richard C Kaufman | Compositions and methods for extracting, stabilizing, and manufacturing stable dosage forms of psilocin, psychedelic drugs, entheogens, and medicinal mushrooms as nano-dimensional drug delivery structures |
| US20220331292A1 (en) | 2021-04-16 | 2022-10-20 | Callitas Health Inc. | Compositions and methods for delivery of psilocin and prodrugs thereof |
| US20220409584A1 (en) | 2021-06-16 | 2022-12-29 | Intelgenx Corp. | Stable tryptamine oral films |
-
2021
- 2021-06-14 IL IL299452A patent/IL299452B1/en unknown
- 2021-06-14 EP EP21825817.6A patent/EP4161546A1/en active Pending
- 2021-06-14 IL IL305632A patent/IL305632A/en unknown
- 2021-06-14 MX MX2022016533A patent/MX2022016533A/en unknown
- 2021-06-14 AU AU2021290454A patent/AU2021290454B2/en active Active
- 2021-06-14 IL IL298561A patent/IL298561A/en unknown
- 2021-06-14 BR BR112022025780A patent/BR112022025780A2/en unknown
- 2021-06-14 IL IL299451A patent/IL299451B1/en unknown
- 2021-06-14 IL IL299450A patent/IL299450A/en unknown
- 2021-06-14 IL IL299448A patent/IL299448A/en unknown
- 2021-06-14 IL IL299453A patent/IL299453B1/en unknown
- 2021-06-14 IL IL299449A patent/IL299449A/en unknown
- 2021-06-14 IL IL297791A patent/IL297791A/en unknown
- 2021-06-15 US US17/348,697 patent/US11331357B2/en active Active
- 2021-09-23 US US17/483,601 patent/US11298388B2/en active Active
-
2022
- 2022-03-17 US US17/697,798 patent/US11571450B2/en active Active
- 2022-03-23 US US17/702,701 patent/US11642385B2/en active Active
- 2022-12-19 AU AU2022291413A patent/AU2022291413B2/en active Active
- 2022-12-19 AU AU2022291411A patent/AU2022291411B2/en active Active
- 2022-12-19 AU AU2022291410A patent/AU2022291410B2/en active Active
- 2022-12-19 AU AU2022291414A patent/AU2022291414B2/en active Active
- 2022-12-19 AU AU2022291416A patent/AU2022291416B2/en active Active
-
2023
- 2023-12-19 AU AU2023285751A patent/AU2023285751B2/en active Active
Non-Patent Citations (1)
| Title |
|---|
| JABER?VAZDEKIS, NABIL EL, ET AL., STUDIES ON TROPANE ALKALOID EXTRACTION BY VOLATILE ORGANIC SOLVENTS: DICHLOROMETHANE VS. CHLOROFORM., 31 December 2006 (2006-12-31) * |
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