IL297258A - Methods for treating anemia using an actriib ligand trap and fedratinib - Google Patents
Methods for treating anemia using an actriib ligand trap and fedratinibInfo
- Publication number
- IL297258A IL297258A IL297258A IL29725822A IL297258A IL 297258 A IL297258 A IL 297258A IL 297258 A IL297258 A IL 297258A IL 29725822 A IL29725822 A IL 29725822A IL 297258 A IL297258 A IL 297258A
- Authority
- IL
- Israel
- Prior art keywords
- subject
- ligand trap
- actriib ligand
- actriib
- weeks
- Prior art date
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- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Landscapes
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| PCT/US2021/026816 WO2021211418A1 (en) | 2020-04-13 | 2021-04-12 | Methods for treating anemia using an actriib ligand trap and fedratinib |
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| US12186370B1 (en) | 2020-11-05 | 2025-01-07 | Celgene Corporation | ACTRIIB ligand trap compositions and uses thereof |
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| JP2018501307A (ja) * | 2014-12-03 | 2018-01-18 | セルジーン コーポレイション | アクチビン−ＡｃｔＲＩＩアンタゴニスト及び貧血を治療するための使用 |
| PT3286206T (pt) * | 2015-04-22 | 2021-04-01 | Biogen Ma Inc | Novas proteínas híbridas bloqueadoras de ligando actriib para tratar doenças de desgaste muscular |
| CN107847562A (zh) * | 2015-05-13 | 2018-03-27 | 细胞基因公司 | 使用 ACTRII 配体陷阱治疗 β‑地中海贫血 |
| PL3490582T3 (pl) * | 2016-07-27 | 2024-09-23 | Acceleron Pharma Inc. | Kompozycje do zastosowania w leczeniu mielofibrozy |
| WO2018053142A2 (en) * | 2016-09-14 | 2018-03-22 | President And Fellows Of Harvard College | Methods and compositions for modulating erythropoiesis |
| JOP20190085A1 (ar) * | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| HRP20241477T1 (hr) * | 2017-06-14 | 2025-01-03 | Celgene Corporation | Postupci liječenja mijeloproliferativne neoplazme povezane s mijelofibrozom i anemijom |
| KR20210047308A (ko) * | 2018-08-21 | 2021-04-29 | 시에라 온코로지, 인코퍼레이티드 | 골수섬유증을 치료하는 혈소판 수-불특정 방법 |
| EP3856189A4 (en) * | 2018-09-25 | 2022-06-29 | Impact Biomedicines, Inc. | Methods of treating myeloproliferative disorders |
-
2021
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- 2021-04-12 JP JP2022562528A patent/JP2023523568A/ja active Pending
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| EP4135736A1 (en) | 2023-02-22 |
| JP2023523568A (ja) | 2023-06-06 |
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| WO2021211418A1 (en) | 2021-10-21 |
| EP4135736A4 (en) | 2024-06-26 |
| CN115427056A (zh) | 2022-12-02 |
| US20230181690A1 (en) | 2023-06-15 |
| BR112022020628A2 (pt) | 2022-11-29 |
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