IL287025A - Systems and methods to classify antibodies - Google Patents
Systems and methods to classify antibodiesInfo
- Publication number
- IL287025A IL287025A IL287025A IL28702521A IL287025A IL 287025 A IL287025 A IL 287025A IL 287025 A IL287025 A IL 287025A IL 28702521 A IL28702521 A IL 28702521A IL 287025 A IL287025 A IL 287025A
- Authority
- IL
- Israel
- Prior art keywords
- antibodies
- classification
- systems
- methods
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N5/00—Computing arrangements using knowledge-based models
- G06N5/02—Knowledge representation; Symbolic representation
- G06N5/022—Knowledge engineering; Knowledge acquisition
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/30—Detection of binding sites or motifs
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Health & Medical Sciences (AREA)
- Evolutionary Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Data Mining & Analysis (AREA)
- Artificial Intelligence (AREA)
- Software Systems (AREA)
- General Engineering & Computer Science (AREA)
- Evolutionary Computation (AREA)
- Epidemiology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Public Health (AREA)
- Bioethics (AREA)
- Databases & Information Systems (AREA)
- Computational Linguistics (AREA)
- Computing Systems (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Physics (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962831663P | 2019-04-09 | 2019-04-09 | |
| PCT/IB2020/053370 WO2020208555A1 (en) | 2019-04-09 | 2020-04-08 | Systems and methods to classify antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL287025A true IL287025A (en) | 2021-12-01 |
Family
ID=70293015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL287025A IL287025A (en) | 2019-04-09 | 2021-10-06 | Systems and methods to classify antibodies |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220157403A1 (https=) |
| EP (1) | EP3953943A1 (https=) |
| JP (1) | JP7524215B2 (https=) |
| CN (1) | CN113853656A (https=) |
| AU (2) | AU2020271361A1 (https=) |
| CA (1) | CA3132189A1 (https=) |
| IL (1) | IL287025A (https=) |
| WO (1) | WO2020208555A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11049590B1 (en) | 2020-02-12 | 2021-06-29 | Peptilogics, Inc. | Artificial intelligence engine architecture for generating candidate drugs |
| US11403316B2 (en) | 2020-11-23 | 2022-08-02 | Peptilogics, Inc. | Generating enhanced graphical user interfaces for presentation of anti-infective design spaces for selecting drug candidates |
| US11512345B1 (en) | 2021-05-07 | 2022-11-29 | Peptilogics, Inc. | Methods and apparatuses for generating peptides by synthesizing a portion of a design space to identify peptides having non-canonical amino acids |
| WO2022245737A1 (en) * | 2021-05-17 | 2022-11-24 | Genentech, Inc. | Function guided in silico protein design |
| WO2022248935A1 (en) * | 2021-05-27 | 2022-12-01 | Lynceus Sas | Machine learning-based quality control of a culture for bioproduction |
| US11567488B2 (en) * | 2021-05-27 | 2023-01-31 | Lynceus, Sas | Machine learning-based quality control of a culture for bioproduction |
| WO2022271636A1 (en) * | 2021-06-22 | 2022-12-29 | Evqlv, Inc. | Computational characterization and selection of sequence variants |
| WO2023036849A1 (en) * | 2021-09-07 | 2023-03-16 | ETH Zürich | Identifying and predicting future coronavirus variants |
| WO2023049466A2 (en) * | 2021-09-27 | 2023-03-30 | Marwell Bio Inc. | Machine learning for designing antibodies and nanobodies in-silico |
| IL312409A (en) * | 2021-11-01 | 2024-06-01 | Adimab Llc | Systems and methods for intelligent construction of antibody libraries |
| US20230268026A1 (en) * | 2022-01-07 | 2023-08-24 | Absci Corporation | Designing biomolecule sequence variants with pre-specified attributes |
| CN115116543B (zh) * | 2022-04-18 | 2025-08-05 | 腾讯科技（深圳）有限公司 | 抗原抗体结合位点确定方法、装置、设备和存储介质 |
| WO2023215322A1 (en) * | 2022-05-02 | 2023-11-09 | Merck Sharp & Dohme Llc | Generative modeling leveraging deep learning for antibody affinity tuning |
| US12306862B2 (en) * | 2022-05-13 | 2025-05-20 | S&P Global Inc. | Information extraction for unstructured text documents |
| CN115171774A (zh) * | 2022-05-17 | 2022-10-11 | 慧壹科技(上海)有限公司 | 一种抗体/大分子药物的亲和力改造系统和方法 |
| WO2023246834A1 (en) * | 2022-06-24 | 2023-12-28 | King Abdullah University Of Science And Technology | Reinforcement learning (rl) for protein design |
| WO2024040020A1 (en) * | 2022-08-15 | 2024-02-22 | Absci Corporation | Quantitative affinity activity specific cell enrichment |
| CN117672351A (zh) * | 2022-09-01 | 2024-03-08 | 珠海碳云智能科技有限公司 | 一种评估抗体与多肽芯片结合特征的方法 |
| WO2024051806A1 (zh) * | 2022-09-09 | 2024-03-14 | 南京金斯瑞生物科技有限公司 | 一种设计人源化抗体序列的方法 |
| EP4668279A4 (en) | 2023-02-16 | 2026-03-25 | Fujitsu Ltd | INFORMATION PROCESSING PROGRAM, INFORMATION PROCESS, AND INFORMATION PROCESSING DEVICE |
| US12587274B2 (en) | 2023-03-28 | 2026-03-24 | Quantum Generative Materials Llc | Satellite optimization management system based on natural language input and artificial intelligence |
| WO2024208261A1 (zh) * | 2023-04-04 | 2024-10-10 | 南京金斯瑞生物科技有限公司 | 用于抗体药物开发的黏度预测方法 |
| US12531162B1 (en) * | 2023-05-31 | 2026-01-20 | Northeastern University | Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net |
| WO2025070104A1 (ja) * | 2023-09-28 | 2025-04-03 | 富士フイルム株式会社 | 情報処理装置、情報処理装置の作動方法、および情報処理装置の作動プログラム |
| CN117594114B (zh) * | 2023-10-30 | 2024-12-03 | 康复大学(筹) | 一种基于蛋白质结构域预测与生物大分子修饰结合的类抗体的方法 |
| US12562256B2 (en) * | 2023-11-07 | 2026-02-24 | New York University | Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy |
| WO2025128525A1 (en) * | 2023-12-11 | 2025-06-19 | Research Development Foundation | System and method for predicting microproteins |
| US12603701B2 (en) | 2023-12-27 | 2026-04-14 | Quantum Generative Materials Llc | Distributed satellite constellation management and control system |
| US12368503B2 (en) | 2023-12-27 | 2025-07-22 | Quantum Generative Materials Llc | Intent-based satellite transmit management based on preexisting historical location and machine learning |
| US20250279158A1 (en) * | 2024-02-29 | 2025-09-04 | Lurong Pan | Computer-assisted method and system for evaluating and modifying immunogenicity of protein sequences using a protein large language model |
| WO2025235938A1 (en) * | 2024-05-10 | 2025-11-13 | Regeneron Pharmaceuticals, Inc. | Computational methods and systems for predicting developability of protein sequences |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003099999A2 (en) * | 2002-05-20 | 2003-12-04 | Abmaxis, Inc. | Generation and selection of protein library in silico |
| WO2014180490A1 (en) * | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| JP2019513415A (ja) | 2016-04-04 | 2019-05-30 | イーティーエッチ チューリッヒ | タンパク質産生及びライブラリー生成のための哺乳類細胞株 |
| GB201607521D0 (en) * | 2016-04-29 | 2016-06-15 | Oncolmmunity As | Method |
| WO2018132752A1 (en) * | 2017-01-13 | 2018-07-19 | Massachusetts Institute Of Technology | Machine learning based antibody design |
| CN109036580B (zh) | 2018-07-06 | 2021-08-20 | 华东师范大学 | 基于相互作用能项和机器学习的蛋白-配体亲和力预测方法 |
-
2020
- 2020-04-08 WO PCT/IB2020/053370 patent/WO2020208555A1/en not_active Ceased
- 2020-04-08 JP JP2021559527A patent/JP7524215B2/ja active Active
- 2020-04-08 CN CN202080036250.4A patent/CN113853656A/zh active Pending
- 2020-04-08 CA CA3132189A patent/CA3132189A1/en active Pending
- 2020-04-08 EP EP20719736.9A patent/EP3953943A1/en active Pending
- 2020-04-08 US US17/439,374 patent/US20220157403A1/en active Pending
- 2020-04-08 AU AU2020271361A patent/AU2020271361A1/en not_active Abandoned
-
2021
- 2021-10-06 IL IL287025A patent/IL287025A/en unknown
-
2025
- 2025-09-30 AU AU2025242082A patent/AU2025242082A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7524215B2 (ja) | 2024-07-29 |
| CN113853656A (zh) | 2021-12-28 |
| JP2022527381A (ja) | 2022-06-01 |
| EP3953943A1 (en) | 2022-02-16 |
| AU2020271361A1 (en) | 2021-10-28 |
| US20220157403A1 (en) | 2022-05-19 |
| WO2020208555A1 (en) | 2020-10-15 |
| CA3132189A1 (en) | 2020-10-15 |
| AU2025242082A1 (en) | 2025-11-20 |
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