IL286624B2 - Anesthetic preparation and method of eye anesthesia - Google Patents

Anesthetic preparation and method of eye anesthesia

Info

Publication number
IL286624B2
IL286624B2 IL286624A IL28662421A IL286624B2 IL 286624 B2 IL286624 B2 IL 286624B2 IL 286624 A IL286624 A IL 286624A IL 28662421 A IL28662421 A IL 28662421A IL 286624 B2 IL286624 B2 IL 286624B2
Authority
IL
Israel
Prior art keywords
anesthetic preparation
anesthesia
eye
eye anesthesia
anesthetic
Prior art date
Application number
IL286624A
Other languages
Hebrew (he)
Other versions
IL286624A (en
IL286624B1 (en
Inventor
Martin Uram
Original Assignee
Martin Uram
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/024239 external-priority patent/WO2019191200A1/en
Application filed by Martin Uram filed Critical Martin Uram
Publication of IL286624A publication Critical patent/IL286624A/en
Publication of IL286624B1 publication Critical patent/IL286624B1/en
Publication of IL286624B2 publication Critical patent/IL286624B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL286624A 2019-03-26 2020-03-16 Anesthetic preparation and method of eye anesthesia IL286624B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962824207P 2019-03-26 2019-03-26
PCT/US2019/024239 WO2019191200A1 (en) 2018-03-27 2019-03-27 Method and formulation for producing anesthesia of internal aspect of eye wall by topical application
US16/811,798 US11096922B2 (en) 2018-03-27 2020-03-06 Anesthetic composition and method of anesthetizing the eye
PCT/US2020/022915 WO2020197816A1 (en) 2019-03-26 2020-03-16 Anesthetic composition and method of anesthetizing the eye

Publications (3)

Publication Number Publication Date
IL286624A IL286624A (en) 2021-10-31
IL286624B1 IL286624B1 (en) 2026-02-01
IL286624B2 true IL286624B2 (en) 2026-06-01

Family

ID=72609654

Family Applications (2)

Application Number Title Priority Date Filing Date
IL286624A IL286624B2 (en) 2019-03-26 2020-03-16 Anesthetic preparation and method of eye anesthesia
IL325648A IL325648A (en) 2019-03-26 2025-12-28 Anesthetic composition and method of anesthetizing the eye

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL325648A IL325648A (en) 2019-03-26 2025-12-28 Anesthetic composition and method of anesthetizing the eye

Country Status (11)

Country Link
EP (1) EP3946311A4 (en)
JP (1) JP2022527621A (en)
KR (2) KR20210143254A (en)
CN (1) CN114072139A (en)
AU (2) AU2020245203A1 (en)
BR (1) BR112021019039A2 (en)
CA (1) CA3134531A1 (en)
IL (2) IL286624B2 (en)
MX (1) MX2021011589A (en)
SG (1) SG11202110423UA (en)
WO (1) WO2020197816A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003043660A2 (en) * 2001-11-21 2003-05-30 Novartis Ag Composition for stabilizing hyaluronic acid
WO2018220288A1 (en) * 2017-05-29 2018-12-06 Tauzin Benedicte Vincente Sterile injectable composition containing cross-linked hyaluronic acid and articaine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2038580T3 (en) * 1989-08-03 1994-10-16 Eisai Co Ltd PHOTOSTABILIZATION METHOD OF OPHTHALMIC SOLUTIONS.
DE69333850T3 (en) * 1992-05-06 2011-03-17 Alcon Laboratories, Inc., Fort Worth APPLICATION OF BORAL-POLYOL COMPLEXES FOR OPHTHALMIC DRUG COMPOSITIONS
US5972326A (en) * 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2882930B1 (en) * 2005-03-09 2009-03-27 Walid Katib NOVEL OPHTHALMOLOGICAL COMPOSITIONS AND THEIR USE
US20060229219A1 (en) * 2005-04-11 2006-10-12 Advanced Medical Optics, Inc. Borate-polyol mixtures as a buffering system
JP5740906B2 (en) * 2009-10-21 2015-07-01 大正製薬株式会社 Ophthalmic agent
CN101695488B (en) * 2009-11-05 2012-05-02 蚌埠丰原涂山制药有限公司 Compound articaine freeze-dried preparation for injection and preparation method thereof
CN101721407B (en) * 2009-11-23 2013-04-10 蚌埠丰原涂山制药有限公司 Compound articaine hydrochloride injection and preparation method thereof
FR2968996B1 (en) * 2010-12-17 2013-04-12 Anteis Sa AQUEOUS INJECTABLE STERILE FORMULATION USED IN OPHTHALMOLOGY
JP6185725B2 (en) * 2012-02-24 2017-08-23 わかもと製薬株式会社 Aqueous pharmaceutical composition
FR3036035B1 (en) * 2015-05-11 2018-10-05 Laboratoires Vivacy COMPOSITIONS COMPRISING AT LEAST ONE POLYOL AND AT LEAST ONE ANESTHETIC
US20180250313A1 (en) * 2015-09-08 2018-09-06 Viewpoint Therapeutics, Inc. Compounds and formulations for treating ophthalmic diseases
US12414937B2 (en) * 2015-11-05 2025-09-16 University Of Louisville Research Foundation, Inc. Local and regional anesthesia and analgesia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003043660A2 (en) * 2001-11-21 2003-05-30 Novartis Ag Composition for stabilizing hyaluronic acid
WO2018220288A1 (en) * 2017-05-29 2018-12-06 Tauzin Benedicte Vincente Sterile injectable composition containing cross-linked hyaluronic acid and articaine

Also Published As

Publication number Publication date
JP2022527621A (en) 2022-06-02
KR20260110244A (en) 2026-07-14
WO2020197816A1 (en) 2020-10-01
EP3946311A1 (en) 2022-02-09
MX2021011589A (en) 2021-12-15
EP3946311A4 (en) 2022-12-28
CA3134531A1 (en) 2020-10-01
KR20210143254A (en) 2021-11-26
IL286624A (en) 2021-10-31
CN114072139A (en) 2022-02-18
SG11202110423UA (en) 2021-10-28
IL325648A (en) 2026-02-01
IL286624B1 (en) 2026-02-01
AU2025252666A1 (en) 2025-11-06
AU2020245203A1 (en) 2021-11-11
BR112021019039A2 (en) 2021-11-30