IL286285A - נוגדנים קושרי vista ושימושים בהם - Google Patents

נוגדנים קושרי vista ושימושים בהם

Info

Publication number
IL286285A
IL286285A IL286285A IL28628521A IL286285A IL 286285 A IL286285 A IL 286285A IL 286285 A IL286285 A IL 286285A IL 28628521 A IL28628521 A IL 28628521A IL 286285 A IL286285 A IL 286285A
Authority
IL
Israel
Prior art keywords
vista
binding antibodies
antibodies
binding
Prior art date
Application number
IL286285A
Other languages
English (en)
Original Assignee
Xyence Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xyence Therapeutics Inc filed Critical Xyence Therapeutics Inc
Publication of IL286285A publication Critical patent/IL286285A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL286285A 2019-03-12 2021-09-12 נוגדנים קושרי vista ושימושים בהם IL286285A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962817268P 2019-03-12 2019-03-12
PCT/US2020/022461 WO2020186098A1 (en) 2019-03-12 2020-03-12 Vista-binding antibodies and uses thereof

Publications (1)

Publication Number Publication Date
IL286285A true IL286285A (he) 2021-10-31

Family

ID=72428026

Family Applications (1)

Application Number Title Priority Date Filing Date
IL286285A IL286285A (he) 2019-03-12 2021-09-12 נוגדנים קושרי vista ושימושים בהם

Country Status (5)

Country Link
EP (1) EP3976654A1 (he)
JP (1) JP2022525261A (he)
CN (1) CN114729039A (he)
IL (1) IL286285A (he)
WO (1) WO2020186098A1 (he)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105153307A (zh) * 2010-05-04 2015-12-16 梅里麦克制药股份有限公司 抗表皮生长因子受体(egfr)的抗体及其用途
RU2732151C2 (ru) * 2011-09-30 2020-09-11 Чугаи Сейяку Кабусики Кайся Библиотека зависимых от концентрации ионов связывающих молекул
CN108025068A (zh) * 2014-03-12 2018-05-11 耶达研究与开发有限公司 降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤
WO2016207717A1 (en) * 2015-06-24 2016-12-29 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
WO2017175058A1 (en) * 2016-04-07 2017-10-12 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
EP3494141A4 (en) * 2016-08-03 2020-04-08 Bio-Techne Corporation Identification of vsig3/vista as a novel immune checkpoint and use thereof for immunotherapy

Also Published As

Publication number Publication date
JP2022525261A (ja) 2022-05-11
CN114729039A (zh) 2022-07-08
EP3976654A1 (en) 2022-04-06
WO2020186098A1 (en) 2020-09-17

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