IL276639A - Materials and methods for the treatment of dysproliferative diseases - Google Patents
Materials and methods for the treatment of dysproliferative diseasesInfo
- Publication number
- IL276639A IL276639A IL276639A IL27663920A IL276639A IL 276639 A IL276639 A IL 276639A IL 276639 A IL276639 A IL 276639A IL 27663920 A IL27663920 A IL 27663920A IL 276639 A IL276639 A IL 276639A
- Authority
- IL
- Israel
- Prior art keywords
- agents
- treating
- methods
- dysproliferative diseases
- dysproliferative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862632372P | 2018-02-19 | 2018-02-19 | |
| PCT/US2019/018441 WO2019161345A1 (en) | 2018-02-19 | 2019-02-18 | Agents and methods for treating dysproliferative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL276639A true IL276639A (en) | 2020-09-30 |
Family
ID=67619605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL276639A IL276639A (en) | 2018-02-19 | 2020-08-11 | Materials and methods for the treatment of dysproliferative diseases |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US12215090B2 (https=) |
| EP (1) | EP3755693B1 (https=) |
| JP (1) | JP2021513963A (https=) |
| KR (1) | KR20200123184A (https=) |
| CN (1) | CN112351977A (https=) |
| AU (1) | AU2019221837B2 (https=) |
| CA (1) | CA3091642A1 (https=) |
| IL (1) | IL276639A (https=) |
| WO (1) | WO2019161345A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113149942B (zh) * | 2021-02-10 | 2023-06-02 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 一种洛克米兰醇酚羟基衍生物、其制备方法和应用 |
| WO2022221519A1 (en) * | 2021-04-14 | 2022-10-20 | Memorial Sloan-Kettering Cancer Center | Synthetic rocaglates with broad-spectrum antiviral activities and uses thereof |
| CN121712777A (zh) * | 2023-08-18 | 2026-03-20 | 皇家学术促进机构麦吉尔大学 | Rna解旋酶抑制剂 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19934952A1 (de) * | 1998-07-30 | 2000-02-03 | Novartis Ag | Cyclopentabenzofuran-Derivate |
| AUPQ866500A0 (en) | 2000-07-05 | 2000-08-03 | Exgenix Operations Pty Ltd | Therapeutic compounds and methods |
| US7816544B2 (en) | 2004-03-23 | 2010-10-19 | Trustees Of Boston University | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species |
| DE102004024504A1 (de) | 2004-05-18 | 2006-02-16 | Bayer Healthcare Ag | Neue Cylopenta[b]benzofuran-Derivate und ihre Verwendung |
| WO2006007634A1 (en) | 2004-07-16 | 2006-01-26 | Cerylid Biosciences Ltd | Processes and intermediates |
| CA2652873A1 (en) | 2006-05-22 | 2007-12-06 | Trustees Of Boston University | Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral bronsted acids |
| US20100168084A1 (en) | 2008-05-08 | 2010-07-01 | Huber L Julie | Therapeutic compounds and related methods of use |
| EP2189158A1 (en) | 2008-11-20 | 2010-05-26 | DKFZ Deutsches Krebsforschungszentrum, Stiftung des Öffentlichen Rechts | Combination of rocaglamide and apoptosis inducing substances for the treatment of cancer |
| EP2189453A1 (en) | 2008-11-25 | 2010-05-26 | Université Louis Pasteur | Rocaglaol derivatives as cardioprotectant agents |
| WO2011140334A2 (en) * | 2010-05-06 | 2011-11-10 | Trustees Of Boston University | Compounds, methods of making or identifying compounds, and uses thereof |
| US20140255432A1 (en) | 2011-07-27 | 2014-09-11 | Ohio State Innovation Foundation | Silvestrol, silvestrol analogs and uses thereof |
| WO2013170257A1 (en) | 2012-05-11 | 2013-11-14 | Dana-Farber Cancer Institute, Inc. | Treating muc1-expressing cancers with helicase inhibitors |
| WO2015085221A2 (en) | 2013-12-05 | 2015-06-11 | Memorial Sloan Kettering Cancer Center | Methods for identifying anti-cancer compounds |
| JP6306481B2 (ja) | 2014-03-17 | 2018-04-04 | 株式会社神戸製鋼所 | 延性及び曲げ性に優れた高強度冷延鋼板および高強度溶融亜鉛めっき鋼板、並びにそれらの製造方法 |
| FR3023290B1 (fr) * | 2014-07-04 | 2016-08-19 | Pf Medicament | Derives de flavaglines |
| EP3888658B1 (en) * | 2015-11-25 | 2023-12-27 | Effector Therapeutics, Inc. | Eif4-a-inhibiting compounds and methods related thereto |
| US10639378B2 (en) * | 2016-06-06 | 2020-05-05 | Genentech, Inc. | Silvestrol antibody-drug conjugates and methods of use |
-
2019
- 2019-02-18 EP EP19753769.9A patent/EP3755693B1/en active Active
- 2019-02-18 AU AU2019221837A patent/AU2019221837B2/en not_active Expired - Fee Related
- 2019-02-18 JP JP2020543209A patent/JP2021513963A/ja active Pending
- 2019-02-18 WO PCT/US2019/018441 patent/WO2019161345A1/en not_active Ceased
- 2019-02-18 KR KR1020207026863A patent/KR20200123184A/ko not_active Ceased
- 2019-02-18 CA CA3091642A patent/CA3091642A1/en active Pending
- 2019-02-18 CN CN201980025251.6A patent/CN112351977A/zh active Pending
- 2019-02-18 US US16/970,918 patent/US12215090B2/en active Active
-
2020
- 2020-08-11 IL IL276639A patent/IL276639A/en unknown
-
2025
- 2025-02-03 US US19/044,242 patent/US20250361218A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20200392099A1 (en) | 2020-12-17 |
| US12215090B2 (en) | 2025-02-04 |
| EP3755693A4 (en) | 2021-08-04 |
| AU2019221837B2 (en) | 2024-08-01 |
| WO2019161345A1 (en) | 2019-08-22 |
| AU2019221837A1 (en) | 2020-09-03 |
| KR20200123184A (ko) | 2020-10-28 |
| CN112351977A (zh) | 2021-02-09 |
| CA3091642A1 (en) | 2019-08-22 |
| EP3755693A1 (en) | 2020-12-30 |
| JP2021513963A (ja) | 2021-06-03 |
| EP3755693B1 (en) | 2024-06-12 |
| US20250361218A1 (en) | 2025-11-27 |
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