IL271741A - Peptide meters drug with improved pharmaceutical properties - Google Patents
Peptide meters drug with improved pharmaceutical propertiesInfo
- Publication number
- IL271741A IL271741A IL271741A IL27174119A IL271741A IL 271741 A IL271741 A IL 271741A IL 271741 A IL271741 A IL 271741A IL 27174119 A IL27174119 A IL 27174119A IL 271741 A IL271741 A IL 271741A
- Authority
- IL
- Israel
- Prior art keywords
- pro
- pharmaceutical properties
- improved pharmaceutical
- drug peptide
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762526678P | 2017-06-29 | 2017-06-29 | |
| PCT/IB2018/000838 WO2019002945A2 (fr) | 2017-06-29 | 2018-06-29 | Peptide pro-médicament ayant des propriétés pharmaceutiques améliorées |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL271741A true IL271741A (en) | 2020-02-27 |
Family
ID=63684203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL271741A IL271741A (en) | 2017-06-29 | 2019-12-29 | Peptide meters drug with improved pharmaceutical properties |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10889627B2 (fr) |
| EP (1) | EP3645558A2 (fr) |
| JP (1) | JP7046990B2 (fr) |
| KR (1) | KR102398777B1 (fr) |
| CN (1) | CN111051338A (fr) |
| AU (2) | AU2018293467B2 (fr) |
| BR (1) | BR112019028134A2 (fr) |
| CA (1) | CA3067674A1 (fr) |
| IL (1) | IL271741A (fr) |
| SG (1) | SG11201912433YA (fr) |
| WO (1) | WO2019002945A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3911960A1 (fr) | 2019-01-18 | 2021-11-24 | UREKA Sarl | Composés hybrides de peptide-oligourée |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP0561971A1 (fr) * | 1990-12-13 | 1993-09-29 | PHARMACIA & UPJOHN COMPANY | Polypeptides de fusion |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| WO1999046283A1 (fr) * | 1998-03-09 | 1999-09-16 | Zealand Pharmaceuticals A/S | Conjugues peptidiques pharmacologiquement actifs ayant une tendance reduite a l'hydrolyse enzymatique |
| GB0310593D0 (en) * | 2003-05-08 | 2003-06-11 | Leuven K U Res & Dev | Peptidic prodrugs |
| EP2390264A1 (fr) * | 2005-02-11 | 2011-11-30 | Amylin Pharmaceuticals Inc. | Analogues de GIP et polypeptides hybrides de GIP aux propriétés sélectionnables |
| EP1959986B1 (fr) * | 2005-11-07 | 2014-07-23 | Indiana University Research and Technology Corporation | Analogues de glucagon a solubilite et a stabilite physiologiques ameliorees |
| FR2900341B1 (fr) * | 2006-04-27 | 2012-09-14 | Centre Nat Rech Scient | Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer |
| JP2010536341A (ja) * | 2007-08-15 | 2010-12-02 | アムニクス， インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
| US8084597B2 (en) * | 2007-11-15 | 2011-12-27 | Molecular Kinetics Incorporated | Artificial entropic bristle domain sequences and their use in recombinant protein production |
| WO2010080578A1 (fr) * | 2008-12-18 | 2010-07-15 | Phasebio Pharmaceuticals, Inc. | Protéines biologiquement actives pouvant être activées par peptidase |
| US20130053310A1 (en) * | 2010-03-26 | 2013-02-28 | Novo Nordisk A/S | Novel glucagon analogues |
| EP2723367B1 (fr) * | 2011-06-22 | 2017-05-03 | Indiana University Research and Technology Corporation | Co-agonistes du récepteur du glucagon et du récepteur du gpl-1 |
| JP6359972B2 (ja) * | 2011-11-03 | 2018-07-18 | ジーランド ファーマ アクティーゼルスカブ | Ｇｌｐ−１受容体アゴニストペプチドガストリンコンジュゲート |
| WO2013098408A1 (fr) * | 2011-12-30 | 2013-07-04 | Zealand Pharma A/S | Conjugués peptidiques agonistes des récepteurs de la cck et du glucagon |
| EP2797619A4 (fr) | 2011-12-30 | 2015-07-08 | Joslin Diabetes Center Inc | Compositions à base de glypican-4 et procédés destinés au traitement et au diagnostic d'une résistance à l'insuline |
| SG11201405276PA (en) * | 2012-02-27 | 2014-10-30 | Amunix Operating Inc | Xten conjugate compositions and methods of making same |
| ES2947409T3 (es) * | 2014-09-24 | 2023-08-08 | Univ Indiana Res & Tech Corp | Profármacos de insulina a base de amida lipídica |
-
2018
- 2018-06-29 EP EP18778550.6A patent/EP3645558A2/fr active Pending
- 2018-06-29 CA CA3067674A patent/CA3067674A1/fr active Pending
- 2018-06-29 SG SG11201912433YA patent/SG11201912433YA/en unknown
- 2018-06-29 CN CN201880056622.2A patent/CN111051338A/zh active Pending
- 2018-06-29 KR KR1020207002765A patent/KR102398777B1/ko active IP Right Grant
- 2018-06-29 US US16/023,901 patent/US10889627B2/en active Active
- 2018-06-29 WO PCT/IB2018/000838 patent/WO2019002945A2/fr unknown
- 2018-06-29 BR BR112019028134-7A patent/BR112019028134A2/pt unknown
- 2018-06-29 AU AU2018293467A patent/AU2018293467B2/en active Active
- 2018-06-29 JP JP2019572117A patent/JP7046990B2/ja active Active
-
2019
- 2019-12-29 IL IL271741A patent/IL271741A/en unknown
-
2020
- 2020-12-28 US US17/135,627 patent/US20210122800A1/en not_active Abandoned
-
2021
- 2021-02-04 AU AU2021200731A patent/AU2021200731B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019002945A3 (fr) | 2019-02-21 |
| AU2018293467B2 (en) | 2020-11-05 |
| JP7046990B2 (ja) | 2022-04-04 |
| US10889627B2 (en) | 2021-01-12 |
| WO2019002945A8 (fr) | 2020-02-13 |
| US20210122800A1 (en) | 2021-04-29 |
| KR20200028402A (ko) | 2020-03-16 |
| AU2021200731A1 (en) | 2021-03-04 |
| BR112019028134A2 (pt) | 2020-09-29 |
| CN111051338A (zh) | 2020-04-21 |
| AU2021200731B2 (en) | 2022-10-27 |
| AU2018293467A1 (en) | 2020-02-06 |
| US20190002519A1 (en) | 2019-01-03 |
| CA3067674A1 (fr) | 2019-01-03 |
| SG11201912433YA (en) | 2020-01-30 |
| EP3645558A2 (fr) | 2020-05-06 |
| KR102398777B1 (ko) | 2022-05-17 |
| WO2019002945A2 (fr) | 2019-01-03 |
| JP2020525478A (ja) | 2020-08-27 |
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