IL271048B - Pattern angle spatial selection structured illumination imaging - Google Patents

Pattern angle spatial selection structured illumination imaging

Info

Publication number
IL271048B
IL271048B IL271048A IL27104819A IL271048B IL 271048 B IL271048 B IL 271048B IL 271048 A IL271048 A IL 271048A IL 27104819 A IL27104819 A IL 27104819A IL 271048 B IL271048 B IL 271048B
Authority
IL
Israel
Prior art keywords
structured illumination
illumination imaging
pattern angle
spatial selection
angle spatial
Prior art date
Application number
IL271048A
Other languages
Hebrew (he)
Other versions
IL271048A (en
Inventor
Stanley S Hong
Simon Prince
Merek C Siu
Danilo Condello
Peter Clarke Newman
Shaoping Lu
Aaron Liu
Original Assignee
Illumina Inc
Stanley S Hong
Simon Prince
Merek C Siu
Danilo Condello
Peter Clarke Newman
Shaoping Lu
Aaron Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/013504 external-priority patent/WO2019143564A1/en
Application filed by Illumina Inc, Stanley S Hong, Simon Prince, Merek C Siu, Danilo Condello, Peter Clarke Newman, Shaoping Lu, Aaron Liu filed Critical Illumina Inc
Publication of IL271048A publication Critical patent/IL271048A/en
Publication of IL271048B publication Critical patent/IL271048B/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/42—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect
    • G02B27/4233—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive element [DOE] contributing to a non-imaging application
    • G02B27/425—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive element [DOE] contributing to a non-imaging application in illumination systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6478—Special lenses

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Length Measuring Devices By Optical Means (AREA)
IL271048A 2018-01-16 2019-11-28 Pattern angle spatial selection structured illumination imaging IL271048B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862618059P 2018-01-16 2018-01-16
NL2020620A NL2020620B1 (en) 2018-01-16 2018-03-20 Pattern angle spatial selection structured illumination imaging
PCT/US2019/013504 WO2019143564A1 (en) 2018-01-16 2019-01-14 Pattern angle spatial selection structured illumination imaging

Publications (2)

Publication Number Publication Date
IL271048A IL271048A (en) 2020-01-30
IL271048B true IL271048B (en) 2022-05-01

Family

ID=61868834

Family Applications (1)

Application Number Title Priority Date Filing Date
IL271048A IL271048B (en) 2018-01-16 2019-11-28 Pattern angle spatial selection structured illumination imaging

Country Status (15)

Country Link
US (1) US10996453B2 (en)
EP (1) EP3628075B1 (en)
JP (1) JP6916316B2 (en)
KR (1) KR102312777B1 (en)
CN (1) CN209979487U (en)
AU (1) AU2019209204B2 (en)
CA (1) CA3066483C (en)
IL (1) IL271048B (en)
MX (1) MX2019014173A (en)
NL (1) NL2020620B1 (en)
NZ (1) NZ759623A (en)
RU (1) RU2740206C1 (en)
SA (1) SA519410845B1 (en)
SG (1) SG11201911584YA (en)
TW (1) TWI710864B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018115001A1 (en) * 2018-06-21 2019-12-24 Carl Zeiss Microscopy Gmbh Procedure for calibrating a phase mask and microscope
TWI718557B (en) * 2018-06-29 2021-02-11 美商伊路米納有限公司 Method, system, and non-transitory computer-readable medium for predicting structured illumination parameters
US11053540B1 (en) 2020-01-17 2021-07-06 Element Biosciences, Inc. High performance fluorescence imaging module for genomic testing assay
US11716209B2 (en) * 2020-04-14 2023-08-01 The Regents Of The University Of Colorado, A Body Corporate Systems and methods for azimuthal multiplexing three-dimensional diffractive optics
CN112712585B (en) * 2020-12-15 2024-02-09 四川川大智胜软件股份有限公司 Three-dimensional imaging system and method based on arc binary coding phase shift fringe projection
JP2023006004A (en) * 2021-06-30 2023-01-18 株式会社エビデント Observation device
JP2023116048A (en) * 2022-02-09 2023-08-22 キオクシア株式会社 Measurement apparatus and measurement method
CN118226631A (en) * 2024-03-12 2024-06-21 南京理工大学 Equal wavelength periodic grating longitudinal depth structure light illumination generator for microscopic imaging

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856986A (en) 1968-12-06 1974-12-24 American Express Invest Scanned holography systems using temporal modulation
US4213706A (en) 1977-08-19 1980-07-22 The University Of Arizona Foundation Background compensating interferometer
US5761085A (en) 1996-11-12 1998-06-02 The United States Of America As Represented By The Secretary Of The Navy Method for monitoring environmental parameters at network sites
US6438272B1 (en) 1997-12-31 2002-08-20 The Research Foundation Of State University Of Ny Method and apparatus for three dimensional surface contouring using a digital video projection system
US6188478B1 (en) 1998-10-21 2001-02-13 Philips Electronics North America Corporation Method and apparatus for film-thickness measurements
US6711283B1 (en) * 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7274446B2 (en) 2001-04-07 2007-09-25 Carl Zeiss Jena Gmbh Method and arrangement for the deep resolved optical recording of a sample
JP5048899B2 (en) 2001-09-28 2012-10-17 オリンパス株式会社 microscope
US6947127B2 (en) 2001-12-10 2005-09-20 Carl Zeiss Jena Gmbh Arrangement for the optical capture of excited and/or back scattered light beam in a sample
KR100489431B1 (en) 2002-06-28 2005-05-12 학교법인연세대학교 Phase-shifting profilometry system using scanning and measuring method thereof
JP2005080181A (en) 2003-09-03 2005-03-24 Nikon Corp Image reading apparatus and image reading program
US7532323B2 (en) 2003-10-28 2009-05-12 Cha-Min Tang Spatial light modulator apparatus and method
US20050221351A1 (en) 2004-04-06 2005-10-06 Affymetrix, Inc. Methods and devices for microarray image analysis
JP4899408B2 (en) * 2005-02-25 2012-03-21 株式会社ニコン Microscope equipment
CN1292227C (en) 2005-07-12 2006-12-27 中国科学院上海光学精密机械研究所 Calibration method for spatial resolution of high-resolution digital interferometer
WO2007061632A2 (en) 2005-11-09 2007-05-31 Geometric Informatics, Inc. Method and apparatus for absolute-coordinate three-dimensional surface imaging
JP2007199572A (en) * 2006-01-30 2007-08-09 Nikon Corp Microscope
US7803609B2 (en) 2006-07-21 2010-09-28 Affymetrix, Inc. System, method, and product for generating patterned illumination
DE102006044229B4 (en) 2006-09-20 2023-09-28 Carl Zeiss Microscopy Gmbh Method and device for image processing with higher harmonics of a lighting grid
DE102006047912A1 (en) 2006-10-06 2008-04-10 Carl Zeiss Microimaging Gmbh Method and device for parallelized microscopic imaging
JP5136422B2 (en) 2006-12-12 2013-02-06 株式会社ニコン Microscope device and image processing method
US8848199B2 (en) 2007-07-10 2014-09-30 Massachusetts Institute Of Technology Tomographic phase microscopy
US8759077B2 (en) 2007-08-28 2014-06-24 Lightspeed Genomics, Inc. Apparatus for selective excitation of microparticles
US8222040B2 (en) 2007-08-28 2012-07-17 Lightspeed Genomics, Inc. Nucleic acid sequencing by selective excitation of microparticles
WO2009031418A1 (en) * 2007-09-05 2009-03-12 Nikon Corporation Microscope device
US8509879B2 (en) 2007-11-06 2013-08-13 The Regents Of The University Of California Apparatus and method for widefield functional imaging (WiFI) using integrated structured illumination and laser speckle imaging
US8537461B2 (en) 2007-11-26 2013-09-17 Carl Zeiss Microimaging Gmbh Method and configuration for the optical detection of an illuminated specimen
US20090219607A1 (en) 2008-01-17 2009-09-03 Baylor College Of Medicine Method and apparatus for enhanced resolution microscopy of living biological nanostructures
EP2235584B1 (en) * 2008-01-21 2020-09-16 Apple Inc. Optical designs for zero order reduction
DE102008009216A1 (en) 2008-02-13 2009-08-20 Carl Zeiss Microimaging Gmbh Apparatus and method for spatially high resolution imaging of a structure of a sample
US8773635B2 (en) * 2008-12-19 2014-07-08 Nikon Corporation Exposure apparatus, exposure method, and device manufacturing method
TWI426296B (en) * 2009-06-19 2014-02-11 Ind Tech Res Inst Method and system for three-dimensional polarization-based confocal microscopy
KR101817110B1 (en) 2009-10-08 2018-02-21 유니베르시테 리브레 드 브룩크젤즈 Off-axis interferometer
KR101117501B1 (en) 2010-02-12 2012-03-07 한국과학기술원 Structured illumination confocal microscope with the use of cross-type linear structured illumination
US8502867B2 (en) 2010-03-19 2013-08-06 Lightspeed Genomics, Inc. Synthetic aperture optics imaging method using minimum selective excitation patterns
US9465228B2 (en) 2010-03-19 2016-10-11 Optical Biosystems, Inc. Illumination apparatus optimized for synthetic aperture optics imaging using minimum selective excitation patterns
JP5412394B2 (en) * 2010-09-30 2014-02-12 オリンパス株式会社 Sample observation equipment
JP5661194B2 (en) 2010-11-12 2015-01-28 エーエスエムエル ネザーランズ ビー．ブイ． Metrology method and apparatus, lithography system and device manufacturing method
US8796185B2 (en) 2011-03-08 2014-08-05 Lightspeed Genomics, Inc. Self-assembling high density ordered patterned biomolecule array and method for making and using the same
US8817362B2 (en) 2011-04-29 2014-08-26 Lightspeed Genomics, Inc. Modular pattern illumination and light beam multiplexing for selective excitation of microparticles
EP2718465B1 (en) 2011-06-09 2022-04-13 Illumina, Inc. Method of making an analyte array
EP2737453B1 (en) * 2011-07-13 2019-12-18 Leica Biosystems Imaging, Inc. Standardizing fluorescence microscopy systems
EP2802861A4 (en) * 2012-01-11 2015-08-19 Hughes Howard Med Inst Multi-dimensional imaging using multi-focus microscopy
EP2806262A4 (en) * 2012-01-18 2015-09-23 Nikon Corp Structured illumination device, structured illumination microscope device, and structured illumination method
TWI467227B (en) * 2012-04-12 2015-01-01 Univ Nat Formosa Three-dimensional microscope device and method using the same
JP5888416B2 (en) * 2012-07-19 2016-03-22 株式会社ニコン Structured illumination microscope
US10378053B2 (en) 2017-03-17 2019-08-13 Apton Biosystems, Inc. Sequencing and high resolution imaging
EP2801854B1 (en) * 2013-05-10 2017-07-19 Ruprecht-Karls-Universität Heidelberg Method and apparatus for combination of localization microscopy and structured illumination microscopy
KR101541610B1 (en) * 2013-12-09 2015-08-03 한양대학교 산학협력단 Structural illumination microscopy based on spatial filter
WO2016125281A1 (en) 2015-02-05 2016-08-11 株式会社ニコン Structured illumination microscope, observation method, and control program
WO2016149397A1 (en) 2015-03-16 2016-09-22 Pacific Biosciences Of California, Inc. Integrated devices and systems for free-space optical coupling
CN104793329B (en) * 2015-04-15 2017-06-06 黑龙江大学 A kind of device and method of femtosecond laser rotation manipulation optical tweezer
DE102016007839A1 (en) * 2016-06-28 2017-12-28 Horst Wochnowski High-resolution method for microscopy and nanostructuring of substrate surfaces based on the SIM method (Structured Illumination Microscopy)

Also Published As

Publication number Publication date
RU2740206C1 (en) 2021-01-12
KR102312777B1 (en) 2021-10-14
IL271048A (en) 2020-01-30
US10996453B2 (en) 2021-05-04
TW201932991A (en) 2019-08-16
MX2019014173A (en) 2021-02-09
EP3628075A4 (en) 2020-07-15
EP3628075A1 (en) 2020-04-01
NZ759623A (en) 2022-05-27
KR20200019148A (en) 2020-02-21
EP3628075B1 (en) 2023-01-25
NL2020620B1 (en) 2019-07-25
SG11201911584YA (en) 2020-01-30
SA519410845B1 (en) 2022-06-16
CN209979487U (en) 2020-01-21
CA3066483C (en) 2022-06-28
AU2019209204B2 (en) 2021-06-17
BR112019028316A2 (en) 2020-07-14
CA3066483A1 (en) 2019-07-25
US20200218050A1 (en) 2020-07-09
AU2019209204A1 (en) 2020-11-26
JP2020532758A (en) 2020-11-12
TWI710864B (en) 2020-11-21
JP6916316B2 (en) 2021-08-11

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