IL270974A - Methods of determining therapies based on single cell characterization of circulating tumor cells (ctcs) in metastatic disease - Google Patents
Methods of determining therapies based on single cell characterization of circulating tumor cells (ctcs) in metastatic diseaseInfo
- Publication number
- IL270974A IL270974A IL270974A IL27097419A IL270974A IL 270974 A IL270974 A IL 270974A IL 270974 A IL270974 A IL 270974A IL 27097419 A IL27097419 A IL 27097419A IL 270974 A IL270974 A IL 270974A
- Authority
- IL
- Israel
- Prior art keywords
- ctc
- methods
- cancer cells
- single cell
- metastatic disease
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762514642P | 2017-06-02 | 2017-06-02 | |
| US201762531725P | 2017-07-12 | 2017-07-12 | |
| PCT/US2018/035581 WO2018222979A1 (en) | 2017-06-02 | 2018-06-01 | Methods of determining therapies based on single cell characterization of circulating tumor cells (ctcs) in metastatic disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL270974A true IL270974A (en) | 2020-01-30 |
Family
ID=64455086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL270974A IL270974A (en) | 2017-06-02 | 2019-11-27 | Methods of determining therapies based on single cell characterization of circulating tumor cells (ctcs) in metastatic disease |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20220260574A1 (enExample) |
| EP (1) | EP3631445B1 (enExample) |
| JP (2) | JP2020522697A (enExample) |
| CN (1) | CN110998318A (enExample) |
| AU (1) | AU2018275265A1 (enExample) |
| CA (1) | CA3065316A1 (enExample) |
| IL (1) | IL270974A (enExample) |
| WO (1) | WO2018222979A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3966782A2 (en) * | 2019-05-06 | 2022-03-16 | Tesaro, Inc. | Methods for characterizing and treating a cancer type using cancer images |
| EP4641584A3 (en) * | 2019-05-14 | 2025-12-10 | University of Pittsburgh - of the Commonwealth System of Higher Education | System and method for characterizing cellular phenotypic diversity from multi-parameter cellular and sub-cellular imaging data |
| US12207939B2 (en) | 2019-11-27 | 2025-01-28 | University Of Cincinnati | Assessing treatment response with estimated number of tumor cells |
| JP7764039B2 (ja) * | 2020-01-17 | 2025-11-05 | ウニヴェルズィテート チューリッヒ | 腫瘍サンプルの単一細胞病理解析 |
| CN114092934A (zh) * | 2020-07-31 | 2022-02-25 | 骏实生物科技(上海)有限公司 | 循环肿瘤细胞的分类方法 |
| CN114594252A (zh) * | 2020-12-03 | 2022-06-07 | 复旦大学附属中山医院 | 循环肿瘤细胞形态学特征在胃癌临床诊疗中的应用 |
| JP7836038B2 (ja) * | 2020-12-10 | 2026-03-26 | 国立大学法人信州大学 | メラノーマ患者の治療効果を判定する方法 |
| US20240054640A1 (en) * | 2020-12-15 | 2024-02-15 | Carnegie Mellon University | System, Method, and Computer Program Product for Classification of Diseases Based on Expansion Microscopic Images |
| JP7824031B2 (ja) * | 2021-03-12 | 2026-03-04 | シスメックス株式会社 | 分析方法および分析装置 |
| EP4060320A1 (en) | 2021-03-12 | 2022-09-21 | Sysmex Corporation | Analysis method and analyzer |
| US11735303B2 (en) * | 2021-06-22 | 2023-08-22 | David Haase | Apparatus and method for determining a composition of a replacement therapy treatment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3033088A4 (en) * | 2013-08-12 | 2017-03-08 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
| CN106062561B (zh) * | 2013-09-30 | 2021-11-09 | 斯克利普斯研究院 | 为了监测前列腺癌患者中的肿瘤进化进行循环肿瘤细胞的基因型和表型分析 |
| WO2015112955A1 (en) * | 2014-01-27 | 2015-07-30 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for prostate cancer biomarkers |
| EP3100052B1 (en) * | 2014-01-30 | 2021-03-10 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for biomarkers predictive of resistance to androgen receptor (ar) targeted therapies |
| EP3186393A4 (en) * | 2014-08-25 | 2018-01-10 | The Johns Hopkins University | Methods and compositions related to prostate cancer therapeutics |
| US20180155794A1 (en) * | 2015-05-29 | 2018-06-07 | Epic Sciences, Inc. | Intra-patient genomic heterogeneity of single circulating tumor cells (ctcs) associated to phenotypic ctc heterogeneity in metastatic castrate resistant prostate cancer (mcrpc) |
-
2018
- 2018-06-01 CN CN201880050607.7A patent/CN110998318A/zh active Pending
- 2018-06-01 WO PCT/US2018/035581 patent/WO2018222979A1/en not_active Ceased
- 2018-06-01 US US16/617,423 patent/US20220260574A1/en not_active Abandoned
- 2018-06-01 EP EP18810303.0A patent/EP3631445B1/en active Active
- 2018-06-01 AU AU2018275265A patent/AU2018275265A1/en not_active Abandoned
- 2018-06-01 CA CA3065316A patent/CA3065316A1/en active Pending
- 2018-06-01 JP JP2019566358A patent/JP2020522697A/ja active Pending
-
2019
- 2019-11-27 IL IL270974A patent/IL270974A/en unknown
-
2023
- 2023-05-26 JP JP2023086656A patent/JP2023120213A/ja active Pending
-
2024
- 2024-06-18 US US18/746,816 patent/US20250155440A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018222979A1 (en) | 2018-12-06 |
| CA3065316A1 (en) | 2018-12-06 |
| JP2020522697A (ja) | 2020-07-30 |
| JP2023120213A (ja) | 2023-08-29 |
| EP3631445B1 (en) | 2024-09-25 |
| US20220260574A1 (en) | 2022-08-18 |
| AU2018275265A1 (en) | 2020-01-30 |
| EP3631445A4 (en) | 2021-05-26 |
| US20250155440A1 (en) | 2025-05-15 |
| EP3631445A1 (en) | 2020-04-08 |
| CN110998318A (zh) | 2020-04-10 |
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