IL267708A - Oxalate salts of tianeptine and polymorphs thereof, preparations containing them and their uses - Google Patents
Oxalate salts of tianeptine and polymorphs thereof, preparations containing them and their usesInfo
- Publication number
- IL267708A IL267708A IL267708A IL26770819A IL267708A IL 267708 A IL267708 A IL 267708A IL 267708 A IL267708 A IL 267708A IL 26770819 A IL26770819 A IL 26770819A IL 267708 A IL267708 A IL 267708A
- Authority
- IL
- Israel
- Prior art keywords
- polymorphs
- compositions
- same
- oxalate salts
- tianeptine oxalate
- Prior art date
Links
- -1 Tianeptine oxalate salts Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960005138 tianeptine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662439533P | 2016-12-28 | 2016-12-28 | |
| PCT/IB2017/001709 WO2018122606A1 (en) | 2016-12-28 | 2017-12-28 | Tianeptine oxalate salts and polymorphs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL267708A true IL267708A (en) | 2019-08-29 |
Family
ID=61283255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL267708A IL267708A (en) | 2016-12-28 | 2019-06-27 | Oxalate salts of tianeptine and polymorphs thereof, preparations containing them and their uses |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10449203B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3562812A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2020503330A (cg-RX-API-DMAC7.html) |
| CN (1) | CN110418785A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017385958B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019013244A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3048324A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL267708A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2019007891A (cg-RX-API-DMAC7.html) |
| MY (1) | MY199385A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ754797A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018122606A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201904185B (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY199385A (en) * | 2016-12-28 | 2023-10-25 | Tonix Pharma Holdings Ltd | Tianeptine oxalate salts and polymorphs |
| WO2022197719A1 (en) | 2021-03-15 | 2022-09-22 | Tonix Pharmaceuticals Holding Corp. | Tianeptine oxalate and naloxone combination for the treatment of major depressive disorder |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3758528A (en) * | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
| FR2635461B1 (fr) * | 1988-08-18 | 1992-01-17 | Adir | Utilisation de derives tricycliques pour l'obtention de medicaments destines au traitement du stress |
| US5405842A (en) | 1994-01-28 | 1995-04-11 | Silverman; Bernard A. | Treatment of steroid dependent asthmatics |
| FR2791891A1 (fr) | 1999-04-07 | 2000-10-13 | Adir | Utilisation de la tianeptine pour l'obtention de medicaments destines au traitement des pathologies de la neurodegenerescence |
| FR2810979B1 (fr) * | 2000-06-29 | 2002-08-23 | Adir | Nouveaux derives de diphenyluree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| US9314469B2 (en) | 2008-05-05 | 2016-04-19 | Tonix Pharma Holdings Limited | Method for treating neurocognitive dysfunction |
| US8198268B2 (en) * | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| MY199385A (en) * | 2016-12-28 | 2023-10-25 | Tonix Pharma Holdings Ltd | Tianeptine oxalate salts and polymorphs |
-
2017
- 2017-12-28 MY MYPI2019003711A patent/MY199385A/en unknown
- 2017-12-28 US US15/856,818 patent/US10449203B2/en active Active
- 2017-12-28 WO PCT/IB2017/001709 patent/WO2018122606A1/en not_active Ceased
- 2017-12-28 BR BR112019013244A patent/BR112019013244A2/pt not_active IP Right Cessation
- 2017-12-28 JP JP2019535330A patent/JP2020503330A/ja active Pending
- 2017-12-28 CA CA3048324A patent/CA3048324A1/en active Pending
- 2017-12-28 EP EP17844642.3A patent/EP3562812A1/en not_active Withdrawn
- 2017-12-28 MX MX2019007891A patent/MX2019007891A/es unknown
- 2017-12-28 CN CN201780085697.9A patent/CN110418785A/zh active Pending
- 2017-12-28 NZ NZ754797A patent/NZ754797A/en not_active IP Right Cessation
- 2017-12-28 AU AU2017385958A patent/AU2017385958B2/en not_active Ceased
-
2019
- 2019-06-26 ZA ZA2019/04185A patent/ZA201904185B/en unknown
- 2019-06-27 IL IL267708A patent/IL267708A/en unknown
- 2019-10-09 US US16/597,065 patent/US10946027B2/en active Active
-
2022
- 2022-11-10 JP JP2022180549A patent/JP2023001340A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017385958A1 (en) | 2019-07-11 |
| MX2019007891A (es) | 2019-12-16 |
| US20180338984A1 (en) | 2018-11-29 |
| BR112019013244A2 (pt) | 2019-12-24 |
| EP3562812A1 (en) | 2019-11-06 |
| CA3048324A1 (en) | 2018-07-05 |
| US20200276208A1 (en) | 2020-09-03 |
| JP2023001340A (ja) | 2023-01-04 |
| NZ754797A (en) | 2022-05-27 |
| US10449203B2 (en) | 2019-10-22 |
| MY199385A (en) | 2023-10-25 |
| ZA201904185B (en) | 2021-10-27 |
| AU2017385958B2 (en) | 2021-12-02 |
| WO2018122606A1 (en) | 2018-07-05 |
| CN110418785A (zh) | 2019-11-05 |
| JP2020503330A (ja) | 2020-01-30 |
| US10946027B2 (en) | 2021-03-16 |
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