IL26729A - 2-mercaptoimidazole derivatives and process for their preparation - Google Patents
2-mercaptoimidazole derivatives and process for their preparationInfo
- Publication number
- IL26729A IL26729A IL26729A IL2672966A IL26729A IL 26729 A IL26729 A IL 26729A IL 26729 A IL26729 A IL 26729A IL 2672966 A IL2672966 A IL 2672966A IL 26729 A IL26729 A IL 26729A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- mercaptoimidazole derivatives
- mercaptoimidazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
- C07C331/16—Isothiocyanates
- C07C331/18—Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms
- C07C331/20—Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50024565A | 1965-10-21 | 1965-10-21 | |
US72192868A | 1968-04-17 | 1968-04-17 | |
US72193068A | 1968-04-17 | 1968-04-17 | |
US72192968A | 1968-04-17 | 1968-04-17 | |
US87494769A | 1969-11-07 | 1969-11-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL26729A true IL26729A (en) | 1970-10-30 |
Family
ID=27541791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL26729A IL26729A (en) | 1965-10-21 | 1966-10-20 | 2-mercaptoimidazole derivatives and process for their preparation |
Country Status (10)
Country | Link |
---|---|
US (4) | US3488423A (zh) |
BE (1) | BE688585A (zh) |
BR (1) | BR6683847D0 (zh) |
DE (1) | DE1695093A1 (zh) |
FR (2) | FR1509975A (zh) |
GB (1) | GB1155580A (zh) |
IL (1) | IL26729A (zh) |
NL (3) | NL6614808A (zh) |
NO (1) | NO120426B (zh) |
SE (1) | SE345453B (zh) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
US4190666A (en) * | 1975-08-11 | 1980-02-26 | E. I. Du Pont De Nemours And Company | Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones |
US4159338A (en) * | 1977-02-09 | 1979-06-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
US4182769A (en) * | 1977-02-09 | 1980-01-08 | E. I. Du Pont De Nemours And Company | Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones |
DE2823197A1 (de) * | 1978-05-24 | 1979-11-29 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
US4215135A (en) * | 1979-06-08 | 1980-07-29 | E. I. Du Pont De Nemours And Company | Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles |
US4232029A (en) * | 1978-11-03 | 1980-11-04 | American Home Products Corporation | 1-Hydroxyimidazole-5-methanamine derivatives |
DE2856909A1 (de) * | 1978-12-28 | 1980-07-17 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3025484A1 (de) * | 1980-07-03 | 1982-02-04 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
US4338453A (en) * | 1980-09-17 | 1982-07-06 | The Upjohn Company | Aminoalkyl-1,2,4-triazoles |
US4372964A (en) * | 1980-10-30 | 1983-02-08 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols |
US4330552A (en) * | 1980-11-06 | 1982-05-18 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-arylthioimidazoles |
US4482775A (en) * | 1982-09-22 | 1984-11-13 | Chemical Research & Licensing Company | Isomerization of C4 alkenes |
US4532331A (en) * | 1983-04-12 | 1985-07-30 | Smithkline Beckman Corporation | 1-Benzyl-2-aminomethyl imidazole derivatives |
US4992459A (en) * | 1983-04-12 | 1991-02-12 | Smithkline Beecham Corporation | Dopamine-β-hydroxylase inhibitors |
PT78388B (en) * | 1983-04-12 | 1986-09-15 | Smithkline Beckman Corp | Dopamine-beta-hydroxylase inhibitors |
US4772723A (en) * | 1983-04-12 | 1988-09-20 | Smithkline Beckman Corporation | Dopamine β-hydroxylase inhibitors |
US4863944A (en) * | 1983-04-12 | 1989-09-05 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4532250A (en) * | 1983-11-23 | 1985-07-30 | American Hospital Supply Corporation | 5-Heteroarylimidazol-2-ones having cardiotonic activity |
JPS61110266A (ja) * | 1984-11-05 | 1986-05-28 | Omron Tateisi Electronics Co | カード発行方法 |
DE3508665A1 (de) * | 1985-03-12 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Heterocyclische sulfide und ihre anwendung als immunmodulatoren |
US4634711A (en) * | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
US4719223A (en) * | 1985-10-31 | 1988-01-12 | Smithkline Beckman Corporation | Imidazolethiol dopamine-beta-hydroxylase inhibitors |
US4743613A (en) * | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity |
JP2581556B2 (ja) * | 1986-05-06 | 1997-02-12 | メレルダウファーマスーティカルズ インコーポレーテッド | 新規なドパミンベ−タヒドロキシラ−ゼ抑制剤 |
US5057613A (en) * | 1986-05-06 | 1991-10-15 | Merrell Dow Pharmaceuticals | Novel thione dopamine beta hydroxylase inhibitors |
US4935438A (en) * | 1987-12-29 | 1990-06-19 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4882348A (en) * | 1987-12-29 | 1989-11-21 | Smithkline Beckman Corporation | 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors |
US4876266A (en) * | 1987-12-31 | 1989-10-24 | Smithkline Beckman Corporation | 1-aralkyl-2-mercaptoimidazolines as DBH inhibitors |
WO1989006131A1 (en) * | 1987-12-31 | 1989-07-13 | Smithkline Beckman Corporation | 1-aralkyl-1,2-dihydropyrimidine-2-thiones |
US5300519A (en) * | 1988-07-06 | 1994-04-05 | The University Of Sheffield | Immunosuppressive agents |
US5359139A (en) * | 1991-03-18 | 1994-10-25 | Albemarle Corporation | Tertiary amine treatment |
US5393913A (en) * | 1993-03-03 | 1995-02-28 | Rhone-Poulenc Inc. | N-formylanilines |
US6365616B1 (en) * | 1998-08-31 | 2002-04-02 | Sentron Medical, Inc. | Methimazole derivatives and tautomeric cyclic thiones to treat autoimmune diseases |
EP1112072A2 (en) * | 1998-08-31 | 2001-07-04 | Sentron Medical, Inc. | Methimazole derivatives and tautomeric cyclic thiones to treat autoimmune diseases |
US20020142974A1 (en) * | 1998-09-11 | 2002-10-03 | Leonard D. Kohn | Immune activation by double-stranded polynucleotides |
DE10107683A1 (de) * | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
FR2831822A1 (fr) * | 2001-11-07 | 2003-05-09 | Inst Nat Sante Rech Med | Utilisation therapeutique de derives 4-mercapto- ou 4-seleno-imidazoles |
AU2005271162A1 (en) * | 2004-08-11 | 2006-02-16 | Janssen Pharmaceutica N.V. | Mercaptoimidazoles as CCR2 receptor antagonists |
CN106659714B (zh) | 2014-07-18 | 2021-06-08 | 俄亥俄大学 | 用于改变生物信号传导的咪唑和噻唑组合物 |
DE102022119618B3 (de) | 2022-08-04 | 2023-12-28 | Hans Schröder, Maschinenbau, Gesellschaft mit beschränkter Haftung | Schwenkbiegemaschine zur Erzeugung eines Hohlumschlags an einem Blech und Blechbiegeverfahren |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2585388A (en) * | 1948-11-17 | 1952-02-12 | Lilly Co Eli | Preparation of 2-mercaptoimidazoles |
-
1966
- 1966-10-20 DE DE19661695093 patent/DE1695093A1/de active Pending
- 1966-10-20 NL NL6614808A patent/NL6614808A/xx unknown
- 1966-10-20 BE BE688585D patent/BE688585A/xx unknown
- 1966-10-20 GB GB46982/66A patent/GB1155580A/en not_active Expired
- 1966-10-20 FR FR80818A patent/FR1509975A/fr not_active Expired
- 1966-10-20 NO NO165248A patent/NO120426B/no unknown
- 1966-10-20 SE SE14303/66A patent/SE345453B/xx unknown
- 1966-10-20 IL IL26729A patent/IL26729A/xx unknown
- 1966-10-30 BR BR183847/66A patent/BR6683847D0/pt unknown
-
1967
- 1967-01-19 FR FR91767A patent/FR6115M/fr not_active Expired
-
1968
- 1968-04-17 US US721928A patent/US3488423A/en not_active Expired - Lifetime
- 1968-04-17 US US721929A patent/US3622584A/en not_active Expired - Lifetime
- 1968-04-17 US US721930A patent/US3505350A/en not_active Expired - Lifetime
-
1969
- 1969-11-07 US US874947A patent/US3629473A/en not_active Expired - Lifetime
-
1971
- 1971-09-03 NL NL7112161A patent/NL7112161A/xx unknown
- 1971-09-03 NL NL7112160A patent/NL7112160A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
GB1155580A (en) | 1969-06-18 |
NL6614808A (zh) | 1967-04-24 |
US3505350A (en) | 1970-04-07 |
NO120426B (zh) | 1970-10-19 |
FR6115M (zh) | 1968-06-17 |
SE345453B (zh) | 1972-05-29 |
BE688585A (zh) | 1967-04-20 |
NL7112161A (zh) | 1971-12-27 |
US3488423A (en) | 1970-01-06 |
DE1695093A1 (de) | 1970-12-10 |
NL7112160A (zh) | 1971-12-27 |
US3629473A (en) | 1971-12-21 |
BR6683847D0 (pt) | 1973-12-04 |
US3622584A (en) | 1971-11-23 |
FR1509975A (fr) | 1968-01-19 |
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