IL265902B2 - Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseases - Google Patents
Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseasesInfo
- Publication number
- IL265902B2 IL265902B2 IL265902A IL26590219A IL265902B2 IL 265902 B2 IL265902 B2 IL 265902B2 IL 265902 A IL265902 A IL 265902A IL 26590219 A IL26590219 A IL 26590219A IL 265902 B2 IL265902 B2 IL 265902B2
- Authority
- IL
- Israel
- Prior art keywords
- active ingredient
- pharmaceutical composition
- cannabinoid
- use according
- cannabinoids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3482—Cannabis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662406764P | 2016-10-11 | 2016-10-11 | |
| PCT/US2017/055989 WO2018071452A1 (en) | 2016-10-11 | 2017-10-10 | Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL265902A IL265902A (en) | 2019-06-30 |
| IL265902B1 IL265902B1 (en) | 2023-12-01 |
| IL265902B2 true IL265902B2 (en) | 2024-04-01 |
Family
ID=60382587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL265902A IL265902B2 (en) | 2016-10-11 | 2017-10-10 | Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseases |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10653640B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3525823B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7225103B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN115887440A (cg-RX-API-DMAC7.html) |
| AU (3) | AU2017344040A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3039413A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL265902B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018071452A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| WO2018205022A1 (en) | 2017-05-08 | 2018-11-15 | Inmed Pharmaceuticals Inc. | Ocular drug delivery formulation |
| WO2018217803A2 (en) | 2017-05-22 | 2018-11-29 | Growblox Life Sciences L.L.C. | Myrcene-containing complex mixtures targeting trpv1 |
| EP3745884A1 (en) | 2018-01-31 | 2020-12-09 | Canopy Holdings, Llc | Hemp powder |
| EP3796903A1 (en) | 2018-05-22 | 2021-03-31 | GBS Global Biopharma, Inc. | Cannabinoids and/or terpenes for use in trpv1 modulation |
| US11040932B2 (en) | 2018-10-10 | 2021-06-22 | Treehouse Biotech, Inc. | Synthesis of cannabigerol |
| EP3902538A4 (en) * | 2018-12-29 | 2023-01-18 | Buzzelet Development And Technologies Ltd | ISOLATED OR SYNTHETIC CANNABINOID COMPOSITIONS WITH SELECTED TERPEN BLEND AND METHODS OF USE THEREOF |
| SG11202111809XA (en) * | 2019-04-24 | 2021-11-29 | Inmed Pharmaceuticals Inc | Compositions and methods for use of cannabinoids for neuroprotection |
| CA3144983A1 (en) * | 2019-06-28 | 2020-12-30 | Gbs Global Biopharma, Inc. | Treatment of pain using allosteric modulator of trpv1 |
| US20220241239A1 (en) * | 2019-07-17 | 2022-08-04 | Zealand Pharma A/S | Pharmaceutical composition for subcutaneous administration |
| US12409131B2 (en) | 2019-10-03 | 2025-09-09 | Pike Therapeutics Usa, Inc. | Transdermal delivery of dronabinol |
| US20210100737A1 (en) | 2019-10-03 | 2021-04-08 | Starton Therapeutics, Inc. | Transdermal delivery of dronabinol |
| CN113694049B (zh) * | 2020-05-21 | 2022-11-22 | 汉义生物科技(北京)有限公司 | 大麻素类化合物及其在治疗帕金森症中的应用 |
| MX2023000314A (es) * | 2020-08-17 | 2023-02-22 | Pike Therapeutics Inc | Formulaciones farmaceuticas transdermicas de cannabinoides. |
| WO2022040367A2 (en) * | 2020-08-18 | 2022-02-24 | Gbs Global Biopharma, Inc. | Cannabinoid-containing complex mixtures for the treatment of cytokine release syndrome while preserving key anti-viral immune reactions |
| EP4124336B1 (en) | 2021-07-30 | 2023-10-25 | Cannamedical Pharma GmbH | Transmucosal patch comprising a cannabinoid and/or an opioid |
| CN113368086B (zh) * | 2021-08-11 | 2021-12-03 | 龙麻(上海)医药研发有限责任公司 | 一种大麻素组合物及其在制备治疗帕金森、阿尔茨海默等神经退行性疾病的药物中的应用 |
| US20230263766A1 (en) * | 2021-09-28 | 2023-08-24 | Gbs Global Biopharma, Inc. | Cannabinoid-containing formulations for parkinsonian movement disorders |
| WO2024148117A2 (en) * | 2023-01-04 | 2024-07-11 | Florascience Inc. | Methods of treating neurodegenerative diseases or conditions |
| WO2024160792A1 (en) | 2023-01-30 | 2024-08-08 | Cannamedical Pharma Gmbh | Improved transmucosal patch comprising a cannabinoid and/or an opioid |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110257256A1 (en) * | 2008-07-31 | 2011-10-20 | Bionoria Research Gmbh | Cannabinoids for use in treating or preventing cognitive impairment and dementia |
| GB2492487A (en) * | 2011-07-01 | 2013-01-02 | Gw Pharma Ltd | Cannabichromene (CBC), cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA) for the treatment of neurodegenerative diseases |
| WO2014145490A2 (en) * | 2013-03-15 | 2014-09-18 | Biotech Institute, Llc | Breeding, production, processing and use of specialty cannabis |
| WO2014200350A1 (en) * | 2013-06-13 | 2014-12-18 | Cannabis Science International Holding B.V. | Composition for the treatment of neurobehavioral disorders |
| US20160250270A1 (en) * | 2015-02-27 | 2016-09-01 | Ebbu, LLC | Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8207733A (pt) | 1981-06-04 | 1983-05-10 | Pharmasol Corp | Recipiente pressurizado com bomba de suprimento |
| US4778810A (en) | 1987-01-08 | 1988-10-18 | Nastech Pharmaceutical Co., Inc. | Nasal delivery of caffeine |
| US7052678B2 (en) | 1997-09-15 | 2006-05-30 | Massachusetts Institute Of Technology | Particles for inhalation having sustained release properties |
| JP2002510603A (ja) | 1998-04-08 | 2002-04-09 | イーライ・リリー・アンド・カンパニー | ラロキシフェンの肺および鼻腔デリバリー |
| US6403126B1 (en) | 1999-05-26 | 2002-06-11 | Websar Innovations Inc. | Cannabinoid extraction method |
| DE10051427C1 (de) | 2000-10-17 | 2002-06-13 | Adam Mueller | Verfahren zur Herstellung eines Tetrahydrocannabinol- und Cannabidiol-haltigen Extraktes aus Cannabis-Pflanzenmaterial sowie Cannabis-Extrakte |
| CA2533400C (en) * | 2001-02-14 | 2017-01-03 | Gw Pharma Limited | Cannabinoids pharmaceutical formulations |
| GB2391865B (en) * | 2002-08-14 | 2005-06-01 | Gw Pharma Ltd | Improvements in the extraction of pharmaceutically active components from plant materials |
| US20060241130A1 (en) * | 2003-01-31 | 2006-10-26 | Ehud Keinan | Anti-inflammatory compositions and uses thereof |
| GB2434312B (en) | 2006-01-18 | 2011-06-29 | Gw Pharma Ltd | Cannabinoid-containing plant extracts as neuroprotective agents |
| GB2448535A (en) * | 2007-04-19 | 2008-10-22 | Gw Pharma Ltd | New use for cannabinoid-containing plant extracts |
| US8277781B2 (en) | 2009-03-13 | 2012-10-02 | Luitpold Pharmaceuticals, Inc. | Device for intranasal administration |
| MX2011011514A (es) | 2009-04-28 | 2011-11-18 | Alltranz Inc | Formulaciones de canabidiol y metodos para utilizarlas. |
| US9066910B2 (en) | 2010-04-15 | 2015-06-30 | Steven Rosenblatt | Methods and compositions of cannabis extracts |
| GB2491118B (en) * | 2011-05-20 | 2015-12-30 | Otsuka Pharma Co Ltd | Cannabinoids for use in the treatment of neuropathic pain |
| GB2514054A (en) | 2011-09-29 | 2014-11-12 | Gw Pharma Ltd | A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD) |
| US20160108004A1 (en) * | 2013-05-24 | 2016-04-21 | Nestec S.A. | Treatment or prevention of neurodegenerative disorders using menthol, linalool and/or icilin |
| US20150057342A1 (en) | 2013-08-21 | 2015-02-26 | Cannabics Pharmaceuticals Inc | Compositions for combined immediate and sustained release of cannabinoids, methods of manufacture and use thereof |
| CN114191420A (zh) | 2014-05-29 | 2022-03-18 | 雷迪厄斯制药公司 | 稳定的大麻素类化合物制剂 |
| GB2527599A (en) | 2014-06-27 | 2015-12-30 | Gw Pharma Ltd | Use of 7-OH-Cannabidiol (7-OH-CBD) and/or 7-OH-Cannabidivarin (7-OH-CBDV) in the treatment of epilepsy |
| GB2527590A (en) | 2014-06-27 | 2015-12-30 | Otsuka Pharma Co Ltd | Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer |
| DK3258942T3 (da) | 2015-02-16 | 2021-01-25 | Apirx Pharmaceutical Usa Llc | Kosmetiske og topiske sammensætninger omfattende cannabigerol og cannabidiol |
| WO2017193072A1 (en) * | 2016-05-06 | 2017-11-09 | Harvest Direct Enterprises Llc | The manufacturing methods, compositions, and medical applications of orally administered cannabis pharmaceuticals |
-
2017
- 2017-10-10 CA CA3039413A patent/CA3039413A1/en active Pending
- 2017-10-10 CN CN202310039015.8A patent/CN115887440A/zh active Pending
- 2017-10-10 US US15/729,565 patent/US10653640B2/en active Active
- 2017-10-10 JP JP2019540310A patent/JP7225103B2/ja active Active
- 2017-10-10 EP EP17800639.1A patent/EP3525823B1/en active Active
- 2017-10-10 WO PCT/US2017/055989 patent/WO2018071452A1/en not_active Ceased
- 2017-10-10 AU AU2017344040A patent/AU2017344040A1/en not_active Abandoned
- 2017-10-10 IL IL265902A patent/IL265902B2/en unknown
- 2017-10-10 CN CN201780071100.5A patent/CN109963595B/zh active Active
-
2020
- 2020-04-09 US US16/844,713 patent/US11980592B2/en active Active
-
2023
- 2023-02-08 JP JP2023017412A patent/JP2023058599A/ja active Pending
- 2023-08-30 AU AU2023222872A patent/AU2023222872A1/en not_active Abandoned
-
2024
- 2024-05-13 US US18/663,034 patent/US20250108016A1/en active Pending
-
2025
- 2025-08-11 AU AU2025213702A patent/AU2025213702A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110257256A1 (en) * | 2008-07-31 | 2011-10-20 | Bionoria Research Gmbh | Cannabinoids for use in treating or preventing cognitive impairment and dementia |
| GB2492487A (en) * | 2011-07-01 | 2013-01-02 | Gw Pharma Ltd | Cannabichromene (CBC), cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA) for the treatment of neurodegenerative diseases |
| WO2014145490A2 (en) * | 2013-03-15 | 2014-09-18 | Biotech Institute, Llc | Breeding, production, processing and use of specialty cannabis |
| WO2014200350A1 (en) * | 2013-06-13 | 2014-12-18 | Cannabis Science International Holding B.V. | Composition for the treatment of neurobehavioral disorders |
| US20160250270A1 (en) * | 2015-02-27 | 2016-09-01 | Ebbu, LLC | Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral |
Non-Patent Citations (1)
| Title |
|---|
| IZZO A A ET AL,, NON-PSYCHOTROPIC PLANT CANNABINOIDS: NEW THERAPEUTIC OPPORTUNITIES FROM AN ANCIENT HERB, 2 September 2009 (2009-09-02) * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019530751A (ja) | 2019-10-24 |
| WO2018071452A1 (en) | 2018-04-19 |
| JP2023058599A (ja) | 2023-04-25 |
| JP7225103B2 (ja) | 2023-02-20 |
| IL265902B1 (en) | 2023-12-01 |
| AU2025213702A1 (en) | 2025-09-04 |
| US20180098948A1 (en) | 2018-04-12 |
| US20200338017A1 (en) | 2020-10-29 |
| IL265902A (en) | 2019-06-30 |
| EP3525823B1 (en) | 2024-04-24 |
| AU2023222872A1 (en) | 2023-09-21 |
| US20250108016A1 (en) | 2025-04-03 |
| CN115887440A (zh) | 2023-04-04 |
| US10653640B2 (en) | 2020-05-19 |
| US11980592B2 (en) | 2024-05-14 |
| AU2017344040A1 (en) | 2019-04-18 |
| CN109963595B (zh) | 2023-02-03 |
| EP3525823A1 (en) | 2019-08-21 |
| CN109963595A (zh) | 2019-07-02 |
| CA3039413A1 (en) | 2018-04-19 |
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