IL259596A - A system and method for mapping functional nerves innervating the walls of arteries, their three-dimensional mapping and catheters for them - Google Patents

A system and method for mapping functional nerves innervating the walls of arteries, their three-dimensional mapping and catheters for them

Info

Publication number
IL259596A
IL259596A IL259596A IL25959618A IL259596A IL 259596 A IL259596 A IL 259596A IL 259596 A IL259596 A IL 259596A IL 25959618 A IL25959618 A IL 25959618A IL 259596 A IL259596 A IL 259596A
Authority
IL
Israel
Prior art keywords
mapping
catheters
arteries
same
nerves innervating
Prior art date
Application number
IL259596A
Other languages
English (en)
Hebrew (he)
Original Assignee
Symap Medical Suzhou Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/956,350 external-priority patent/US9820811B2/en
Application filed by Symap Medical Suzhou Ltd filed Critical Symap Medical Suzhou Ltd
Publication of IL259596A publication Critical patent/IL259596A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation
    • A61N1/36117Cardiac control, e.g. by vagal stimulation for treating hypertension
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/388Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4887Locating particular structures in or on the body
    • A61B5/4893Nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852Catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6876Blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056Transvascular endocardial electrode systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434Neural system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505Urinary tract
    • A61B2018/00511Kidney
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00839Bioelectrical parameters, e.g. ECG, EEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1407Loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/0215Measuring pressure in heart or blood vessels by means inserted into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Surgical Instruments (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
IL259596A 2015-12-01 2018-05-24 A system and method for mapping functional nerves innervating the walls of arteries, their three-dimensional mapping and catheters for them IL259596A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/956,350 US9820811B2 (en) 2011-08-26 2015-12-01 System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
PCT/IB2016/057258 WO2017093926A1 (en) 2015-12-01 2016-12-01 System and method for mapping functional nerves innervating wall of arteries,3-d mapping and catheters for same

Publications (1)

Publication Number Publication Date
IL259596A true IL259596A (en) 2018-07-31

Family

ID=58796408

Family Applications (1)

Application Number Title Priority Date Filing Date
IL259596A IL259596A (en) 2015-12-01 2018-05-24 A system and method for mapping functional nerves innervating the walls of arteries, their three-dimensional mapping and catheters for them

Country Status (11)

Country Link
EP (1) EP3383303B1 (enExample)
JP (2) JP7188752B2 (enExample)
KR (1) KR102799892B1 (enExample)
CN (1) CN108601616B (enExample)
AU (1) AU2016362114B2 (enExample)
CA (1) CA3006427A1 (enExample)
ES (1) ES2977410T3 (enExample)
IL (1) IL259596A (enExample)
SG (1) SG11201804191TA (enExample)
WO (1) WO2017093926A1 (enExample)
ZA (1) ZA201804115B (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3603501B1 (en) 2012-08-09 2025-07-23 University of Iowa Research Foundation Catheter systems for surrounding a tissue structure
EP3091921B1 (en) 2014-01-06 2019-06-19 Farapulse, Inc. Apparatus for renal denervation ablation
WO2015171921A2 (en) 2014-05-07 2015-11-12 Mickelson Steven R Methods and apparatus for selective tissue ablation
EP3142584A1 (en) 2014-05-16 2017-03-22 Iowa Approach Inc. Methods and apparatus for multi-catheter tissue ablation
EP3154463B1 (en) 2014-06-12 2019-03-27 Farapulse, Inc. Apparatus for rapid and selective transurethral tissue ablation
EP4559428A3 (en) 2014-06-12 2025-08-20 Boston Scientific Scimed, Inc. Method and apparatus for rapid and selective tissue ablation with cooling
EP3206613B1 (en) 2014-10-14 2019-07-03 Farapulse, Inc. Apparatus for rapid and safe pulmonary vein cardiac ablation
ES2977410T3 (es) * 2015-12-01 2024-08-23 Symap Medical Suzhou Ltd Sistema de mapeo de nervios funcionales que inervan la pared de las arterias, mapeo tridimensional y catéteres para los mismos
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
US20170189097A1 (en) 2016-01-05 2017-07-06 Iowa Approach Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US12144541B2 (en) 2016-01-05 2024-11-19 Boston Scientific Scimed, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US9987081B1 (en) 2017-04-27 2018-06-05 Iowa Approach, Inc. Systems, devices, and methods for signal generation
CN115844523A (zh) 2017-09-12 2023-03-28 波士顿科学医学有限公司 用于心室局灶性消融的系统、设备和方法
EP4275738B1 (en) 2018-02-08 2025-12-17 Boston Scientific Scimed, Inc. Apparatus for controlled delivery of pulsed electric field ablative energy to tissue
WO2019169446A1 (en) * 2018-03-09 2019-09-12 The University Of Sydney Response monitoring
US20190336198A1 (en) 2018-05-03 2019-11-07 Farapulse, Inc. Systems, devices, and methods for ablation using surgical clamps
WO2019217300A1 (en) 2018-05-07 2019-11-14 Farapulse, Inc. Epicardial ablation catheter
JP2021522903A (ja) 2018-05-07 2021-09-02 ファラパルス,インコーポレイテッド 組織へアブレーションエネルギーを送達するためのシステム、装置、および方法
WO2019217317A1 (en) 2018-05-07 2019-11-14 Farapulse, Inc. Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation
WO2020061359A1 (en) 2018-09-20 2020-03-26 Farapulse, Inc. Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
JP2022503833A (ja) * 2018-10-06 2022-01-12 サイマップ メディカル (スーチョウ), リミテッド 動脈の壁を神経支配する機能性神経をマッピングするためのシステムと方法、そのための3dマッピング、およびカテーテル
US12020791B2 (en) 2018-10-26 2024-06-25 Koninklijke Philips N.V. Determination of a treatment response index
EP3686898A1 (en) * 2019-01-24 2020-07-29 Koninklijke Philips N.V. Determination of a treatment response index
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines
CN113855173A (zh) * 2020-06-29 2021-12-31 上海形状记忆合金材料有限公司 电极导管系统
US12310652B2 (en) 2020-07-24 2025-05-27 Boston Scientific Scimed, Inc. Hybrid electroporation ablation catheter
EP4185228A1 (en) 2020-07-24 2023-05-31 Boston Scientific Scimed Inc. Electric field application for single shot cardiac ablation by irreversible electroporation
WO2022072385A2 (en) 2020-09-30 2022-04-07 Boston Scientific Scimed Inc Pretreatment waveform for irreversible electroporation
US12343071B2 (en) 2021-01-27 2025-07-01 Boston Scientific Scimed, Inc Voltage controlled pulse sequences for irreversible electroporation ablations
CN114052896A (zh) * 2021-12-17 2022-02-18 苏州润迈德医疗科技有限公司 一种消融导管效果参数测评方法和测评装置
CN116327347A (zh) * 2023-03-01 2023-06-27 上海佰川声生命科技有限公司 一种消融导管
WO2024242155A1 (ja) * 2023-05-23 2024-11-28 国立大学法人京都大学 コンピュータプログラム、心内心電図評価装置、心内心電図評価システム、心内心電図評価方法及び学習モデル生成方法
WO2025233150A1 (en) * 2024-05-08 2025-11-13 Medtronic Ireland Manufacturing Unlimited Company Neuromodulation catheter including stimulation and ablation electrodes

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010007070A1 (en) 1999-04-05 2001-07-05 Medtronic, Inc. Ablation catheter assembly and method for isolating a pulmonary vein
US7653438B2 (en) * 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20070135875A1 (en) * 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
WO2007001981A2 (en) * 2005-06-20 2007-01-04 Ablation Frontiers Ablation catheter
EP2092957B2 (en) * 2006-06-28 2019-11-20 Medtronic Ardian Luxembourg S.à.r.l. Systems for thermally-induced renal neuromodulation
US20120265198A1 (en) * 2010-11-19 2012-10-18 Crow Loren M Renal nerve detection and ablation apparatus and method
CN102198015B (zh) * 2011-05-03 2013-11-06 上海微创电生理医疗科技有限公司 可伸缩螺旋叠环式电极导管
US8702619B2 (en) 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
CN102949176B (zh) * 2011-08-26 2014-11-12 苏州信迈医疗器械有限公司 肾神经消融术中肾神经分布标测方法及用于该方法的导管
AU2012303696B2 (en) * 2011-08-26 2014-05-29 Symap Medical (Suzhou), Ltd System and method for locating and identifying functional nerves innervating wall of arteries
US9820811B2 (en) * 2011-08-26 2017-11-21 Symap Medical (Suzhou), Ltd System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
EP2775899B1 (en) * 2011-11-07 2017-08-23 Medtronic Ardian Luxembourg S.à.r.l. Endovascular nerve monitoring devices and associated systems
SG11201406006XA (en) * 2012-01-26 2014-11-27 Autonomix Medical Inc Controlled sympathectomy and micro-ablation systems and methods
US9173696B2 (en) * 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
KR101459941B1 (ko) * 2013-08-23 2014-11-07 고려대학교 산학협력단 다전극 맵핑 및 절제 카테터
JP2015112114A (ja) 2013-12-06 2015-06-22 株式会社グッドマン 神経電位測定用カテーテル
ES2977410T3 (es) * 2015-12-01 2024-08-23 Symap Medical Suzhou Ltd Sistema de mapeo de nervios funcionales que inervan la pared de las arterias, mapeo tridimensional y catéteres para los mismos

Also Published As

Publication number Publication date
JP2019505249A (ja) 2019-02-28
EP3383303A1 (en) 2018-10-10
EP3383303C0 (en) 2024-04-10
CA3006427A1 (en) 2017-06-08
WO2017093926A1 (en) 2017-06-08
ZA201804115B (en) 2019-04-24
EP3383303B1 (en) 2024-04-10
AU2016362114A1 (en) 2018-06-07
JP7188752B2 (ja) 2022-12-13
EP3383303A4 (en) 2019-07-31
JP2022017223A (ja) 2022-01-25
ES2977410T3 (es) 2024-08-23
SG11201804191TA (en) 2018-06-28
KR20180118600A (ko) 2018-10-31
KR102799892B1 (ko) 2025-04-23
CN108601616B (zh) 2022-04-12
JP7242090B2 (ja) 2023-03-20
AU2016362114B2 (en) 2020-07-16
CN108601616A (zh) 2018-09-28

Similar Documents

Publication Publication Date Title
ZA201804115B (en) System and method for mapping functional nerves innervating wall of arteries,3-d mapping and catheters for same
ZA202102911B (en) System and method for mapping functional nerves innervating wall of arteries, 3-d mapping and catheters for same
EP3359031A4 (en) METHOD AND SYSTEM FOR NEUROMODULATION AND STIMULATION
GB2535627B (en) Electrosurgical system
GB2561318B (en) System and method for mapping reservoir properties away from the wellbore
EP3212270A4 (en) Catheter system
EP3180080A4 (en) Brain stimulation system including multiple stimulation modes
EP3194003A4 (en) Vascular re-entry catheter
EP3145584A4 (en) Systems and methods for vagal nerve stimulation
EP3116583A4 (en) Indwelling body lumen expander
EP3119284A4 (en) Fluid therapy method
SG11201608878SA (en) Catheter and catheter system for electrical neuromodulation
EP3251051A4 (en) Localization and mapping method
EP3242620A4 (en) Tumor ablation system
IL256956B (en) Devices and methods for cardiac arrhythmia mapping
EP3145560A4 (en) Insert for catheter system
SG10201502401XA (en) Method of obfuscating data
EP3242717A4 (en) Cardiac modulation facilitation methods and systems
EP3256042A4 (en) Methods and systems for therapeutic neuromodulation
EP3195291A4 (en) Brain stimulation system and uses thereof
GB2536379B (en) Steerable drilling method and system
PL3201405T3 (pl) Układ zintegrowany, jego element złączny i sposób jego wytwarzania
EP3178386A4 (en) Catheter
EP3337554A4 (en) PROCESS FOR USING EPIDURAL ELECTRICAL STIMULATION
EP3089725A4 (en) Method and system for heart pacing