IL237541B - תרכובות בולאמפיפיליות, תכשירים ושימושים שלהן - Google Patents
תרכובות בולאמפיפיליות, תכשירים ושימושים שלהןInfo
- Publication number
- IL237541B IL237541B IL237541A IL23754115A IL237541B IL 237541 B IL237541 B IL 237541B IL 237541 A IL237541 A IL 237541A IL 23754115 A IL23754115 A IL 23754115A IL 237541 B IL237541 B IL 237541B
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- bolaamphiphilic compounds
- bolaamphiphilic
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261696789P | 2012-09-04 | 2012-09-04 | |
PCT/US2013/057956 WO2014039501A1 (en) | 2012-09-04 | 2013-09-04 | Bolaamphiphilic compounds, compositions and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
IL237541A0 IL237541A0 (he) | 2015-04-30 |
IL237541B true IL237541B (he) | 2019-07-31 |
Family
ID=50237566
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL237541A IL237541B (he) | 2012-09-04 | 2015-03-03 | תרכובות בולאמפיפיליות, תכשירים ושימושים שלהן |
IL267888A IL267888B (he) | 2012-09-04 | 2019-07-07 | תרכובות בולאמפיפיליות, תכשירים ושימושים שלהן |
IL280316A IL280316B (he) | 2012-09-04 | 2021-01-20 | תרכובות בולאמפיפיליות, תכשירים ושימוש שלהן |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL267888A IL267888B (he) | 2012-09-04 | 2019-07-07 | תרכובות בולאמפיפיליות, תכשירים ושימושים שלהן |
IL280316A IL280316B (he) | 2012-09-04 | 2021-01-20 | תרכובות בולאמפיפיליות, תכשירים ושימוש שלהן |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2892510A4 (he) |
AU (4) | AU2013312908A1 (he) |
CA (2) | CA2883784C (he) |
IL (3) | IL237541B (he) |
WO (1) | WO2014039501A1 (he) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016168580A1 (en) * | 2015-04-16 | 2016-10-20 | Lauren Sciences Llc | Bolaamphiphilic compounds, compositions and uses thereof |
JP2022552774A (ja) * | 2019-08-12 | 2022-12-20 | インテグレイテッド ナノセラピューティクス インコーポレイテッド | 荷電物質を送達する脂質、その製剤、およびその製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2478066C (en) * | 2001-12-04 | 2009-09-08 | Ben-Gurion University Of The Negev Research And Development Authority | Amphiphilic compounds and vesicles/liposomes for organ-specific drug targeting |
WO2006072943A2 (en) * | 2005-01-03 | 2006-07-13 | Ben Gurion University Of The Negev Research And Development Authority | Nano- and mesosized particles comprising an inorganic core, process and applications thereof |
EP2427175B1 (en) | 2009-05-04 | 2018-08-29 | Ben-gurion University Of The Negev Research And Development Authority | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery |
-
2013
- 2013-09-04 EP EP13834981.6A patent/EP2892510A4/en active Pending
- 2013-09-04 WO PCT/US2013/057956 patent/WO2014039501A1/en active Application Filing
- 2013-09-04 CA CA2883784A patent/CA2883784C/en active Active
- 2013-09-04 CA CA3233929A patent/CA3233929A1/en active Pending
- 2013-09-04 AU AU2013312908A patent/AU2013312908A1/en not_active Abandoned
-
2015
- 2015-03-03 IL IL237541A patent/IL237541B/he active IP Right Grant
-
2018
- 2018-06-06 AU AU2018203992A patent/AU2018203992B2/en active Active
-
2019
- 2019-07-07 IL IL267888A patent/IL267888B/he active IP Right Grant
-
2020
- 2020-05-27 AU AU2020203496A patent/AU2020203496B2/en active Active
-
2021
- 2021-01-20 IL IL280316A patent/IL280316B/he unknown
-
2022
- 2022-01-27 AU AU2022200494A patent/AU2022200494A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2018203992A1 (en) | 2018-06-21 |
AU2013312908A1 (en) | 2015-03-26 |
EP2892510A1 (en) | 2015-07-15 |
IL267888B (he) | 2021-02-28 |
EP2892510A4 (en) | 2016-06-01 |
AU2020203496A1 (en) | 2020-06-18 |
AU2020203496B2 (en) | 2021-10-28 |
WO2014039501A1 (en) | 2014-03-13 |
IL280316B (he) | 2021-08-31 |
IL280316A (he) | 2021-03-01 |
CA2883784A1 (en) | 2014-03-13 |
AU2018203992B2 (en) | 2020-02-27 |
IL237541A0 (he) | 2015-04-30 |
CA2883784C (en) | 2024-05-14 |
AU2022200494A1 (en) | 2022-02-24 |
IL267888A (he) | 2019-09-26 |
CA3233929A1 (en) | 2014-03-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |