IL218565A0 - Polymorphic and pseudopolymorphic forms of a pharmaceutical compound - Google Patents

Polymorphic and pseudopolymorphic forms of a pharmaceutical compound

Info

Publication number
IL218565A0
IL218565A0 IL218565A IL21856512A IL218565A0 IL 218565 A0 IL218565 A0 IL 218565A0 IL 218565 A IL218565 A IL 218565A IL 21856512 A IL21856512 A IL 21856512A IL 218565 A0 IL218565 A0 IL 218565A0
Authority
IL
Israel
Prior art keywords
polymorphic
pharmaceutical compound
pseudopolymorphic forms
pseudopolymorphic
forms
Prior art date
Application number
IL218565A
Original Assignee
Novexel Sa
Forest Lab Holding Ltd
Sisir Bhattacharya
Alain Bonnet
Mahendra G Dedhiya
Alexandre Giuliani
Alain Priour
Valerie Ravaux
Peter Spargo
Veronique Ducandas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42154208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL218565(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novexel Sa, Forest Lab Holding Ltd, Sisir Bhattacharya, Alain Bonnet, Mahendra G Dedhiya, Alexandre Giuliani, Alain Priour, Valerie Ravaux, Peter Spargo, Veronique Ducandas filed Critical Novexel Sa
Publication of IL218565A0 publication Critical patent/IL218565A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL218565A 2009-10-09 2012-03-08 Polymorphic and pseudopolymorphic forms of a pharmaceutical compound IL218565A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0904864A FR2951171A1 (en) 2009-10-09 2009-10-09 NOVEL SODIUM SALT OF A CRYSTALLIZED ENANTIOMER AZABICYCLIC COMPOUND AND NOVEL POLYMORPHIC AND PSEUDOPOLYMORPHIC FORMS AND THEIR PREPARATION
US26366309P 2009-11-23 2009-11-23
PCT/EP2010/065147 WO2011042560A1 (en) 2009-10-09 2010-10-08 Polymorphic and pseudopolymorphic forms of a pharmaceutical compound

Publications (1)

Publication Number Publication Date
IL218565A0 true IL218565A0 (en) 2012-05-31

Family

ID=42154208

Family Applications (3)

Application Number Title Priority Date Filing Date
IL218565A IL218565A0 (en) 2009-10-09 2012-03-08 Polymorphic and pseudopolymorphic forms of a pharmaceutical compound
IL239663A IL239663A0 (en) 2009-10-09 2015-06-25 Polymorphic and pseudopolymorphic forms of a pharmaceutical compound
IL259296A IL259296B (en) 2009-10-09 2018-05-13 Sodium salt of (1r,2s,5r)-7-oxo-6-sulfooxy-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL239663A IL239663A0 (en) 2009-10-09 2015-06-25 Polymorphic and pseudopolymorphic forms of a pharmaceutical compound
IL259296A IL259296B (en) 2009-10-09 2018-05-13 Sodium salt of (1r,2s,5r)-7-oxo-6-sulfooxy-1,6-diazabicyclo[3.2.1]octane-2-carboxamide

Country Status (22)

Country Link
US (5) US8471025B2 (en)
EP (3) EP3269717B9 (en)
JP (4) JP6072540B2 (en)
KR (4) KR20180067717A (en)
CN (3) CN104592229A (en)
AU (1) AU2010304974B2 (en)
BR (2) BR122019021689B8 (en)
CA (1) CA2716914C (en)
CY (1) CY1121583T1 (en)
DK (1) DK3269717T5 (en)
ES (2) ES2721228T5 (en)
FI (1) FI3269717T4 (en)
FR (1) FR2951171A1 (en)
HU (1) HUE043086T2 (en)
IL (3) IL218565A0 (en)
MX (1) MX2012003730A (en)
MY (1) MY174776A (en)
PL (1) PL3269717T5 (en)
PT (1) PT3269717T (en)
RU (1) RU2727509C2 (en)
SI (1) SI3269717T2 (en)
WO (1) WO2011042560A1 (en)

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US8247400B2 (en) * 2009-02-23 2012-08-21 Dedhiya Mahendra G Cephem compounds useful for the treatment of bacterial infections
US8772490B2 (en) 2010-12-22 2014-07-08 Meiji Seika Pharma Co., Ltd. Optically active diazabicyclooctane derivatives and process for preparing the same
DK2657234T3 (en) * 2010-12-22 2017-02-20 Meiji Seika Pharma Co Ltd Optically active diazabicyclooctane derivative and process for its preparation
EP2721005B1 (en) * 2011-06-17 2015-11-25 AstraZeneca AB Process for preparing heterocyclic compounds including trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide and salts thereof
CA2842777C (en) * 2011-07-26 2015-12-29 Wockhardt Limited Pharmaceutical compositions comprising sulbactam and beta-lactamase inhibitor
CN103619843B (en) * 2011-08-27 2017-01-11 沃克哈特有限公司 1,6-diazabicyclo[3,2,1]octan-7-one derivatives and use thereof in treating bacterial infections
US8969567B2 (en) 2011-09-13 2015-03-03 Wockhardt Ltd. Nitrogen containing compounds and their use
AU2012310136B2 (en) 2011-09-13 2016-07-07 Wockhardt Limited Nitrogen containing compounds and their use
TW201343645A (en) 2012-03-30 2013-11-01 Cubist Pharm Inc 1,3,4-oxadiazole and 1,3,4-thiadiazole β-lactamase inhibitors
US8916709B2 (en) 2012-03-30 2014-12-23 Cubist Pharmaceuticals, Inc. 1,2,4-oxadiazole and 1,2,4-thiadiazole β-lactamase inhibitors
US8969570B2 (en) 2012-03-30 2015-03-03 Cubist Pharmaceuticals, Inc. Beta-lactamase inhibitors
EP2831069B1 (en) 2012-03-30 2017-07-12 Merck Sharp & Dohme Corp. Isoxazole beta-lactamase inhibitors
AR090539A1 (en) 2012-04-02 2014-11-19 Astrazeneca Ab INHIBITING COMPOUNDS OF B LACTAMASA
AR091222A1 (en) 2012-05-30 2015-01-21 Meiji Seika Pharma Co Ltd B-LACTAMASE INHIBITOR AND PROCESS TO PREPARE
BR112015021186A2 (en) * 2013-03-08 2017-07-18 Wockhardt Ltd process for the preparation of (2s, 5r) -7-oxo-6-sulfoxy-2 - [((3r) -pyrrolidine-3-carbonyl) hydrazino carbonyl] -1,6-diaza-bicyclo [3.2.1] octane
AU2013380573B2 (en) * 2013-03-08 2016-07-07 Wockhardt Limited A process for sodium salt of (2S, 5R)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane
US9120795B2 (en) 2013-03-14 2015-09-01 Cubist Pharmaceuticals, Inc. Crystalline form of a β-lactamase inhibitor
JP6453222B2 (en) 2013-09-24 2019-01-16 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 Preparation of diazabicyclooctane derivatives and their intermediates
US9120796B2 (en) 2013-10-02 2015-09-01 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
NZ757220A (en) 2013-10-08 2021-12-24 Meiji Seika Pharma Co Ltd Crystalline forms of diazabicyclooctane derivative and production process thereof
CN106029068A (en) * 2014-02-20 2016-10-12 沃克哈特有限公司 Pharmaceutical combinations comprising antibacterial agents
EP3212238A1 (en) 2014-10-28 2017-09-06 Sandoz AG Pharmaceutical composition consisting of ceftaroline fosamil acetic acid solvate particles and arginine particles, both having a specific particle size distribution
CN107108624B (en) 2014-11-17 2020-01-07 恩塔西斯治疗有限公司 Combination therapy for the treatment of drug resistant bacterial infections
MX2017007191A (en) 2014-12-05 2017-08-28 Meiji Seika Pharma Co Ltd Method for producing crystals of diazabicyclooctane derivative and stable lyophilized preparation.
CN107922411B (en) * 2015-08-10 2021-07-02 桑多斯股份公司 Crystal form C of avibactam sodium
CN107325096B (en) * 2016-04-29 2020-11-03 正大天晴药业集团股份有限公司 Crystallization of avibactam monosodium salt
JP7183147B2 (en) * 2016-08-26 2022-12-05 サンド アクツィエンゲゼルシャフト Avibactam free acid
LT3512851T (en) 2016-09-16 2022-10-25 Entasis Therapeutics Limited Beta-lactamase inhibitor compounds
CN107880042A (en) * 2016-09-30 2018-04-06 上海复星星泰医药科技有限公司 The preparation method of AVM hereinafter Batan sodium and its midbody compound
AU2018219569B2 (en) * 2017-02-08 2021-11-11 Sandoz Ag Process for the preparation of crystalline form C of avibactam sodium
ES2907858T3 (en) 2017-05-08 2022-04-26 Entasis Therapeutics Inc Compounds and methods for the treatment of bacterial infections
KR20200091396A (en) * 2017-09-27 2020-07-30 페도라 파마슈티칼스 인코포레이티드 Pharmaceutical form of diazabicyclooctane derivative and method for preparing the same
WO2019064066A1 (en) * 2017-09-27 2019-04-04 F. Hoffmann-La Roche Ag Pharmaceutical forms of diazabicyclooctane derivatives and manufacturing method thereof
EP3687992A1 (en) * 2017-09-27 2020-08-05 Meiji Seika Pharma Co., Ltd. Crystalline forms of diazabicyclooctane derivatives and production process thereof
CN107501265B (en) * 2017-10-09 2019-05-28 台州职业技术学院 A kind of 7- oxo-diazabicylo [3,2,1] octane derivatives compound and its preparation method and application
CN109678856B (en) 2017-10-18 2020-09-25 新发药业有限公司 Preparation method of avibactam intermediate
CN107827886B (en) * 2017-11-23 2020-06-23 中山奕安泰医药科技有限公司 Refining preparation process of high-purity abamectin
CN109956941B (en) 2017-12-25 2020-08-04 新发药业有限公司 Simple preparation method of abamectin
CN107935945A (en) * 2018-01-12 2018-04-20 上海龙翔生物医药开发有限公司 A kind of method that crystal form A or crystal form D AVM hereinafter Batan products are prepared by reaction
CN107936017A (en) * 2018-01-12 2018-04-20 上海龙翔生物医药开发有限公司 A kind of method that crystal form A or crystal form D AVM hereinafter Batan products are prepared by crystallization
CN110078728B (en) * 2019-05-23 2020-10-23 江西富祥药业股份有限公司 Abamebactam intermediate, preparation method and application thereof
CN113105455B (en) * 2020-01-10 2024-05-17 四川科伦药物研究院有限公司 Preparation method of crystal form B avibactam sodium
CN111689964A (en) * 2020-07-21 2020-09-22 海南海灵化学制药有限公司 Stable crystal form of abamectin sodium and preparation method thereof
CN114249729A (en) * 2020-09-23 2022-03-29 四川科伦药物研究院有限公司 Method for preparing crystal form B avibactam sodium through reaction crystallization
CN115677697A (en) * 2022-09-19 2023-02-03 瑞阳制药股份有限公司 Crystallization method of B crystal form abamectin sodium with adjustable particle size and good fluidity
KR20240041506A (en) * 2022-09-23 2024-04-01 주식회사 경보제약 Stable monohydrate form of avibactam sodium and manufacturaing method thereof

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TW473479B (en) * 1997-12-19 2002-01-21 Takeda Chemical Industries Ltd Phosphonocephem derivatives, their production and use
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FR2835186B1 (en) * 2002-01-28 2006-10-20 Aventis Pharma Sa NOVEL HETEROCYCLIC COMPOUNDS ACTIVE AS BETA-LACTAMASES INHIBITORS
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FR2921060B1 (en) 2007-09-14 2012-06-15 Novexel NOVEL PROCESS FOR PREPARING DISUBSIDED PIPERIDINE AND NOVEL INTERMEDIATES
EP2921559A1 (en) † 2008-06-19 2015-09-23 Astra Zeneca Holding France Use of (1r,2s,5r) 1,6-diazabicyclo [3.2.1]octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases
EA029149B1 (en) * 2009-09-21 2018-02-28 Пфайзер Анти-Инфективз Аб Pharmaceutical compositions comprising ceftaroline fosamil for treating bacterial infections

Also Published As

Publication number Publication date
BR122019021689B8 (en) 2021-05-25
IL259296B (en) 2021-10-31
CA2716914C (en) 2020-10-27
PL3269717T5 (en) 2023-09-18
KR20120106720A (en) 2012-09-26
SI3269717T2 (en) 2023-09-29
BR122019021689B1 (en) 2020-10-27
PL3269717T3 (en) 2019-07-31
EP2486038A1 (en) 2012-08-15
EP3269717B2 (en) 2023-06-14
ES2721228T5 (en) 2023-10-30
CY1121583T1 (en) 2020-05-29
JP2017149754A (en) 2017-08-31
JP2013507346A (en) 2013-03-04
IL239663A0 (en) 2015-08-31
US20130267480A1 (en) 2013-10-10
US20170210742A1 (en) 2017-07-27
AU2010304974A1 (en) 2012-04-05
JP6197170B2 (en) 2017-09-20
KR20170134791A (en) 2017-12-06
FI3269717T4 (en) 2023-08-31
DK3269717T5 (en) 2023-11-27
EP3269717A1 (en) 2018-01-17
RU2012118247A (en) 2013-11-20
EP2486038B1 (en) 2017-08-30
EP3269717B9 (en) 2023-08-09
US8835455B2 (en) 2014-09-16
US9580424B2 (en) 2017-02-28
CA2716914A1 (en) 2011-04-09
KR20200010586A (en) 2020-01-30
ES2721228T3 (en) 2019-07-29
EP3269717B1 (en) 2019-02-27
IL259296A (en) 2018-07-31
HUE043086T2 (en) 2019-08-28
MX2012003730A (en) 2012-10-03
KR101817811B1 (en) 2018-01-11
WO2011042560A1 (en) 2011-04-14
CN102834395A (en) 2012-12-19
EP3505518A1 (en) 2019-07-03
JP6321853B2 (en) 2018-05-09
MY174776A (en) 2020-05-14
JP2016029082A (en) 2016-03-03
US9062053B2 (en) 2015-06-23
CN104592229A (en) 2015-05-06
JP6630391B2 (en) 2020-01-15
PT3269717T (en) 2019-05-16
BR112012007976B1 (en) 2020-03-03
CN102834395B (en) 2016-06-29
US20140349967A1 (en) 2014-11-27
KR20180067717A (en) 2018-06-20
US20110152311A1 (en) 2011-06-23
DK3269717T3 (en) 2019-04-23
JP6072540B2 (en) 2017-02-01
AU2010304974B2 (en) 2014-10-23
US20150246920A1 (en) 2015-09-03
CN109824668A (en) 2019-05-31
JP2018123151A (en) 2018-08-09
ES2645110T3 (en) 2017-12-04
US8471025B2 (en) 2013-06-25
RU2727509C2 (en) 2020-07-22
RU2015137928A (en) 2018-12-25
FR2951171A1 (en) 2011-04-15
DK3269717T4 (en) 2023-06-26
RU2015137928A3 (en) 2019-04-04
SI3269717T1 (en) 2019-05-31

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