IL201192A - Mek ligands and polynucleotides that bind to mek ligands - Google Patents
Mek ligands and polynucleotides that bind to mek ligandsInfo
- Publication number
- IL201192A IL201192A IL201192A IL20119209A IL201192A IL 201192 A IL201192 A IL 201192A IL 201192 A IL201192 A IL 201192A IL 20119209 A IL20119209 A IL 20119209A IL 201192 A IL201192 A IL 201192A
- Authority
- IL
- Israel
- Prior art keywords
- ligands
- mek
- mek ligands
- polynucleotides encoding
- polynucleotides
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 2
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11024—Mitogen-activated protein kinase (2.7.11.24), i.e. MAPK or MAPK2 or c-Jun N-terminal kinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/12—Dual-specificity kinases (2.7.12)
- C12Y207/12002—Mitogen-activated protein kinase kinase (2.7.12.2), i.e. MAPKK or MEK1 or MEK2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90823107P | 2007-03-27 | 2007-03-27 | |
| PCT/US2008/058531 WO2008119058A2 (en) | 2007-03-27 | 2008-03-27 | Mek ligands and polynucleotides encoding mek ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL201192A0 IL201192A0 (en) | 2011-08-01 |
| IL201192A true IL201192A (en) | 2014-11-30 |
Family
ID=39789285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL201192A IL201192A (en) | 2007-03-27 | 2009-09-24 | Mek ligands and polynucleotides that bind to mek ligands |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8575304B2 (enExample) |
| EP (2) | EP2126064B1 (enExample) |
| JP (1) | JP5611814B2 (enExample) |
| KR (1) | KR101557167B1 (enExample) |
| CN (1) | CN101679956A (enExample) |
| AU (1) | AU2008230711B9 (enExample) |
| CA (1) | CA2680837C (enExample) |
| DK (1) | DK2126064T3 (enExample) |
| ES (1) | ES2390156T3 (enExample) |
| IL (1) | IL201192A (enExample) |
| WO (1) | WO2008119058A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8153598B2 (en) | 2005-10-19 | 2012-04-10 | Intrexon Corporation | PKD ligands and polynucleotides encoding PKD ligands |
| US7943732B2 (en) | 2006-06-05 | 2011-05-17 | Intrexon Corporation | AKT ligands and polynucleotides encoding AKT ligands |
| US8993263B2 (en) | 2006-08-07 | 2015-03-31 | Intrexon Corporation | PKA ligands and polynucleotides encoding PKA ligands |
| US8999666B2 (en) | 2006-08-09 | 2015-04-07 | Intrexon Corporation | PKC ligands and polynucleotides encoding PKC ligands |
| US8729225B2 (en) | 2006-11-13 | 2014-05-20 | Intrexon Corporation | Glycogen synthase kinase heteropolyligand polypeptide |
| US8283445B2 (en) | 2006-11-13 | 2012-10-09 | Intrexon Corporation | Extracellular-signal-regulated-kinase (ERK) heteropolyligand polypeptide |
| US7705122B2 (en) | 2006-12-04 | 2010-04-27 | Intrexon Corporation | mTOR ligands and polynucleotides encoding mTOR ligands |
| US8575304B2 (en) | 2007-03-27 | 2013-11-05 | Intrexon Corporation | MEK ligands and polynucleotides encoding MEK ligands |
| CA2685592C (en) | 2007-05-02 | 2018-08-07 | Intrexon Corporation | Pp1 ligands |
| US8431363B2 (en) * | 2008-01-09 | 2013-04-30 | Intrexon Corporation | Polynucleotides encoding therapeutic inhibitors of PAI-1 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9904395D0 (en) | 1999-02-25 | 1999-04-21 | Fluorescience Ltd | Protein assay |
| AUPR230500A0 (en) * | 2000-12-22 | 2001-01-25 | University Of Newcastle Research Associates Limited, The | A method of modulating map kinase mediated cellular activity and agents useful in same |
| US20050089932A1 (en) | 2001-04-26 | 2005-04-28 | Avidia Research Institute | Novel proteins with targeted binding |
| AU2002348791A1 (en) * | 2001-12-21 | 2003-07-09 | Warner-Lambert Company Llc | Modified mek1 and mek2, crystal of a peptide: ligand: cofactor complex containing such modified mek1 or mek2, and methods of use thereof |
| AU2003245627A1 (en) * | 2002-06-21 | 2004-01-06 | Incyte Corporation | Kinases and phosphatases |
| US7785871B2 (en) | 2002-10-09 | 2010-08-31 | Intrexon Corporation | DNA cloning vector plasmids and methods for their use |
| US20080050808A1 (en) | 2002-10-09 | 2008-02-28 | Reed Thomas D | DNA modular cloning vector plasmids and methods for their use |
| US7071295B2 (en) | 2002-12-02 | 2006-07-04 | Intrexon Corporation | Signal for targeting molecules to the sarco(endo)plasmic reticulum |
| US20080220497A1 (en) | 2003-12-24 | 2008-09-11 | Flynn Daniel L | Modulation of protein functionalities |
| WO2005113812A2 (en) * | 2004-04-23 | 2005-12-01 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| CN1981047B (zh) | 2004-05-18 | 2013-08-21 | 英特拉克森公司 | Dna克隆载体质粒的动态载体装配方法 |
| WO2006039367A2 (en) * | 2004-10-01 | 2006-04-13 | Mount Sinai School Of Medicine Of New York University | Resonance energy transfer system and method |
| WO2007048103A2 (en) | 2006-10-18 | 2007-04-26 | Intrexon Corporation | Pkd ligands and polynucleotides encoding pkd ligands |
| US8153598B2 (en) | 2005-10-19 | 2012-04-10 | Intrexon Corporation | PKD ligands and polynucleotides encoding PKD ligands |
| US7943732B2 (en) | 2006-06-05 | 2011-05-17 | Intrexon Corporation | AKT ligands and polynucleotides encoding AKT ligands |
| US8993263B2 (en) | 2006-08-07 | 2015-03-31 | Intrexon Corporation | PKA ligands and polynucleotides encoding PKA ligands |
| US8999666B2 (en) | 2006-08-09 | 2015-04-07 | Intrexon Corporation | PKC ligands and polynucleotides encoding PKC ligands |
| US8283445B2 (en) | 2006-11-13 | 2012-10-09 | Intrexon Corporation | Extracellular-signal-regulated-kinase (ERK) heteropolyligand polypeptide |
| US8729225B2 (en) | 2006-11-13 | 2014-05-20 | Intrexon Corporation | Glycogen synthase kinase heteropolyligand polypeptide |
| US7705122B2 (en) | 2006-12-04 | 2010-04-27 | Intrexon Corporation | mTOR ligands and polynucleotides encoding mTOR ligands |
| US7927987B2 (en) | 2007-03-27 | 2011-04-19 | Texas Instruments Incorporated | Method of reducing channeling of ion implants using a sacrificial scattering layer |
| US8575304B2 (en) | 2007-03-27 | 2013-11-05 | Intrexon Corporation | MEK ligands and polynucleotides encoding MEK ligands |
-
2008
- 2008-03-27 US US12/532,912 patent/US8575304B2/en not_active Expired - Fee Related
- 2008-03-27 ES ES08744516T patent/ES2390156T3/es active Active
- 2008-03-27 EP EP08744516A patent/EP2126064B1/en not_active Not-in-force
- 2008-03-27 JP JP2010501233A patent/JP5611814B2/ja not_active Expired - Fee Related
- 2008-03-27 WO PCT/US2008/058531 patent/WO2008119058A2/en not_active Ceased
- 2008-03-27 AU AU2008230711A patent/AU2008230711B9/en not_active Ceased
- 2008-03-27 DK DK08744516.9T patent/DK2126064T3/da active
- 2008-03-27 CA CA2680837A patent/CA2680837C/en not_active Expired - Fee Related
- 2008-03-27 EP EP12170618.8A patent/EP2537924B1/en not_active Ceased
- 2008-03-27 CN CN200880017643A patent/CN101679956A/zh active Pending
- 2008-03-27 KR KR1020097022413A patent/KR101557167B1/ko not_active Expired - Fee Related
-
2009
- 2009-09-24 IL IL201192A patent/IL201192A/en active IP Right Grant
-
2013
- 2013-10-04 US US14/046,454 patent/US9006390B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK2126064T3 (da) | 2012-09-10 |
| HK1138876A1 (en) | 2010-09-03 |
| AU2008230711B2 (en) | 2014-03-27 |
| WO2008119058A9 (en) | 2008-12-24 |
| EP2537924B1 (en) | 2015-03-18 |
| EP2537924A2 (en) | 2012-12-26 |
| US9006390B2 (en) | 2015-04-14 |
| EP2537924A3 (en) | 2013-04-10 |
| WO2008119058A2 (en) | 2008-10-02 |
| EP2126064A2 (en) | 2009-12-02 |
| JP5611814B2 (ja) | 2014-10-22 |
| AU2008230711A1 (en) | 2008-10-02 |
| US20140073028A1 (en) | 2014-03-13 |
| CA2680837C (en) | 2017-06-06 |
| IL201192A0 (en) | 2011-08-01 |
| CA2680837A1 (en) | 2008-10-02 |
| KR20100015944A (ko) | 2010-02-12 |
| KR101557167B1 (ko) | 2015-10-02 |
| CN101679956A (zh) | 2010-03-24 |
| WO2008119058A3 (en) | 2009-02-12 |
| EP2126064A4 (en) | 2010-06-23 |
| US8575304B2 (en) | 2013-11-05 |
| EP2126064B1 (en) | 2012-06-06 |
| AU2008230711B9 (en) | 2014-08-21 |
| JP2010522568A (ja) | 2010-07-08 |
| ES2390156T3 (es) | 2012-11-07 |
| US20100279378A1 (en) | 2010-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |