IL200672A - זרע המכיל תוליום לטיפול בברכיתרפיה במינון נמוך - Google Patents
זרע המכיל תוליום לטיפול בברכיתרפיה במינון נמוךInfo
- Publication number
- IL200672A IL200672A IL200672A IL20067209A IL200672A IL 200672 A IL200672 A IL 200672A IL 200672 A IL200672 A IL 200672A IL 20067209 A IL20067209 A IL 20067209A IL 200672 A IL200672 A IL 200672A
- Authority
- IL
- Israel
- Prior art keywords
- thulium
- radiation
- gold
- low dose
- kev
- Prior art date
Links
- 229910052775 Thulium Inorganic materials 0.000 title claims description 63
- 238000002725 brachytherapy Methods 0.000 title claims description 36
- FRNOGLGSGLTDKL-UHFFFAOYSA-N thulium atom Chemical compound [Tm] FRNOGLGSGLTDKL-UHFFFAOYSA-N 0.000 title description 46
- 230000005855 radiation Effects 0.000 claims description 98
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 63
- 239000010931 gold Substances 0.000 claims description 57
- 229910052737 gold Inorganic materials 0.000 claims description 56
- 238000000576 coating method Methods 0.000 claims description 47
- 239000011248 coating agent Substances 0.000 claims description 45
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 37
- 239000010936 titanium Substances 0.000 claims description 36
- 229910052719 titanium Inorganic materials 0.000 claims description 35
- 229910052751 metal Inorganic materials 0.000 claims description 34
- 239000002184 metal Substances 0.000 claims description 34
- 230000000694 effects Effects 0.000 claims description 32
- FRNOGLGSGLTDKL-OUBTZVSYSA-N thulium-170 Chemical compound [170Tm] FRNOGLGSGLTDKL-OUBTZVSYSA-N 0.000 claims description 24
- 238000001228 spectrum Methods 0.000 claims description 20
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 15
- 229910052697 platinum Inorganic materials 0.000 claims description 8
- 238000000295 emission spectrum Methods 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 3
- 208000037656 Respiratory Sounds Diseases 0.000 claims 3
- 206010037833 rales Diseases 0.000 claims 3
- 230000004913 activation Effects 0.000 description 23
- 229910001385 heavy metal Inorganic materials 0.000 description 22
- 206010028980 Neoplasm Diseases 0.000 description 19
- 239000010410 layer Substances 0.000 description 16
- 230000002285 radioactive effect Effects 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 239000002775 capsule Substances 0.000 description 12
- 230000004907 flux Effects 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
- 239000011133 lead Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 206010060862 Prostate cancer Diseases 0.000 description 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 239000011247 coating layer Substances 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 238000003466 welding Methods 0.000 description 3
- VWQVUPCCIRVNHF-OUBTZVSYSA-N Yttrium-90 Chemical compound [90Y] VWQVUPCCIRVNHF-OUBTZVSYSA-N 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000003708 ampul Substances 0.000 description 2
- 229910052786 argon Inorganic materials 0.000 description 2
- 230000005250 beta ray Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 238000009713 electroplating Methods 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 229910052745 lead Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 239000010453 quartz Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 229910000497 Amalgam Inorganic materials 0.000 description 1
- 241001457926 Brachys Species 0.000 description 1
- 230000005461 Bremsstrahlung Effects 0.000 description 1
- 208000009849 Female Genital Neoplasms Diseases 0.000 description 1
- 229910001200 Ferrotitanium Inorganic materials 0.000 description 1
- 229920005479 Lucite® Polymers 0.000 description 1
- 238000002083 X-ray spectrum Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000012300 argon atmosphere Substances 0.000 description 1
- 230000005255 beta decay Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001730 gamma-ray spectroscopy Methods 0.000 description 1
- -1 gold ions Chemical class 0.000 description 1
- 208000014829 head and neck neoplasm Diseases 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 229910052741 iridium Inorganic materials 0.000 description 1
- 238000005372 isotope separation Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N palladium Substances [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000010944 silver (metal) Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 238000004846 x-ray emission Methods 0.000 description 1
Landscapes
- Radiation-Therapy Devices (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL200672A IL200672A (he) | 2007-03-12 | 2009-09-01 | זרע המכיל תוליום לטיפול בברכיתרפיה במינון נמוך |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90620407P | 2007-03-12 | 2007-03-12 | |
| PCT/IL2008/000338 WO2008111065A1 (en) | 2007-03-12 | 2008-03-12 | Thulium-containing low dose rate brachytherapy seed |
| IL200672A IL200672A (he) | 2007-03-12 | 2009-09-01 | זרע המכיל תוליום לטיפול בברכיתרפיה במינון נמוך |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL200672A0 IL200672A0 (en) | 2010-05-17 |
| IL200672A true IL200672A (he) | 2012-09-24 |
Family
ID=42263581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL200672A IL200672A (he) | 2007-03-12 | 2009-09-01 | זרע המכיל תוליום לטיפול בברכיתרפיה במינון נמוך |
Country Status (1)
| Country | Link |
|---|---|
| IL (1) | IL200672A (he) |
-
2009
- 2009-09-01 IL IL200672A patent/IL200672A/he not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL200672A0 (en) | 2010-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |