IL199882A - Cyclohexenone compounds from antrodia camphorata and pharmaceutical composiitons comprising them - Google Patents

Cyclohexenone compounds from antrodia camphorata and pharmaceutical composiitons comprising them

Info

Publication number
IL199882A
IL199882A IL199882A IL19988209A IL199882A IL 199882 A IL199882 A IL 199882A IL 199882 A IL199882 A IL 199882A IL 19988209 A IL19988209 A IL 19988209A IL 199882 A IL199882 A IL 199882A
Authority
IL
Israel
Prior art keywords
growth
compound
tumour cells
composiitons
pharmaceutical
Prior art date
Application number
IL199882A
Other languages
Hebrew (he)
Other versions
IL199882A0 (en
Original Assignee
Golden Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Golden Biotechnology Corp filed Critical Golden Biotechnology Corp
Publication of IL199882A0 publication Critical patent/IL199882A0/en
Publication of IL199882A publication Critical patent/IL199882A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to a novel compound and its use, especially to 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone), which is separated from an extractant of Antrodia camphorate, and its use is in inhibiting the growth of tumour cells. The so-called compound of the present invention is found in Antrodia camphorate for the first time, and it may be used to inhibit the growth of tumour cells of breast cancer, liver cancer and prostate cancer. Meanwhile, the so-called compound may be used as a component of a pharmaceutical composition for inhibition of the growth of tumour cells above, or as that compound has the activity of anti-oxidation, it can further be used for prevention of cardiovascular disease or be added into health protection potables and foodstuff.
IL199882A 2007-01-18 2009-07-15 Cyclohexenone compounds from antrodia camphorata and pharmaceutical composiitons comprising them IL199882A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2007100042358A CN101225066B (en) 2007-01-18 2007-01-18 Cyclohexenone extract of antrodia camphorata
PCT/CN2008/070071 WO2008089674A1 (en) 2007-01-18 2008-01-10 Cyclohexenone extractant of antrodia camphorata

Publications (2)

Publication Number Publication Date
IL199882A0 IL199882A0 (en) 2010-04-15
IL199882A true IL199882A (en) 2013-09-30

Family

ID=39644119

Family Applications (1)

Application Number Title Priority Date Filing Date
IL199882A IL199882A (en) 2007-01-18 2009-07-15 Cyclohexenone compounds from antrodia camphorata and pharmaceutical composiitons comprising them

Country Status (5)

Country Link
CN (1) CN101225066B (en)
IL (1) IL199882A (en)
RU (1) RU2422431C2 (en)
UA (1) UA97135C2 (en)
WO (1) WO2008089674A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI394575B (en) * 2007-07-09 2013-05-01 Golden Biotechnology Corp Application of Cynanchum auranthone Cyclohexenone Compounds in the Preparation of Drugs for the Suppression of Hepatitis B
CN102000046B (en) * 2009-09-02 2012-05-30 国鼎生物科技股份有限公司 Application of antrodia camphorata cyclohexenone compound in preparing medicine for inhibiting growth of pancreatic cancer tumor cells
CN102232946B (en) * 2010-05-05 2013-01-16 国鼎生物科技股份有限公司 Use of antrodia camphorata cyclohexenone compound in preparing medicine for inhibiting stomach cancer tumor cell growth
CN102232945B (en) * 2010-05-05 2013-03-06 国鼎生物科技股份有限公司 Antrodia camphorata cyclohexenone compound for suppressing growth of bladder cancer tumor cells
CN102232942B (en) * 2010-05-06 2013-03-27 国鼎生物科技股份有限公司 Antrodia camphorata cyclohexenone compound for suppressing growth of lymphoma tumor cells
CN102232941B (en) * 2010-05-06 2013-03-27 国鼎生物科技股份有限公司 Antrodia camphorata cyclohexenone compound for inhibiting ovarian cancer tumor cell growth
CN102232940B (en) * 2010-05-06 2013-03-27 国鼎生物科技股份有限公司 Antrodia camphorata cyclohexenone compound for inhibiting colorectal cancer tumor cell growth
CN102232943B (en) * 2010-05-06 2013-03-20 国鼎生物科技股份有限公司 Antrodia camphorata cyclohexenone compound for inhibiting skin cancer tumor cell growth
US8309611B2 (en) * 2010-09-20 2012-11-13 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
CN103251658B (en) * 2012-02-21 2015-11-25 乔本生医股份有限公司 Antrodia Camphorata extraction concentrate and manufacture method thereof
SE1350211A1 (en) 2012-02-23 2013-08-24 Golden Biotechnology Corp Methods and compositions for the treatment of cancer metastases
AU2013239861A1 (en) * 2012-03-26 2014-09-25 Golden Biotechnology Corporation Methods and compositions for treating arteriosclerotic vascular diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60116642A (en) * 1983-11-29 1985-06-24 Nippon Kayaku Co Ltd 2-mono-substituted methyl-5,5-dimethyl-cyclo-2-hexenone derivative
EP0780122B1 (en) * 1994-09-09 2006-11-22 Shozo Koyama Depressant of functions developed by molecule
CN100384982C (en) * 2005-09-28 2008-04-30 莱阳农学院 Antrodia camphorata mycelium fermented extract and application thereof

Also Published As

Publication number Publication date
WO2008089674A1 (en) 2008-07-31
CN101225066B (en) 2010-09-22
RU2009131324A (en) 2011-02-27
IL199882A0 (en) 2010-04-15
UA97135C2 (en) 2012-01-10
CN101225066A (en) 2008-07-23
RU2422431C2 (en) 2011-06-27

Similar Documents

Publication Publication Date Title
IL199882A (en) Cyclohexenone compounds from antrodia camphorata and pharmaceutical composiitons comprising them
MY144944A (en) Novel cyclohexenone compounds from antrodia camphorata and application thereof
MX2018004347A (en) Compounds useful as immunomodulators.
MX2017016669A (en) 1, 4-substituted piperidine derivatives.
CA2990277C (en) Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same
Kang Antioxidant and anti-inflammatory effect of extracts from Flammulina velutipes (Curtis) Singer
MX2014005927A (en) Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2-signal transducer and activator of transcription 5 pathway.
GB2450189B (en) Liver protection compounds of the cyclohexenone type from Antrodia camphorata
MX2017016370A (en) Substituted 4-benzyl and 4-benzoyl piperidine derivatives.
Moran et al. Synthesis, structural characterisation and biological evaluation of fluorinated analogues of resveratrol
WO2013188417A3 (en) Treatment and prevention of cardiovascular disease and thrombosis
WO2010053340A3 (en) Skin-whitening composition
Kancheva et al. Protective effects of equimolar mixtures of monomer and dimer of dehydrozingerone with α-tocopherol and/or ascorbyl palmitate during bulk lipid autoxidation
MY171768A (en) Process and composition for inhibiting the polymerization of cyclopentadiene compounds
MX2013011132A (en) Phosphoinositide 3-kinase inhibitor with a zinc binding moiety.
SA522441650B1 (en) Topical phosphoinositide 3-kinase inhibitors
SE1750986A1 (en) Method for preparing an inhibited starch
WO2018167347A3 (en) Methods and compositions for improving plant health and/or yield
MX2021003586A (en) Personal care product customized by discrete particles and method of apply thereof.
ZA202309924B (en) Amarouciaxanthin a esters and uses thereof
WO2017064635A3 (en) Saroglitazar magnesium, compositions containing it, process for its preparation
EP4305970A3 (en) Meat analogs comprising thin flakes for food compositions
Park et al. Kojic acid derivatives, have tyrosinase inhibitory activity to suppress the production of melanin in the biosynthetic pathway
WO2014065640A3 (en) Composition for treating or preventing inflammatory diseases containing myagropsis myagroides extract or fraction thereof as active ingredient
WO2019078662A3 (en) Tyrosinase inhibition and skin-whitening activity of desmodium sequax solvent extract or fraction thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed