IL189459A0 - Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors - Google Patents

Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors

Info

Publication number
IL189459A0
IL189459A0 IL189459A IL18945908A IL189459A0 IL 189459 A0 IL189459 A0 IL 189459A0 IL 189459 A IL189459 A IL 189459A IL 18945908 A IL18945908 A IL 18945908A IL 189459 A0 IL189459 A0 IL 189459A0
Authority
IL
Israel
Prior art keywords
growth hormone
triazole derivatives
hormone secretagogue
novel triazole
ghrelin analogue
Prior art date
Application number
IL189459A
Other versions
IL189459A (en
Original Assignee
Centre Nat Rech Scient
Univ Montpellier Ii
Univ Montpellier I
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05017732A external-priority patent/EP1757290A1/en
Application filed by Centre Nat Rech Scient, Univ Montpellier Ii, Univ Montpellier I, Aeterna Zentaris Gmbh filed Critical Centre Nat Rech Scient
Publication of IL189459A0 publication Critical patent/IL189459A0/en
Publication of IL189459A publication Critical patent/IL189459A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL189459A 2005-08-15 2008-02-12 Use of triazole derivatives in the manufacture of a medicament for treating and prophylaxis of disorders, some such compounds and pharmaceutical compositions comprising some such compounds IL189459A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70794105P 2005-08-15 2005-08-15
EP05017732A EP1757290A1 (en) 2005-08-16 2005-08-16 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors
US78754306P 2006-03-31 2006-03-31
PCT/EP2006/007945 WO2007020013A2 (en) 2005-08-15 2006-08-11 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors

Publications (2)

Publication Number Publication Date
IL189459A0 true IL189459A0 (en) 2008-12-29
IL189459A IL189459A (en) 2015-08-31

Family

ID=41168847

Family Applications (1)

Application Number Title Priority Date Filing Date
IL189459A IL189459A (en) 2005-08-15 2008-02-12 Use of triazole derivatives in the manufacture of a medicament for treating and prophylaxis of disorders, some such compounds and pharmaceutical compositions comprising some such compounds

Country Status (4)

Country Link
HK (1) HK1121681A1 (en)
IL (1) IL189459A (en)
NO (1) NO342380B1 (en)
RU (1) RU2415134C9 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107438605B (en) * 2015-02-12 2021-03-19 南加利福尼亚大学 Growth hormone receptor blockers in the prevention and treatment of disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518292B1 (en) * 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
CA2389280C (en) * 1999-11-15 2009-01-27 Janssen Pharmaceutica N.V. Triazoles as farnesyl transferase inhibitors

Also Published As

Publication number Publication date
NO342380B1 (en) 2018-05-14
RU2415134C9 (en) 2011-05-27
NO20081248L (en) 2008-05-05
RU2415134C2 (en) 2011-03-27
IL189459A (en) 2015-08-31
HK1121681A1 (en) 2009-04-30
RU2008109929A (en) 2009-09-27

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Legal Events

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