IL184542A - [1,2,4]-dithiazoli(di)ne derivatives, pharmaceutical compositions comprising them and their use in the manufacture of a medicaments for the treatment of neurodegenerative diseases - Google Patents

[1,2,4]-dithiazoli(di)ne derivatives, pharmaceutical compositions comprising them and their use in the manufacture of a medicaments for the treatment of neurodegenerative diseases

Info

Publication number
IL184542A
IL184542A IL184542A IL18454207A IL184542A IL 184542 A IL184542 A IL 184542A IL 184542 A IL184542 A IL 184542A IL 18454207 A IL18454207 A IL 18454207A IL 184542 A IL184542 A IL 184542A
Authority
IL
Israel
Prior art keywords
dithiazoli
medicaments
derivatives
manufacture
treatment
Prior art date
Application number
IL184542A
Other versions
IL184542A0 (en
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/050744 external-priority patent/WO2006084854A2/en
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of IL184542A0 publication Critical patent/IL184542A0/en
Publication of IL184542A publication Critical patent/IL184542A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL184542A 2005-02-11 2007-07-11 [1,2,4]-dithiazoli(di)ne derivatives, pharmaceutical compositions comprising them and their use in the manufacture of a medicaments for the treatment of neurodegenerative diseases IL184542A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65166105P 2005-02-11 2005-02-11
EP05101004 2005-02-11
PCT/EP2006/050744 WO2006084854A2 (en) 2005-02-11 2006-02-08 [1,2,4]-dithiazoli(di)ne derivatives, inducers of gluthathione-s-transferase and nadph quinone oxido-reductase, for prophylaxis and treatment of adverse conditions associated with cytotoxicity in general and apoptosis in particular

Publications (2)

Publication Number Publication Date
IL184542A0 IL184542A0 (en) 2007-10-31
IL184542A true IL184542A (en) 2012-08-30

Family

ID=36499387

Family Applications (1)

Application Number Title Priority Date Filing Date
IL184542A IL184542A (en) 2005-02-11 2007-07-11 [1,2,4]-dithiazoli(di)ne derivatives, pharmaceutical compositions comprising them and their use in the manufacture of a medicaments for the treatment of neurodegenerative diseases

Country Status (2)

Country Link
IL (1) IL184542A (en)
NO (1) NO20074192L (en)

Also Published As

Publication number Publication date
NO20074192L (en) 2007-09-07
IL184542A0 (en) 2007-10-31

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees