IL175908A0 - Optically active, heteroaromatic ??-hydroxy esters, processes for their preparation from ??-keto esters and processes for the preparation of these ??-keto esters - Google Patents

Optically active, heteroaromatic ??-hydroxy esters, processes for their preparation from ??-keto esters and processes for the preparation of these ??-keto esters

Info

Publication number
IL175908A0
IL175908A0 IL175908A IL17590806A IL175908A0 IL 175908 A0 IL175908 A0 IL 175908A0 IL 175908 A IL175908 A IL 175908A IL 17590806 A IL17590806 A IL 17590806A IL 175908 A0 IL175908 A0 IL 175908A0
Authority
IL
Israel
Prior art keywords
processes
preparation
esters
keto
keto esters
Prior art date
Application number
IL175908A
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of IL175908A0 publication Critical patent/IL175908A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL175908A 2003-12-31 2006-05-25 Optically active, heteroaromatic ??-hydroxy esters, processes for their preparation from ??-keto esters and processes for the preparation of these ??-keto esters IL175908A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10361794A DE10361794B3 (en) 2003-12-31 2003-12-31 Optically active heteroaromatic β-hydroxy esters and processes for their preparation and their use as intermediates in the epothilone total synthesis
PCT/EP2004/014753 WO2005064006A1 (en) 2003-12-31 2004-12-21 OPTICALLY ACTIVE, HETEROAROMATIC β-HYDROXY ESTERS, PROCESSES FOR THEIR PREPARATION FROM β-KETO ESTERS AND PROCESSES FOR THE PREPARATION OF THESE β-KETO ESTERS

Publications (1)

Publication Number Publication Date
IL175908A0 true IL175908A0 (en) 2006-10-05

Family

ID=34716267

Family Applications (1)

Application Number Title Priority Date Filing Date
IL175908A IL175908A0 (en) 2003-12-31 2006-05-25 Optically active, heteroaromatic ??-hydroxy esters, processes for their preparation from ??-keto esters and processes for the preparation of these ??-keto esters

Country Status (17)

Country Link
EP (1) EP2113031A1 (en)
JP (1) JP2007516999A (en)
KR (1) KR20070029641A (en)
CN (1) CN100510098C (en)
AU (1) AU2004309076A1 (en)
BR (1) BRPI0418254A (en)
CA (1) CA2546981A1 (en)
CR (1) CR8492A (en)
DE (1) DE10361794B3 (en)
EC (1) ECSP066740A (en)
HK (1) HK1097000A1 (en)
IL (1) IL175908A0 (en)
MX (1) MXPA06007564A (en)
NO (1) NO20063477L (en)
RU (1) RU2006127553A (en)
WO (1) WO2005064006A1 (en)
ZA (1) ZA200606293B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104328152A (en) * 2014-10-13 2015-02-04 青岛科技大学 Method for catalytically producing cyclohexylidene enol by utilizing candida utilis
CN108118004B (en) * 2017-12-15 2021-06-25 北京工商大学 Application of pichia stipitis in preventing and treating postharvest diseases of fruits
CN116159601A (en) * 2019-03-15 2023-05-26 博瑞生物医药(苏州)股份有限公司 Eribulin intermediate and preparation method thereof
CN110283733B (en) * 2019-06-20 2020-10-27 浙江工业大学 Tupistra yeast ZJPH1807 and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997012884A1 (en) * 1995-10-04 1997-04-10 Fmc Corporation Herbicidal 6-heterocyclic indazole derivatives
US5942644A (en) * 1997-05-27 1999-08-24 Biocatalytics, Inc. Precursors for the production of chiral vicinal aminoalcohols
US6211412B1 (en) * 1999-03-29 2001-04-03 The University Of Kansas Synthesis of epothilones
PE20010116A1 (en) * 1999-04-30 2001-02-15 Schering Ag 6-ALKENYL-, 6-ALKINYL- AND 6-EPOXY-EPOTILONE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION
JP2001213874A (en) * 1999-07-22 2001-08-07 Mercian Corp Production of isocoumarin derivative and intermediate therefor
DE10041470A1 (en) * 2000-08-18 2002-02-28 Schering Ag New 6-substituted 12,13-(cyclopropyl or azacyclopropyl)-epothilone derivatives, useful as cell division regulators for treating e.g. malignant tumors, psoriasis or arthritis
WO2003029195A1 (en) * 2001-09-28 2003-04-10 Sumika Fine Chemicals Co., Ltd. Intermediates for epothilone derivative and process for producing these
JP4432315B2 (en) * 2002-03-19 2010-03-17 三菱化学株式会社 Process for producing optically active 3-hydroxy-3- (2'-thienyl) propionic acid ester derivative

Also Published As

Publication number Publication date
BRPI0418254A (en) 2007-04-17
NO20063477L (en) 2006-08-23
HK1097000A1 (en) 2007-06-15
CN1902322A (en) 2007-01-24
ECSP066740A (en) 2006-10-31
MXPA06007564A (en) 2006-12-14
EP2113031A1 (en) 2009-11-04
RU2006127553A (en) 2008-02-10
ZA200606293B (en) 2009-08-26
CN100510098C (en) 2009-07-08
AU2004309076A1 (en) 2005-07-14
CA2546981A1 (en) 2005-07-14
KR20070029641A (en) 2007-03-14
CR8492A (en) 2007-03-08
JP2007516999A (en) 2007-06-28
WO2005064006A1 (en) 2005-07-14
DE10361794B3 (en) 2005-10-06

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